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Lysis and hypotonic sonication buffers for ChIP assays

Offering complete disruption of cytoplasmic and nuclear membranes, Porvair Sciences Chromatrap® buffer chemistries are optimised for sonication and enzymatic shearing.

From Porvair Sciences Limited 29 Nov 2022

Antioxidant and anti-inflammatory properties of Stingless bee-derived propolis against acne

Researchers explore the anti-acne, antioxidant, and anti-inflammatory properties of Stingless bee (Tetragonula biroi)-derived propolis.

29 Nov 2022

New biosensing platform detects SARS-CoV-2 antibodies in five minutes

Rapid, cheap and accurate tests continue to be essential for epidemiological surveillance and for health services to monitor and contain the spread of SARS-CoV-2. Brazilian scientists have contributed to endeavors in this field by developing an electrochemical immunosensor that detects antibodies against the virus.

29 Nov 2022

SARS-CoV-2 RNA found to be present in various environmental surface samples

Researchers conducted environmental surveillance of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ribonucleic acid (RNA).

29 Nov 2022

Cryo-electron tomography helps visualize platelet deformation due to SARS-CoV-2 spike protein

Researchers used cellular cryo-electron tomography (cryo-ET) to demonstrate the role of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) protein in coronavirus disease 2019 (COVID-19)-triggered severe coagulopathies.

28 Nov 2022

Using human iPSC-derived cells to revolutionize the field of neurodegenerative disease

In this interview, we speak to Axol Bioscience about their human iPSC-derived cells and how they have the potential to revolutionize the field of neurodegenerative disease.

From Axol Bioscience Ltd 28 Nov 2022

New technologies and recent advances in the study of T cells and T-cell epitope discovery in food allergy research

In a recent study, scientists reviewed the latest technological advancements and T cell epitope discovery associated with food allergy.

28 Nov 2022

Memory B and T cells responses differ when induced by SARS-CoV-2 infections or booster vaccinations

In a recent study published in The Journal of Immunology, a team of researchers from Japan examined the memory B and T cell responses to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein after the booster dose of the coronavirus disease 2019 (COVID-19) messenger ribonucleic acid (mRNA) vaccine BNT162b2.

27 Nov 2022

Nanoparticles displaying SARS-CoV-1 and SARS-CoV-2 spikes induce broad antibody responses in animal model

A recent study published in the journal iScience reported that nanoparticles (NPs) co-displaying spike proteins from different sarbecoviruses improve the breadth of neutralizing responses.

27 Nov 2022

The relationship between neutralization levels and observed efficacies against asymptomatic and symptomatic infection of ten COVID-19 vaccines

Researchers determined whether neutralizing antibody levels were predictive of the efficacy of fractional vaccine doses against SARS-CoV-2 infection.

24 Nov 2022

The safety and immunogenicity of a fourth dose of NVX-CoV2373

Researchers assessed the immunogenicity and safety of a fourth homologous boost dose of a recombinant SARS-CoV-2 spike protein vaccine called NVX-CoV2373.

23 Nov 2022

Novel mRNA vaccines encoding Monkeypox virus proteins show promise in preclinical studies

In a recent study posted to the bioRxiv* preprint server, researchers in China demonstrated the efficacy of three messenger ribonucleic acid (mRNA) technology-based Monkeypox virus (MPXV) vaccines in combating a lethal Vaccinia virus (VACV) challenge in mice models.

22 Nov 2022

Plant-based monoclonal antibody increases potency of antibody cocktail against SARS-CoV-2 Omicron variant

A novel mAb against the SARS-CoV-2 RBD through a hybridoma technique, followed by chimerization and expression in plants.

22 Nov 2022

Potent hypervalent nanoparticles against HIV, Lassa and SARS-CoV-2 variants

In a recent study published in the journal Advanced Science, researchers developed molecularly imprinted nanoparticles (nanoMIPs) with broad-spectrum activity against lethal viruses.

21 Nov 2022

Kiwira virus: a new bat-borne hantavirus detected in Africa

Researchers discover a novel hantavirus called the Kiwira virus.

21 Nov 2022

New method for isolating Omicron subvariant and evaluating resistance to therapeutic and vaccine-elicited antibodies

Researchers demonstrated a viral amplification procedure to isolate the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron subvariants.

21 Nov 2022

Evaluating cell-free DNA-based blood tests for early detection of multiple cancers

Researchers assessed several approaches for a circulating cell-free deoxyribonucleic acid (cfDNA)-based multi-cancer early detection (MCED) test. Defining the clinical limit of detection (LOD) based on circulating tumor allele fraction (cTAF) enables the comparison of different approaches.

21 Nov 2022

Assay News and Research

Lysis and hypotonic sonication buffers for ChIP assays

Antioxidant and anti-inflammatory properties of Stingless bee-derived propolis against acne

New biosensing platform detects SARS-CoV-2 antibodies in five minutes

SARS-CoV-2 RNA found to be present in various environmental surface samples

Cryo-electron tomography helps visualize platelet deformation due to SARS-CoV-2 spike protein

Using human iPSC-derived cells to revolutionize the field of neurodegenerative disease

New technologies and recent advances in the study of T cells and T-cell epitope discovery in food allergy research

Memory B and T cells responses differ when induced by SARS-CoV-2 infections or booster vaccinations

Nanoparticles displaying SARS-CoV-1 and SARS-CoV-2 spikes induce broad antibody responses in animal model

The relationship between neutralization levels and observed efficacies against asymptomatic and symptomatic infection of ten COVID-19 vaccines

The safety and immunogenicity of a fourth dose of NVX-CoV2373

Novel mRNA vaccines encoding Monkeypox virus proteins show promise in preclinical studies

Plant-based monoclonal antibody increases potency of antibody cocktail against SARS-CoV-2 Omicron variant

Potent hypervalent nanoparticles against HIV, Lassa and SARS-CoV-2 variants

Kiwira virus: a new bat-borne hantavirus detected in Africa

New method for isolating Omicron subvariant and evaluating resistance to therapeutic and vaccine-elicited antibodies

Evaluating cell-free DNA-based blood tests for early detection of multiple cancers

WHO‒recommended alcohol-based hand rub formulations show efficacy against Monkeypox virus

Chitin-immobilized nanobodies for SARS-CoV-2 detection

SARS-CoV-2 infection and mRNA vaccination prime transcriptionally distinct CD4+ T cell memory landscapes

eBook: Using iPSCs models for human disease research and drug discovery eBook

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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