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FIND, NUS collaborate to identify novel biomarkers for TB diagnosis

A research team from the National University of Singapore (NUS) Singapore Lipidomics Incubator (SLING) is collaborating with the Foundation for Innovative New Diagnostics (FIND) to identify novel target molecules to be employed as biomarkers for the detection of active tuberculosis.

15 Dec 2011

Potential budget cuts threaten U.S. military HIV research program

This post in the Center for Global Health Policy's "Science Speaks" blog examines how potential budget cuts are threatening the Walter Reed Army Institute of Research (WRAIR) Military HIV Research Program (MHRP), "a $175 million program supported by the Department of Defense and other entities that is vulnerable to cuts in the fiscal year 2012 funding battle currently taking place on the Hill."

15 Dec 2011

Viewpoints: Berwick's advice; Romney's wager; Fighting AIDS

Dr. Donald Berwick, who was blocked by Republicans from serving a full term as the administrator of the agency that runs Medicare and Medicaid, has been speaking out. He makes a compelling case about the harm caused by partisan demagoguery and about the need for health care professionals to take the lead in implementing reforms.

15 Dec 2011

Chevron's role in fight against HIV/AIDS in Africa

In this Africa.com opinion piece, Ana Ruth Luis, medical director of the Southern Africa Strategic Business Unit at Chevron Africa and Latin America Ex in Angola, discusses what she calls "the important role Chevron has in driving down the incidence of HIV/AIDS in Africa."

15 Dec 2011

Discrimination against LGBT population undermining HIV prevention efforts in Guatemala, IPS reports

Inter Press Service examines discrimination against lesbian, gay, bisexual and transgender (LGBT) people in Guatemala, where advocates and non-governmental organizations (NGOs) say such discrimination is undermining HIV prevention and treatment. Carolos Valdez of the NGO Proyecto Unidos "said the country has taken 'few steps' for preventing the spread of HIV among vulnerable groups," including "opening five clinics catering to members of sexual minorities," IPS writes.

15 Dec 2011

First mobile safety lab for South African patients with AIDS and TB

The first mobile safety laboratory to operate under Biosafety Level 3 has been in use in South Africa since May 2011. As development of the Fraunhofer Institute for Biomedical Engineering in St. Ingbert, this special truck is used for testing and advising patients with AIDS and tuberculosis. The mobile laboratory can save patients' lives in remote areas because it cuts the waiting time between diagnosis and the start of treatment to just one day.

15 Dec 2011

Researchers discover novel viral oncogenesis mechanism

Human tumor viruses contribute to 15-20% of human cancers worldwide. Kaposi's sarcoma herpesvirus (KSHV) is an etiological agent for Kaposi's sarcoma (KS) and two other rare lymphoproliferative malignancies. KS is the most common cancer in HIV-infected untreated individuals and remains a primary cause of cancer deaths in many subequatorial African countries as a result of the AIDS pandemic.

15 Dec 2011

Alcohol intake linked to unsafe sex

It is known that unprotected sexual intercourse is the most common cause of HIV infection and finding ways to prevent unsafe sex is a major goal of public health efforts to prevent HIV/AIDS. It has not been clear whether unsafe sex associated with alcohol use actually led to HIV infection, or whether certain personality traits, such as sensation-seeking or risky behavior, led to both alcohol use and unsafe sex.

14 Dec 2011

Salix submits Crofelemer NDA to FDA for treatment of HIV-associated diarrhea

Salix Pharmaceuticals, Ltd. today announced that the Company has submitted to the U.S. Food and Drug Administration (FDA) a New Drug Application (NDA) for Crofelemer for the proposed treatment of HIV-associated diarrhea.

14 Dec 2011

Fresh cells can pep talk immune cells exhausted by HIV or hepatitis C

Chronic infections by viruses such as HIV or hepatitis C eventually take hold because they wear the immune system out, a phenomenon immunologists describe as exhaustion.

14 Dec 2011

Use of rapid male circumcision tool will help Africa reach HIV prevention goals

In order for Rwanda to reach its HIV prevention goals, the country "need[s] to reach two million men in two years to benefit from the protective effect of [voluntary medical male circumcision] in order to achieve this as part of a comprehensive, combination HIV prevention strategy," Agnes Binagwahois, Rwanda's minister of health, writes in a Washington Post opinion piece.

14 Dec 2011

Maraviroc reduces incidence of GvHD in blood cancer patients after ASCT

An HIV drug that redirects immune cell traffic appears to significantly reduce the dangerous complication graft-versus-host disease (GvHD) in blood cancer patients following allogeneic stem cell transplantation (ASCT), according to new research from the Perelman School of Medicine at the University of Pennsylvania that will be presented today at the 53rd American Society of Hematology Annual Meeting.

14 Dec 2011

Canadian researchers develop portable device to monitor HIV in rural areas

A team of Canadian researchers has "created a portable device that uses a computer chip with software capable of analyzing blood tests outside the lab ... that could make it easier, faster and cheaper to track the progression of HIV in patients living in the developing world," Postmedia News/Vancouver Sun reports.

14 Dec 2011

U.S. investments in HIV treatment internationally, domestically 'should pay off'

"We welcome the Obama administration's announcement of a farsighted effort to treat millions more people living with HIV abroad, especially in sub-Saharan Africa," a New York Times editorial writes.

14 Dec 2011

People in Swaziland protesting shortages of ARVs amid government financial crisis

In Swaziland, where a "deepening financial crisis is taking a toll on service delivery, and the country is experiencing an unprecedented number of protests over issues such as school closures and a lack of HIV treatment," "a new wave of HIV activism is rising ... as people living with HIV take to the streets in protest, many for the first time in their lives, over continued shortages of antiretroviral (ARV) treatment," PlusNews reports.

14 Dec 2011

Central African Republic in state of 'chronic medical emergency,' MSF report says

"The Central African Republic (CAR) is in the grips of a chronic medical emergency, according to a report released today by the international medical humanitarian organization Doctors Without Borders/Medecins Sans Frontieres (MSF)," an MSF press release states.

14 Dec 2011

Aethlon Hemopurifier can capture Nef protein exosomes linked with HIV

Aethlon Medical, Inc., the pioneer in developing therapeutic filtration devices to address infectious disease and cancer, announced today that researchers have discovered that the Aethlon Hemopurifier is able to capture particles known as Nef protein exosomes, which contribute to the progression of human immunodeficiency virus (HIV) infection to acquired immunodeficiency syndrome.

14 Dec 2011

Unexplained kidney disease affecting rural workers across Central America, PRI's 'The World' reports

PRI's "The World" reports on an epidemic of an unexplained kidney disease that is affecting rural workers across Central America, writing, "[I]t's the second biggest cause of death among men in El Salvador, and in Nicaragua it's a bigger killer of men than HIV and diabetes combined," and "the latest theory is that the victims are literally working themselves to death."

14 Dec 2011

U.S. acting to link GBV, HIV efforts

In this post in the U.S. Department of State's "DipNote" blog, U.S. Global AIDS Coordinator Ambassador Eric Goosby and Melanne Verveer, ambassador-at-large for global women's issues, report on the relationship between gender-based violence (GBV) and HIV.

13 Dec 2011

Drug users with HIV infection have 74% higher risk of overdose

A study from Rhode Island Hospital is the first to systematically review and analyze the literature on the association between HIV infection and overdose risk.

13 Dec 2011