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UNIGE researchers discover why premature cell division promotes tumor formation

The accumulation of mutations in the human genome is at the origin of cancers, as well as the development of resistance to treatments. The Cyclin E and Myc genes are active in the control of cell division.

28 Feb 2018

RNA-based method cures lung tumors in mice

By turning down the activity of a specific RNA molecule researchers at Sahlgrenska Academy, Sweden, have cured lung tumors in mice by 40-50 percent.

28 Feb 2018

Scientists map breast cancer's spread routes

Breast cancer spreads to other organs in the body according to certain specific patterns. This has been shown by a team of researchers from Karolinska Institutet and KTH in Sweden and the University of Helsinki in Finland who have mapped breast cancer's spread routes in patients by studying the cancer cells' DNA. The study is published in The Journal of Clinical Investigation.

27 Feb 2018

MD Anderson and RaySearch partner to enhance cancer radiation therapy

The University of Texas MD Anderson Cancer Center and RaySearch Laboratories today announced a strategic alliance with the aim of enhancing cancer radiation therapy through several initiatives, including more precisely targeting of tumors and improving upon, and making more available, an existing radiation therapy called adaptive radiation therapy, currently only used at highly specialized care centers.

From RaySearch Laboratories AB 27 Feb 2018

Dual thermal ablation can kill pancreatic cancer cells, research shows

A heating and freezing process known as dual thermal ablation can kill pancreatic cancer cells, according to new research from Binghamton University, State University at New York.

27 Feb 2018

Research reveals how mutant p53 enhances tumor metastasis

Scientists at The Wistar Institute have found a novel mechanism through which mutant p53 enhances metastasis by controlling tumor metabolism. The research, published online in Genes & Development, also revealed how this process is influenced by a naturally occurring p53 gene variant.

26 Feb 2018

Combined analysis makes risk prediction for colorectal cancer more precise

If first-degree relatives are affected by colorectal cancer, this indicates a person's own elevated risk of developing bowel cancer. The same holds true for people who have large numbers of genetic risk markers in their genome.

26 Feb 2018

UC Riverside researchers discover way to halt cancer metastasis

A research team at the University of California, Riverside has discovered a way for chemotherapy drug paclitaxel to target migrating, or circulating, cancer cells, which are responsible for the development of tumor metastases.

23 Feb 2018

Stiffness of cancer cell plasma membrane affects uptake of nanomedicines

Nanomedicines need to get taken up by diseased cells in order to release their cargo. Cancer cells have altered membrane properties, which hamper their ability to take up nanomedicines.

23 Feb 2018

Efficacy of cancer immunotherapy increased by deactivating tumor defence mechanism

Novel bifunctional immunotherapeutic agents have been developed that, as well as deactivating key immune checkpoints,deactivate the tumor's protective response.

23 Feb 2018

UT Dallas researchers use new technique to isolate cancer stem cells

Researchers at The University of Texas at Dallas have devised a new technique to isolate aggressive cells thought to form the root of many hard-to-treat metastasized cancers -- a significant step toward developing new drugs that might target these cells.

22 Feb 2018

Epigenetic changes due to normal aging process linked to cancer risk

Some scientists have hypothesized that tumor-promoting changes in cells during cancer development--particularly an epigenetic change involving DNA methylation--arise from rogue cells escaping a natural cell deterioration process called senescence.

22 Feb 2018

Aggressive cancer stem cells can now be isolated successfully in a scientific breakthrough

University of Texas at Dallas researchers have managed to formulate a new technique by which they can isolate aggressive cells which can be the main cause behind metastasized cancers or cancers that have spread to other major organs from their primary site of occurrence.

22 Feb 2018

Zika virus could be alternative for treatment of aggressive brain cancer

Zika virus, feared for causing microcephaly in babies whose mothers were infected during pregnancy by attacking the cells that will give rise to the fetus's cerebral cortex, could be an alternative for treatment of glioblastoma, the most common and aggressive kind of malignant brain tumor in adults.

21 Feb 2018

Local environment plays crucial role in aggressiveness of breast cancer

Breast cancer is the most commonly diagnosed cancer in women -- one in eight (12.4 percent) in the U.S. will be diagnosed with it. Invasive breast cancer is dangerous for two reasons: It can aggressively spread to other organs in the body, and it is likely to recur.

21 Feb 2018

Researchers discover five new genetic changes that may increase pancreatic cancer risk

In what is believed to be the largest pancreatic cancer genome-wide association study to date, researchers at the Johns Hopkins Kimmel Cancer Center and the National Cancer Institute, and collaborators from over 80 other institutions worldwide discovered changes to five new regions in the human genome that may increase the risk of pancreatic cancer.

21 Feb 2018

Scientists show that cutting-edge technique can efficiently sort nano-sized particles

A new cellular messenger discovered by Weill Cornell Medicine scientists may help reveal how cancer cells co-opt the body's intercellular delivery service to spread to new locations in the body.

From Waters | Wyatt Technology 21 Feb 2018

Advanced method holds promise for substantial improvements in breast cancer diagnosis

Enhancing the diagnosis of breast cancer is the stated goal of a research team at the German Cancer Research Center in Heidelberg. The scientists have combined an advanced method of diffusion-weighted MR imaging with intelligent image analysis methods to detect malignant changes in tissues.

21 Feb 2018

Cancer initiation found to be similar across organs

Recent research at Washington University School of Medicine in St. Louis demonstrated that mature cells in the stomach sometimes revert back to behaving like rapidly dividing stem cells.

21 Feb 2018

Some genes can drive both metastasis and initial stages of tumor growth

In spite of the difference between the cell functions responsible for giving rise to a tumor and for the metastasis of this same tumor, studies at IRB Barcelona using the fly Drosophila melanogaster reveal that some genes can drive both phenomena.

21 Feb 2018