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Partial loss of MYLPF gene can cause distal arthrogryposis, shows study

Jared Talbot is part of a 32-member international research team that identified a gene that, when altered, can cause bent fingers and toes, clubfoot, scoliosis, and short stature.

30 Jul 2020

Relatives of SARS-CoV-2 may pose a health threat for years to come

Coronaviruses are zoonotic viruses that jump from animals to humans and cause infection. There are many types of common human coronaviruses, which usually cause mild to moderate upper-respiratory tract illnesses, like the common cold. Most people get infected with one or more of coronavirus types 229E, NL63, OC43, and HKU1 at some point in their lives.

29 Jul 2020

New approach shows promise for treating shoulder pain in wheelchair users with spinal cord injury

Researchers in regenerative rehabilitation conducted a pilot study of a new approach to the treatment of treatment-resistant shoulder pain in wheelchair users with spinal cord injury (SCI) and rotator cuff disease.

29 Jul 2020

UC San Diego researchers part of special package of human genome studies

Researchers at University of California San Diego School of Medicine are among the contributors to a package of 10 studies, published July 29, 2020 in the journal Nature, describing the latest results from the ongoing Encyclopedia of DNA Elements (ENCODE) project, a worldwide effort led by the National Institutes of Health to understand how the human genome functions.

29 Jul 2020

Iota-carrageenan from red seaweed inhibits SARS-CoV-2 in laboratory conditions

In a recent bioRxiv paper, a research group from the Marinomed Biotech biopharmaceutical company in Austria showed that a sulfated polysaccharide iota-carrageenan has the propensity to inhibit cell entry of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by using an in vitro neutralization assay.

29 Jul 2020

Experts caution against routine use of current GEP tests for melanoma patients

A consensus statement published today in JAMA Dermatology by an international group of melanoma researchers evaluates the use of prognostic genetic expression profile (GEP) testing to guide clinical management of patients with melanoma.

29 Jul 2020

New maps of chemical marks on DNA could help illuminate the causes of developmental disorders

In research that aims to illuminate the causes of human developmental disorders, Salk scientists have generated 168 new maps of chemical marks on strands of DNA--called methylation--in developing mice.

29 Jul 2020

Study reveals mechanisms of mechanical stretch induced skin expansion

The capacity of the skin to expand by mechanical stretching has been used for decades in plastic and reconstructive surgery to generate an excess of skin that can be used to repair birth defects, damaged tissues, and breast reconstruction after mastectomy.

29 Jul 2020

Stand Up To Cancer announces $1.1 million in funding to foster collaborative research

Stand Up To Cancer announced today five new awards that will cut across institutional and national lines to foster collaborative research and explore new paths to improve cancer treatment.

29 Jul 2020

WHO and NDWG launch framework for evaluation of new tests for TB infection

WHO and the Stop TB Partnership's New Diagnostics Working Group launched today a framework for the evaluation of new tests for tuberculosis infection.

29 Jul 2020

New study shows the mechanism of brain to recognize specific smells

An Italian-American research conducted by researchers at the IIT-Istituto Italiano di Tecnologia (Italian Institute of Technology) in Rovereto (Italy) and Harvard University in Boston (Usa) explains for the first time the mechanisms used by our brain to recognize specific smells.

29 Jul 2020

New method can detect small amounts of protein fragment linked to Alzheimer's disease

Researchers at Washington University School of Medicine in St. Louis have developed a technique to detect minute amounts of a protein fragment linked to Alzheimer's disease in the blood.

29 Jul 2020

Computed tomography can serve as effective tool for diagnosing COVID-19

The use of computed tomography in outpatient computed tomography centers (OCTC) is entirely consistent with the clinical data and global best practices. This is also an effective tool for diagnosing the coronavirus infection COVID-19

29 Jul 2020

Exciting cost-effective SARS-CoV-2 vaccine candidate using Newcastle disease

Experts warn that the world may see repeated waves of the COVID-19 pandemic. However, scientists around the world are working hard to create a protective vaccine or antiviral, which could help to reduce the number of deaths and cases the next time around.

29 Jul 2020

Basigin/CD147 discarded as an accessory SARS-CoV-2 binding receptor

By using specialized assays customized to detect specific receptor interactions, researchers from the Wellcome Sanger Institute in Cambridge UK find no evidence for direct binding of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein to a transmembrane glycoprotein known as basigin.

28 Jul 2020

Emergent SARS-CoV-2 D614G spike mutation more infective due to "open" morphology

Researchers from the Los Alamos National Laboratory and Duke Human Vaccine Institute & Department of Surgery demonstrated that globally prevalent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) with the amino acid substitution D614G in the spike protein is much more infective due to profitable binding encounters with the host receptors.

28 Jul 2020

'Synthetic lethality' could be exploited for cancer therapy

A Ludwig Cancer Research study has identified a new instance in which the simultaneous mutation of two nonessential genes--neither of which is on its own vital to cell survival--can cause cancer cell death.

28 Jul 2020

Computational analyses suggest new pathway for inflammatory response to SARS-CoV-2

Analyses of lung fluid cells from COVID-19 patients conducted on the nation's fastest supercomputer point to gene expression patterns that may explain the runaway symptoms produced by the body's response to SARS-CoV-2.

28 Jul 2020

New multi-analyte blood test may open up new potentials in personalized medicine

Similar to blood sugar, various biomarkers could in future be identified using just a few drops of blood. Researchers at Ruhr-Universität Bochum are developing a multi-analyte test strip for this purpose that will open up new potentials in personalised medicine by facilitating the continuous measurement of various parameters.

28 Jul 2020

OU physician receives $1.6 million NIH grant for knee osteoarthritis research

By the time they turn 65, at least half of people suffer from osteoarthritis, a condition that impairs quality of life and cannot be slowed by medication.

28 Jul 2020