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Dresden researchers develop molecular smoke alert for key human cancer gene

If it burns in a house smoke detectors alert us hence protecting life. A molecular smoke alert has now been developed by Dresden researchers for the TP53 gene, the most important human cancer gene. The alert goes on if the TP53 gene is mutated in cells.

14 Nov 2017

Using AFM to study cancer cells

An interview with Prof. Hermann Schillers, Universität Münster conducted by April Cashin-Garbutt, MA (Cantab).

From Bruker Nano Surfaces and Metrology 14 Nov 2017

Novel AR glasses help doctors to locate lymph nodes during surgery

Malignant tumors often form metastases that spread to other parts of the body via the lymphatic system. High surgical skills are required to identify the precise location of the affected lymph nodes, enabling them to be completely removed.

14 Nov 2017

Absence of VEGF-A in cancer-killing T cells accelerates tumor development

Contrary to what was previously believed, the immune system's cancer-killing T cells are more effective in a tumour's anoxic environment when they have access to growth factor VEGF-A.

13 Nov 2017

Epigenetic editing in healthy breast cells can set off chain reaction for tumor initiation

Changing the epigenetic code of a single gene is enough to cause a healthy breast cell to begin a chain reaction and become abnormal, according to research by Queen Mary University of London.

13 Nov 2017

Study identifies novel mechanism by which tumors can resist cancer immunotherapy

A Ludwig Cancer Research study led by Benoit Van den Eynde, Director of Ludwig Brussels, has identified a novel mechanism by which tumors of the aggressive skin cancer melanoma can resist cancer immunotherapy.

10 Nov 2017

Russian scientists uncover previously unknown effect of leukemia drug

Researchers from RUDN University and Institute of Biomedical Chemistry of the Russian Academy of Sciences have identified an alternative mechanism for the effective antitumor drug -- an enzyme called L-asparaginase.

10 Nov 2017

Common genetic fusion event could help identify patients with low-risk prostate cancer

Establishing the way in which a genetic alteration called a TMPRSS2-ERG gene fusion forms in a prostate cancer, rather than the presence of the gene fusion itself, could help identify patients with prostate cancer with a low risk of spreading, which might determine the best course of treatment for the patient.

10 Nov 2017

Elevated levels of chronic stress hormones may promote EGFR inhibitor resistance in NSCLC patients

Elevated levels of chronic stress hormones, such as those produced by psychological distress, may promote resistance to drugs commonly used to treat lung cancer patients with EGFR mutations, according to new research from The University of Texas MD Anderson Cancer Center.

9 Nov 2017

Novel mathematical model can predict how cancer patient will benefit from immunotherapies

Researchers at the Icahn School of Medicine at Mount Sinai have created the first mathematical model that can predict how a cancer patient will benefit from certain immunotherapies, according to a study published in Nature.

9 Nov 2017

3D cultured spheroids could drive precision treatment for ovarian cancer

Honeycomb-like arrays of tiny, lab-grown cancers could one day help doctors zero in on individualized treatments for ovarian cancer, an unpredictable disease that kills more than 14,000 women each year in the United States alone.

9 Nov 2017

Researchers find way to improve immunotherapy drugs’ impact while limiting side effects

By connecting highly effective cancer immunotherapy drugs such as anti-CTLA4 (ipilimumab) and anti-PD-L1 (atezolizumab) to peptides that bind to tissues in and around tumors, a research team based at the University of Chicago found a way to improve the drugs' impact while limiting treatment-related side effects.

9 Nov 2017

Scientists uncover mechanism that prevents tumor growth in melanoma

Natural Killer (NK) cells, lymphocytes of the innate immune system with strong cytotoxic activity, play a major role in the immune response against tumors.

8 Nov 2017

Researchers use gold nanoshells to effectively release cancer drugs inside tumors

Researchers investigating ways to deliver high doses of cancer-killing drugs inside tumors have shown they can use a laser and light-activated gold nanoparticles to remotely trigger the release of approved cancer drugs inside cancer cells in laboratory cultures.

8 Nov 2017

Chronic liver inflammation promotes cancer by suppressing immunosurveillance, study finds

Chronic inflammation is known to drive many cancers, especially liver cancer. Researchers have long thought that's because inflammation directly affects cancer cells, stimulating their division and protecting them from cell death.

8 Nov 2017

Novel approach could help predict how well patients respond to cancer treatment

A novel approach developed by researchers from the University of Leicester and the MRC Toxicology Unit could help to predict how well patients respond to drugs designed to fight various forms of cancer.

8 Nov 2017

UVA examines scalpel-free surgery's potential to help the body destroy breast cancer cells

In its latest pioneering effort to harness the power of focused ultrasound to battle disease, the University of Virginia Health System is examining the scalpel-free surgery's potential to enable the body to identify and destroy metastatic breast cancer cells.

8 Nov 2017

New program targets cancers affecting the liver and bile ducts

Cancers affecting the liver and bile ducts will be the target of a new program at Perlmutter Cancer Center at NYU Langone Health to provide multidisciplinary clinical care and rapidly bring important new research to the clinic.

7 Nov 2017

Researchers find new way to restrict ability of cancer to use glucose for energy

Cancer cells consume exorbitant amounts of glucose, a key source of energy, and shutting down this glucose consumption has long been considered a logical therapeutic strategy.

7 Nov 2017

Study reveals link between circulating tumor cells and relapse in late-stage melanoma patients

A study revealing a connection between circulating tumor cells (CTCs) and relapse in stage IV melanoma patients points to liquid biopsy as a potential predictor of patients at high risk for disease progression. CTCs, tumor cells shed into the bloodstream or lymphatic system, can lead to additional tumor growth and/or metastasis to distant sites.

7 Nov 2017

Tumor News and Research

Dresden researchers develop molecular smoke alert for key human cancer gene

Using AFM to study cancer cells

Novel AR glasses help doctors to locate lymph nodes during surgery

Absence of VEGF-A in cancer-killing T cells accelerates tumor development

Epigenetic editing in healthy breast cells can set off chain reaction for tumor initiation

Study identifies novel mechanism by which tumors can resist cancer immunotherapy

Russian scientists uncover previously unknown effect of leukemia drug

Common genetic fusion event could help identify patients with low-risk prostate cancer

Elevated levels of chronic stress hormones may promote EGFR inhibitor resistance in NSCLC patients

Novel mathematical model can predict how cancer patient will benefit from immunotherapies

3D cultured spheroids could drive precision treatment for ovarian cancer

Researchers find way to improve immunotherapy drugs’ impact while limiting side effects

Scientists uncover mechanism that prevents tumor growth in melanoma

Researchers use gold nanoshells to effectively release cancer drugs inside tumors

Chronic liver inflammation promotes cancer by suppressing immunosurveillance, study finds

Novel approach could help predict how well patients respond to cancer treatment

UVA examines scalpel-free surgery's potential to help the body destroy breast cancer cells

New program targets cancers affecting the liver and bile ducts

Researchers find new way to restrict ability of cancer to use glucose for energy

Study reveals link between circulating tumor cells and relapse in late-stage melanoma patients

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Exploring the G:Box and for high-quality imaging

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