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Proteomics approach helps identify protein signatures that can improve detection of prediabetes

Scientists have used a proteomics approach to identify a three-protein signature in the blood that can improve detection of isolated impaired glucose tolerance, a form of prediabetes.

10 Nov 2022

Researchers demonstrate that neutralizing antibody titers wane over time in ChAdOx1, BNT162b2 and mRNA-1273 vaccinees

Researchers investigated the neutralization antibody titers and the efficacy of the humoral and cellular immunities in individuals vaccinated with three COVID-19 vaccines.

10 Nov 2022

MicroRNAs can upregulate proteins in addition to downregulating protein production

microRNAs can play a role in cancer development and are thought to exclusively suppress protein expression in dividing cells, such as tumor cells.

10 Nov 2022

Empty lipid nanoparticles trigger maturation and activation of antigen-presenting cells

In a recent study posted to the Research Square* preprint server and under review at the Nature Portfolio journal, researchers reported activation and maturation of antigen-presenting cells (APCs) by lipid nanoparticles (LNPs).

9 Nov 2022

Immunological responses against monkeypox virus concerning the 2022 outbreak

A new study aimed to analyze the kinetics of the pox-specific T-cell induction, the inflammatory profile, and the inflammatory profile in human cases of the current monkeypox outbreak.

9 Nov 2022

Researchers propose a deep antibody-antigen interaction algorithm to accelerate the identification of potential therapeutic antibodies

Researchers used a deep antibody-antigen interaction (DeepAAI) algorithm to understand the antibody representations of unseen antibodies to accelerate the discovery of novel antibodies with potential therapeutic applications.

9 Nov 2022

Researchers identify 55 broadly reactive monoclonal antibodies to betacoronaviruses

In a recent study published in the journal Cell Host & Microbe, researchers pursued novel approaches that could help find monoclonal antibodies (mAbs) broadly targeting coronaviruses (CoVs), especially genera beta CoVs.

8 Nov 2022

Study identifies novel inhibitors against SARS-CoV-2 main protease

In a recent study posted to the bioRxiv* server, researchers at the University of Arizona screened ~11 million severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) main protease (MPro)-inhibiting small compounds in the ZINC15 database using a structure-based in-silico screening method.

8 Nov 2022

SARS-CoV-2 activates NLRP3 inflammasome

Researchers assessed the role of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the NLR family pyrin domain containing 3 (NLRP3) inflammasome activation.

7 Nov 2022

Llusern debuts Lodestar UTI molecular diagnostic platform at Medica 2022

UK diagnostics manufacturer, Llusern Scientific, will preview its Lodestar DX molecular platform at Medica 2022 in Dusseldorf (14-17 November).

From Llusern Scientific Ltd. 7 Nov 2022

Study suggests anti-PF4 antibodies may play a role in the severe multiorgan disease manifestations of COVID-19

Researchers investigated the association between the increased levels of anti-platelet factor 4 antibodies and the clinical complications of COVID-19.

7 Nov 2022

Study finds no evidence of major SARS-CoV-2 spread among wild rodents

A new study published in the Emerging Infectious Diseases journal conducted a large-scale serologic survey of SARS-CoV-2 in multiple rodent species to determine the reverse transmission of SARS-Cov-2 and its establishment in wild rodents across different settings.

6 Nov 2022

Beckman Coulter Life Sciences and Pillar Biosciences Sign Application Development Agreement for the Biomek NGeniuS System

More companies around the world continue turning to Beckman Coulter Life Sciences, a global leader in laboratory automation and innovation, for their next generation sequencing (NGS) needs with the Biomek NGeniuS System.

From Beckman Coulter Life Sciences 4 Nov 2022

Assay News and Research

Proteomics approach helps identify protein signatures that can improve detection of prediabetes

Researchers demonstrate that neutralizing antibody titers wane over time in ChAdOx1, BNT162b2 and mRNA-1273 vaccinees

MicroRNAs can upregulate proteins in addition to downregulating protein production

Empty lipid nanoparticles trigger maturation and activation of antigen-presenting cells

Immunological responses against monkeypox virus concerning the 2022 outbreak

Researchers propose a deep antibody-antigen interaction algorithm to accelerate the identification of potential therapeutic antibodies

Researchers identify 55 broadly reactive monoclonal antibodies to betacoronaviruses

Study identifies novel inhibitors against SARS-CoV-2 main protease

SARS-CoV-2 activates NLRP3 inflammasome

Llusern debuts Lodestar UTI molecular diagnostic platform at Medica 2022

Study suggests anti-PF4 antibodies may play a role in the severe multiorgan disease manifestations of COVID-19

Study finds no evidence of major SARS-CoV-2 spread among wild rodents

Beckman Coulter Life Sciences and Pillar Biosciences Sign Application Development Agreement for the Biomek NGeniuS System

Accelerating Scientific Discoveries through Advanced Data Analysis Platforms

Whole-genome sequencing is a more comprehensive prenatal test l BGI Perspectives

What is the correlation between specific COVID-19 clinical characteristics and anti-SARS-CoV-2 antibody titers?

Research reveals how whole-genome sequencing may enhance detection of fetal CNS anomalies

Vimentin is an important co-receptor for SARS-CoV-2 infection

Bivalent mRNA booster broadens humoral immunity against SARS-CoV-2 Omicron subvariants

Scientists identify a broadly neutralizing antibody against all dominant SARS-CoV-2 variants

eBook: Using iPSCs models for human disease research and drug discovery eBook

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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