Tumor News and Research

RSS

Gene circuit can be used to switch on inside cancer cells and stimulate immune attack, study suggests

A new study, conducted by researchers at MIT, suggests that a recently developed synthetic gene circuit can stimulate the immune system to kill cancer cells when it identifies indications of the cancer. The gene circuit will only stimulate a therapeutic response when it identifies two particular cancer markers.

20 Oct 2017

Researchers reveal how certain nerves sustain prostate cancer growth

In a study in today's issue of Science, researchers at Albert Einstein College of Medicine, part of Montefiore Medicine, report that certain nerves sustain prostate cancer growth by triggering a switch that causes tumor vessels to proliferate.

20 Oct 2017

Small RNA molecules trigger cancer cells to commit suicide

Small RNA molecules originally developed as a tool to study gene function trigger a mechanism hidden in every cell that forces the cell to commit suicide, reports a new Northwestern Medicine study, the first to identify molecules to trigger a fail-safe mechanism that may protect us from cancer.

19 Oct 2017

UCSD researchers discover how mutant gene amplifies inflammation to fuel cancer

A human gene called p53, which is commonly known as the "guardian of the genome," is widely known to combat the formation and progression of tumors. Yet, mutant forms of p53 have been linked to more cases of human cancer than any other gene.

19 Oct 2017

New research provides insights into role of key cancer gene

New research represents a promising step towards better understanding of a key cancer gene. A long-running collaboration between researchers at the Babraham Institute, Cambridge, and the AstraZeneca IMED Biotech Unit reveals new insights into how the PTEN gene may control cell growth and behavior and how its loss contributes to the development and advancement of certain cancers.

19 Oct 2017

Scientists uncover surprising molecular link in critical cellular growth pathway

A team of scientists led by Whitehead Institute has uncovered a surprising molecular link that connects how cells regulate growth with how they sense and make available the nutrients required for growth.

19 Oct 2017

Study finds underlying causes of racial, ethnic disparities in cancer survival

Racial/ethnic disparities in cancer survival in the U.S. are well documented, but the underlying causes are not well understood. To better explain disparities, researchers examined cancer survival by racial/ethnic group for 877,662 patients diagnosed with breast, prostate, colorectal or lung cancer between 2000–2013 using California Cancer Registry data.

19 Oct 2017

Cornell study reveals how UV radiation triggers melanoma

Melanoma, a cancer of skin pigment cells called melanocytes, will strike an estimated 87,110 people in the U.S. in 2017, according to the Centers for Disease Control and Prevention. A fraction of those melanomas come from pre-existing moles, but the majority of them come from sources unknown – until now.

18 Oct 2017

Genetic diversity plays major role in evolution of drug resistance

Researchers have shown that genetic diversity plays a key role in enabling drug resistance to evolve. Scientists at the Wellcome Trust Sanger Institute and the Institute for Research on Cancer and Ageing of Nice in France, show that high genetic diversity can prime new mutations that cause drug resistance.

17 Oct 2017

Scientists receive critical funding to study treatments for three deadly cancers

Immunotherapy for leukemia patients has been nothing short of a miracle. Now scientists hope to use that science and other forms of gene therapy to tackle three of the deadliest forms of cancer: glioblastoma (brain cancer), sarcoma (bone cancer) and ovarian cancer.

17 Oct 2017

Synthetic compound targets enzyme that supports survival and dissemination of metastatic cells

Cancer can most often be successfully treated when confined to one organ. But a greater challenge lies in treating cancer that has metastasized, or spread, from the primary tumor throughout the patient's body.

17 Oct 2017

Study could pave way for more effective cancer therapies

Many tumors possess mechanisms to avoid destruction by the immune system. For instance, they misuse the natural "brakes" in the immune defense mechanism, which normally prevent an excessive immune response. Researchers at the University of Bonn have now been able to take off one of these brakes.

17 Oct 2017

Scientists discover how sugar fuels cancer growth

A nine-year research project looking at the link between sugar and cancer has led to an important breakthrough in cancer research.

17 Oct 2017

Study reveals link between cancer relapse and body’s immune system

Results from a new study conducted at the Institute of Cancer Research, London, suggests cancer cells that remain in the body after treatment, utilize the immune system of the body to wake themselves up and boost their growth.

17 Oct 2017

Study uses precision medicine approach to find effective treatments for rare cancers

For the first time, researchers have been able to identify effective treatments for patients with rare cancers by analyzing genes and proteins in their blood and tumors. In a study reported in The Oncologist, half the patients receiving these targeted treatments saw their rare cancers either stabilize, shrink or go into remission.

17 Oct 2017

Using AFM to study cell mechanics and function

My lab, broadly speaking, is interested in trying to understand interactions between cells and materials. Those could be materials that are present within living tissue or materials that we use for engineering purposes to try to do something of technological or therapeutic interest.

From Bruker Nano Surfaces and Metrology 17 Oct 2017

CHOP researchers discover key differences among gene fusions in childhood brain tumors

Researchers investigating pediatric low-grade gliomas, the most common type of brain tumor in children, have discovered key biological differences in how mutated genes combine with other genes to drive this childhood cancer.

17 Oct 2017

Scientists develop revolutionary blood screening test to diagnose breast cancer

In a potential major breakthrough in breast cancer research, scientists at the Center for Translational Cancer Research at the Helen F. Graham Cancer Center & Research Institute of Christiana Care Health System have developed a revolutionary new blood test to diagnose breast cancer.

16 Oct 2017

Factors associated with disparities in breast cancer survival studied

According to a latest study, several factors are responsible for the differences in the survival statistics of the non-elderly women with breast cancer. For example in 2012, the health reports had revealed that black women have a 43% higher risk of death when affected with breast cancer compared to their white counterparts.

16 Oct 2017

Wake Forest Baptist scientists win grant to develop more effective treatments for brain cancer

Glioblastoma is the most aggressive cancer that originates in the brain. Current therapies can slow the disease, but more often than not can't cure it.

16 Oct 2017