Small Molecules News and Research

RSS

Sheffield scientists discover that simple arthritis drug could help treat blood cancer sufferers

Blood cancer sufferers could be treated with a simple arthritis drug, scientists at the University of Sheffield have discovered.

3 Aug 2017

Vanderbilt scientists find new way to destroy microbial vampires

On July 24 Vanderbilt scientist Eric Skaar, Ph.D., MPH, summarized his group's latest paper in a tweet: "If S. aureus is going to drink our blood like a vampire, let's kill it with sunlight."

1 Aug 2017

Synthetic molecule can disrupt hunger-signaling pathway, research suggests

New research suggests that a man-made cousin of a small molecule found in olive oil can disrupt the hunger-signaling pathway.

27 Jul 2017

Research suggests novel approach for encouraging regeneration in mouse retina

Cells within an injured mouse eye can be coaxed into regenerating neurons and those new neurons appear to integrate themselves into the eye's circuitry, new research shows.

27 Jul 2017

MIT engineers design new gel coatings that may lead to better medical devices

Catheters, intravenous lines, and other types of surgical tubing are a medical necessity for managing a wide range of diseases. But a patient's experience with such devices is rarely a comfortable one.

19 Jul 2017

Salford scientists may have found simple way for designing new antibiotics

CANCER researchers in the UK may have stumbled across a solution to reverse antibiotic drug resistance and stop infections like MRSA.

12 Jul 2017

Computational analysis of open-access data points to new ways of using drugs

A research team led by scientists at UC San Francisco has developed a computational method to systematically probe massive amounts of open-access data to discover new ways to use drugs, including some that have already been approved for other uses.

12 Jul 2017

$Promising target may open door to new therapies for preventing bone fractures in diabetes patients$

Promising target may open door to new therapies for preventing bone fractures in diabetes patients

Researchers at New York University College of Dentistry have described a new target that may open the door to developing therapies for preventing bone fractures in people with type 2 diabetes.

7 Jul 2017

Scientists discover link between sugar metabolism and peroxisomal biogenesis disorders

Meeting a young patient with Zellweger syndrome, a rare, life-threatening genetic disease, started a scientific investigation that culminated with an unexpected discovery.

23 Jun 2017

New algorithm shortens drug discovery times from years to months

An algorithm developed at the Hebrew University cuts through the immense number of possible solutions to shorten drug discovery times from years to months.

22 Jun 2017

TSRI scientist and partners receive $7.2 million grant to create new RNA-based treatments for ALS

Professor Matthew Disney of the Department of Chemistry on the Florida campus of The Scripps Research Institute, together with scientists from Mayo Clinic's Florida campus and Johns Hopkins School of Medicine, has been awarded $7.2 million from the National Institute of Neurological Disorders and Stroke of The National Institutes of Health to create new RNA-based treatments for the most common form of amyotrophic lateral sclerosis (ALS), as well as a type of frontotemporal dementia (FTD).

15 Jun 2017

New research could help mitigate effects of radiation therapy

New research conducted at the University of Kansas Medical Center could make treatment for gastrointestinal cancers safer- while also helping to mitigate the dangers of nuclear accidents and terrorist attacks.

14 Jun 2017

Researchers find molecule that darkens skin without UV exposure and may protect against skin cancer

A study published in the journal Cell on June 13 has found that a class of small molecules can successfully penetrate and darken human skin samples. The drug developed in the laboratory by researchers in Boston also generates protective tans in red-haired mice.

14 Jun 2017

Vitamin A improves insulin-producing beta-cells' function, study suggests

There has been no known link between diabetes and vitamin A - until now. A new study suggests that the vitamin improves the insulin producing β-cell´s function.

13 Jun 2017

Rice scientists use magnets and nanoparticles to make vessels temporarily ‘leaky’

The endothelial cells that line blood vessels are packed tightly to keep blood inside and flowing, but scientists at Rice University and their colleagues have discovered it may be possible to selectively open gaps in those barriers just enough to let large molecules through -- and then close them again.

8 Jun 2017

Researchers develop new material that scrubs iodine from water

Researchers at Dartmouth College have developed a new material that scrubs iodine from water for the first time. The breakthrough could hold the key to cleaning radioactive waste in nuclear reactors and after nuclear accidents like the 2011 Fukushima disaster.

7 Jun 2017

Scientists create new method to make peptide stapling widely available

UK scientists have created a new method to structure peptides, which they say will be cheaper and make the process of using stapled peptides in drug discovery much more widely available.

2 Jun 2017

Therapeutic small molecules safely prevent blood clots without excessive bleeding

It may be possible to disrupt harmful blood clots in people at risk for heart attack or stroke without increasing their risk of bleeding, according to a new study published in Nature Communications.

31 May 2017

New NMR machine at TSRI’s Florida campus will help advance drug development process

The Nuclear Magnetic Resonance facility at the Florida campus of The Scripps Research Institute is becoming one of the most advanced in South Florida, thanks to a new $600,000 grant from the National Institutes of Health.

26 May 2017

Scientists report promising approach to combat influenza and improve survival

The influenza virus turns infected lung cells into factories that churn out thousands of copies of the virus to spread the infection. St. Jude Children's Research Hospital scientists have reported a promising new approach that uses an investigational cancer drug to dial down viral production and dramatically increase survival of flu-infected mice.

23 May 2017