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Smartphone fitness apps and wearable activity trackers boost physical activity levels

A new study supports the efficacy of smartphone fitness apps and wearable activity trackers at elevating levels of physical activity.

21 Dec 2020

FDA approves pembrolizumab as first-line treatment for colorectal cancer

The FDA recently approved the immunotherapy drug pembrolizumab as a first-line treatment for patients with certain types of advanced colorectal cancer. This is the 9th FDA approval supported by Stand Up To Cancer® (SU2C) research.

18 Dec 2020

Errant DNA triggers immune system response against cancer

DNA that ends up where it doesn't belong in cancer cells can unleash an immune response that makes tumors more susceptible to immunotherapy, the results of two UT Southwestern studies indicate.

17 Dec 2020

Researchers use new method to deliver anti-cancer drug to suppress tumor growth

Targeting drugs to cancer tissues is a major challenge in cancer treatment. Mesenchymal stem cells (MSCs) are known for their ability to find and target tumor cells in the body, but using MSCs for drug delivery has been tricky, because upon loading with drugs, MSCs lose their viability and migratory ability.

17 Dec 2020

Study shows rising incidence of esophageal adenocarcinoma in younger adults

Esophageal adenocarcinoma is occurring more frequently in adults under age 50, and these younger adults are more likely to be diagnosed at advanced stages.

16 Dec 2020

New combination therapy has potential to treat aggressive cancers with common mutations

Scientists have long known that therapies that target the cancer-driving MAPK pathway are only effective in a handful of cancers with specific mutations in a cancer gene called BRAF, and these cancers that initially respond to the therapy often end up developing resistance to the treatment, resulting in relapse for many patients.

14 Dec 2020

Colon lining releases hydrogen peroxide to protect the body from gut microbes

Scientists at UC Davis Health have discovered that an enzyme in the colon lining releases hydrogen peroxide (H2O2) - a known disinfecting compound- to protect the body from gut microbes.

9 Dec 2020

Modulation of oral microbiota impacts the cardiovascular benefits of sport

Exercise plays a key role in maintaining good physical and mental health throughout life. There is an increasing amount of scientific evidence that some of the immune system and metabolism benefits provided by sport are related to the thousands of millions of bacteria that colonize the digestive tract, from the mouth to the intestines, known as microbiota.

9 Dec 2020

Henry Ford Health System is first in the U.S. to perform a procedure using CG-100 intraluminal device

Henry Ford Health System is the first in the country to perform a procedure using the CG-100™ intraluminal device, which is temporarily inserted into the gastrointestinal tract and designed to reduce diverting stoma rates, and the need for an ostomy bag, in patients undergoing gastrointestinal resection procedures due to colorectal cancer treatment.

9 Dec 2020

Repair protein may prevent damage to healthy cells during cancer therapy

A key way radiation therapy and chemotherapy work is by making highly lethal double-strand breaks in the DNA of cancer cells.

9 Dec 2020

Bilayered delivery system offers new solution for treating IBS-C patients

Patients suffering from irritable bowel syndrome with constipation (IBS-C) have long needed an upgrade in treatment.

9 Dec 2020

Study examines effect of low-dose vancomycin to treat clostridium difficile infection

Clostridium difficile infection (CDI) is inflammation of the colon caused by a bacteria called clostridium difficile and is the most common cause of infectious diarrhea in hospitalized patients.

8 Dec 2020

Scientists develop new technique to measure tissue oxygen levels

Tissue oxygenation is a measure of the oxygen level in biological tissue and is a useful clinical biomarker for tissue viability. Abnormal levels may indicate the presence of conditions such as sepsis, diabetes, viral infection, or pulmonary disease, and effective monitoring is important for surgical guidance as well as medical care.

2 Dec 2020

New combination therapy may help fight antimicrobial resistance

An inexpensive, FDA-approved drug -- cholestyramine -- taken in conjunction with an antibiotic prevents the antibiotic from driving antimicrobial resistance, according to new research by scientists at Penn State and the University of Michigan. The team's findings appear today (Dec. 1) in the journal eLife.

2 Dec 2020

Cancer-killing virus developed at City of Hope activates the immune system against colon cancer

City of Hope scientists have developed a cancer-killing virus by combining the oncolytic virus CF33 with an immune checkpoint inhibitor.

1 Dec 2020

First checkpoint inhibitor vaccine shown to be safe, effective in colon cancer animal model

A study led by researchers at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute described a potential therapeutic anticancer vaccine that frees suppressed cancer-killing immune cells, enabling them to attack and destroy a tumor.

23 Nov 2020

Medicaid expansion may lead to earlier diagnosis, improved care for colon cancer patients

The Affordable Care Act's Medicaid expansion for low-income people appears to lead to earlier diagnosis of colon cancer, enhanced access to care, and improved surgical care for patients with this common cancer, researchers report in a new study.

23 Nov 2020

Food products are potential SARS-CoV-2 carriers, study finds

A team of scientists at the Shahid Beheshti University of Medical Sciences and the Food Safety Research Center in Iran has emphasized the risk of various staple food products, including meat, dairy, fruits, vegetables, and ready-to-eat foods, as potential carriers of SARS-CoV-2 transmission.

20 Nov 2020

Examining potential foodborne transmission of SARS-CoV-2 through fresh produce

To address this gap in knowledge, researchers from the Bureau of Microbial Hazards, Health Canada, and Faculty of Medicine, University of Ottawa examined the survival of human coronaviruses on the surface of fresh produce such as apples, cucumbers, and tomatoes.

18 Nov 2020

Antifungal agent Itraconazole inhibits SARS CoV-2 in vitro

Itraconazole is a broad-spectrum antifungal agent that has been shown to have some in vitro activity against SARS-CoV-2 by a team of Belgian and German researchers.

16 Nov 2020