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3D models of ovarian cancer reveal how cell’s location can affect tumor biology

Using 3-D models of ovarian cancer tumors, scientists found differences in gene activity based on where a cell is in a tumor, demonstrating how a cell's location and environment in a cancerous tumor can strongly influence which genes are active and the cell's role in the cancer's biology.

23 Jun 2023

UVA Health researcher launches an ambitious effort to improve HIV care

A UVA Health doctor is launching an ambitious effort to assess and improve HIV care for people with low incomes across the nation, a campaign that could also help prevent transmission.

23 Jun 2023

Study examines the relationship between pre-existing disease and COVID-19 outcomes in the Midwest

A study of more than three-quarters of a million Indiana COVID-19 cases is one of the first to focus on the disease in the Midwest.

22 Jun 2023

Repurposed drug effective at inhibiting a protein kinase linked to cardiac arrhythmias

Ruxolitinib, a drug that is already approved by the U.S. Food and Drug Administration (FDA) for treating certain cancers and skin conditions, is effective at inhibiting CaMKII, a protein kinase linked to cardiac arrhythmias.

21 Jun 2023

Xylazine can exacerbate the life-threatening effects of opioids, rat study shows

A new study in rats suggests that xylazine, the active ingredient in a non-opioid veterinary tranquilizer not approved for human use, can worsen the life-threatening effects of opioids.

21 Jun 2023

Newborn screening facilitates early identification of infants with severe combined immunodeficiency

Introducing widespread screening of newborns for a deadly disease called severe combined immunodeficiency, or SCID, followed by early treatment boosted the five-year survival rate of children with the disorder from 73% before the advent of screening to 87% since, researchers report.

20 Jun 2023

Eating red and white meat increases risk of cardiovascular disease

Red meat consumption linked to higher cardiovascular disease incidence globally, with stronger correlations observed in developing countries. Further exploration and longitudinal studies needed to investigate this association.

20 Jun 2023

High lipoprotein(a) levels linked to repeated heart disease events in older adults

Researchers report that high lipoprotein(a) levels were linked to repeated coronary heart disease events in older adults.

18 Jun 2023

ACQUIRE Therapy improves outcomes for children with motor disabilities

Virginia Tech researchers with the Fralin Biomedical Research Institute at VTC have demonstrated that children with a wide range of diagnoses that affect their motor function improve after receiving intensive pediatric neurorehabilitation called ACQUIRE Therapy.

16 Jun 2023

New, improved method of imaging and analyzing biological samples

There are various ways to image biological samples on a microscopic level, and each has its own pros and cons.

16 Jun 2023

New method offers insights into mechanisms of staphylococcal pathogenesis

Nearly one in three people globally unknowingly carries Golden staph, or Staphylococcus aureus, in their nose or on their skin. While the bacterium is harmless to most, it can lead to serious infection and even death if it enters the bloodstream through a cut, surgical wound or catheter.

16 Jun 2023

Promising emerging treatment for cardiac arrest patients yields similar results to targeted standard care

A promising emerging treatment (hypercapnia) for comatose adult cardiac arrest patients has been found to yield similar results to current treatment, in a new study published today in the prestigious medical journal New England Journal of Medicine.

15 Jun 2023

Mapping the evolutionary timeline and population distribution of E. coli’s protective outer capsule

In a new study, published today (15 June) in Nature Communications, a multi-centre team led by the Wellcome Sanger Institute, the University of Oslo, Imperial College London and UCL, has mapped for the first time the evolutionary timeline and population distribution of Escherichia coli’s protective outer capsule, which is responsible for the bacterium’s virulence.

15 Jun 2023

Males are significantly more vulnerable than females to overdose deaths

Men were significantly more vulnerable than women to overdose deaths involving opioid and stimulant drugs in 2020-2021, according to a new study analyzing death records data from across the United States. The study found that men had a 2–3 times greater rate of overdose mortality from opioids (like fentanyl and heroin) and psychostimulants (like methamphetamine and cocaine).

15 Jun 2023

Phenotyping identifies long COVID subtypes

Researchers discuss the phenotypes associated with long COVID inflammation.

14 Jun 2023

Inflammation regulating gene also plays a key role in maintaining normal blood-sugar levels, study shows

A study led by researchers at the Garvan Institute of Medical Research shows for the first time how a gene called RELA, known to regulate inflammation, also plays an essential role in maintaining normal blood-sugar levels.

14 Jun 2023

Race may account for the disparity in pharmacological treatment of insomnia

In one of the first studies to investigate racial disparities in the pharmacologic treatment of insomnia, researchers from Regenstrief Institute and Indiana University report that patients belonging to racial minority groups were significantly less likely to be prescribed medication following diagnosis of insomnia than White patients.

14 Jun 2023

Medical Research News and Research

3D models of ovarian cancer reveal how cell’s location can affect tumor biology

UVA Health researcher launches an ambitious effort to improve HIV care

Study examines the relationship between pre-existing disease and COVID-19 outcomes in the Midwest

Repurposed drug effective at inhibiting a protein kinase linked to cardiac arrhythmias

Xylazine can exacerbate the life-threatening effects of opioids, rat study shows

Newborn screening facilitates early identification of infants with severe combined immunodeficiency

Eating red and white meat increases risk of cardiovascular disease

High lipoprotein(a) levels linked to repeated heart disease events in older adults

ACQUIRE Therapy improves outcomes for children with motor disabilities

New, improved method of imaging and analyzing biological samples

New method offers insights into mechanisms of staphylococcal pathogenesis

Promising emerging treatment for cardiac arrest patients yields similar results to targeted standard care

Mapping the evolutionary timeline and population distribution of E. coli’s protective outer capsule

Males are significantly more vulnerable than females to overdose deaths

Phenotyping identifies long COVID subtypes

Inflammation regulating gene also plays a key role in maintaining normal blood-sugar levels, study shows

Race may account for the disparity in pharmacological treatment of insomnia

New process for creating a “meta-cell overcomes the challenges of studying single-cell secrets

Using heart and lung stem cells to better understand how COVID-19 impacts different organs

Study: Only 1 in 4 addiction treatment facilities caring for U.S. adolescents offer buprenorphine

eBook: Advancing neurodegenerative research with iPSC-derived microglia models eBook

Shaping the Future of Neuroscience: A Conversation with Atlas Antibodies on the MolBoolean™ and the Impact of SfN 2024

How the Arts Reshape Brain Function: Susan Magsamen on the Future of Neuroaesthetics

Inside the Alzheimer's Association: Dr. Heather Snyder on Driving Research and Collaboration

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