Staphylococcus aureus News and Research

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Staphylococcus aureus is a spherical bacterium (coccus) which on microscopic examination appears in pairs, short chains, or bunched, grape-like clusters. These organisms are Gram-positive. Some strains are capable of producing a highly heat-stable protein toxin that causes illness in humans.

Chlorhexidine bathing protects vulnerable hospital patients

Bathing hospital patients with chlorhexidine-impregnated washcloths reduces the risk for them acquiring multidrug-resistant organisms and developing bloodsteam infections, show study findings.

7 Feb 2013

Researchers discover gene that causes MRSA infection to linger on skin longer than other strains

In the last decade, a new strain of MRSA has emerged that can spread beyond hospital walls, putting everyone at risk of contracting the dangerous bacterial infection. This particular strain of MRSA - known as USA300 - contains a chunk of genes not shared by any other strains, though it is unclear how this unique genetic material enables the bacteria to survive and persist in the community.

4 Feb 2013

Top ten tips for keeping bed bugs at bay

Bed bugs are on the rise and $1,000 per day ordinances are being suggested in cities like Chicago to enforce combat of the pests. "Know thy enemy," says Jorge Parada, MD, medical director, infection control, Loyola University Health System. "There are lots of myths out there about bed bugs and people may be getting caught up over nothing."

30 Jan 2013

Researchers identify mechanism by which S. aureus colonises nasal passages

29 Jan 2013

Breathprints identify lung infections in mice

Researchers working with a mouse model have developed a technique for creating “breathprints” that flag up whether or not the animals have a lung infection.

28 Jan 2013

Breathprints identify lung infections in mice

Researchers working with a mouse model have developed a technique for creating “breathprints” that flag up whether or not the animals have a lung infection.

25 Jan 2013

Strong link between mortality and reduced innate immune responsiveness in critically ill patients

Investigators from 15 children's medical centers, including Nationwide Children's Hospital, observed and evaluated critically ill children with influenza to evaluate the relationships between levels of systemic inflammation, immune function and likelihood to die from the illness. The study appears in the January issue of Critical Care Medicine.

23 Jan 2013

Suppression of immune system function can occur in influenza patients

22 Jan 2013

Researchers use electrokinetic patterning to separate particles and microbes by size

Researchers have demonstrated a new technology that combines a laser and electric fields to create tiny centrifuge-like whirlpools to separate particles and microbes by size, a potential lab-on-a-chip system for medicine and research.

9 Jan 2013

New compound restores health of mice with MRSA infection

Researchers have discovered a new compound that restores the health of mice infected with methicillin-resistant Staphylococcus aureus (MRSA), an otherwise dangerous bacterial infection. The new compound targets an enzyme not found in human cells but which is essential to bacterial survival.

8 Jan 2013

Study identifies mechanism by which bacterium S. aureus colonizes nasal passages

A collaboration between researchers at the School of Biochemistry and Immunology and the Department of Microbiology at Trinity College Dublin has identified a mechanism by which the bacterium Staphylococcus aureus (S. aureus) colonizes our nasal passages. The study, published today in the Open Access journal PLOS Pathogens, shows for the first time that a protein located on the bacterial surface called clumping factor B (ClfB) has high affinity for the skin protein loricrin.

29 Dec 2012

Pergamum’s DPK-060 Phase II trial on acute external otitis meets primary end-point

Pergamum AB announced today that the primary end-point was met in the randomized Phase II trial of DPK-060 for treatment of acute external otitis.

21 Dec 2012

Study suggests that existing HIV drug could be a potential therapy for Staph infections

A new study by NYU School of Medicine researchers suggests that an existing HIV drug called maraviroc could be a potential therapy for Staphylococcus aureus, a notorious and deadly pathogen linked to hundreds of thousands of hospitalizations each year.

15 Dec 2012

NovaDigm announces data from NDV-3 vaccine Phase 1 study on Candida and Staph infections

NovaDigm Therapeutics, a company developing innovative vaccines for fungal and bacterial infections, today announced the publication of data from its first-in-human Phase 1 study of its NDV-3 vaccine program in the journal Vaccine.

13 Dec 2012

Contact precautions reduce number of visits by healthcare workers and outside visitors

The prevention and control of healthcare-associated infections (HAIs) can help reduce patient morbidity and mortality, but a common prevention effort for patients with hard to treat infections known as contact precautions, can have positive and negative impacts on patient care.

12 Dec 2012

Top-line results from Durata Therapeutics’ dalbavancin Phase 3 study on ABSSSI

Durata Therapeutics, Inc. today announced preliminary, top-line results for its DISCOVER 1 ("Dalbavancin for Infections of the Skin COmpared to Vancomycin at an Early Response") Phase 3 study of dalbavancin, which is under investigation for the treatment of acute bacterial skin and skin structure infections (ABSSSI) caused by susceptible gram-positive bacteria, including MRSA (methicillin resistant Staphylococcus aureus).

11 Dec 2012

Throat swabs should be included in S. aureus screening programs

Performing throat swabs, in addition to nasal swabs, in Staphylococcus aureus screening programs may improve rates of detection, suggest study findings.

10 Dec 2012

FDA designates two of Cubist’s Phase 3 antibiotic candidates

Cubist Pharmaceuticals, Inc. today announced that the U.S. Food and Drug Administration (FDA) has designated two of the company's Phase 3 antibiotic candidates, CXA-201 (ceftolozane/tazobactam) and CB-315, as Qualified Infectious Disease Products (QIDP).

6 Dec 2012

Johns Hopkins focuses on MRSA, motherhood in November-December 2012 research news brief

Johns Hopkins Nursing researchers focus on MRSA, motherhood, hospital stress, intimate partner violence, and more in the November-December 2012 research news brief.

6 Dec 2012

Metalloacid surfaces may be answer to hospital-acquired infections

Coating surfaces in metalloacids may help control the spread of hospital-acquired infections, suggest study findings.

14 Nov 2012

Staphylococcus aureus News and Research

Further Reading

Chlorhexidine bathing protects vulnerable hospital patients

Researchers discover gene that causes MRSA infection to linger on skin longer than other strains

Top ten tips for keeping bed bugs at bay

Researchers identify mechanism by which S. aureus colonises nasal passages

Breathprints identify lung infections in mice

Breathprints identify lung infections in mice

Strong link between mortality and reduced innate immune responsiveness in critically ill patients

Suppression of immune system function can occur in influenza patients

Researchers use electrokinetic patterning to separate particles and microbes by size

New compound restores health of mice with MRSA infection

Study identifies mechanism by which bacterium S. aureus colonizes nasal passages

Pergamum’s DPK-060 Phase II trial on acute external otitis meets primary end-point

Study suggests that existing HIV drug could be a potential therapy for Staph infections

NovaDigm announces data from NDV-3 vaccine Phase 1 study on Candida and Staph infections

Contact precautions reduce number of visits by healthcare workers and outside visitors

Top-line results from Durata Therapeutics’ dalbavancin Phase 3 study on ABSSSI

Throat swabs should be included in S. aureus screening programs

FDA designates two of Cubist’s Phase 3 antibiotic candidates

Johns Hopkins focuses on MRSA, motherhood in November-December 2012 research news brief

Metalloacid surfaces may be answer to hospital-acquired infections

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