Major Depressive Disorder News and Research

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Major Depressive Disorder (MDD) is a psychiatric condition characterized by depressed mood or anhedonia (significant loss of interest or pleasure). The condition affects more than 15.7 million adults and approximately 3 million adolescents (aged 13 to 17 years) in the USA each year.

UT Southwestern investigators test groundbreaking depression research in real-world setting

UT Southwestern Medical Center psychiatry researchers have taken what they learned from their groundbreaking research on treating depression and are applying it to real-world clinical settings.

15 Jun 2008

Antidepressants do work in depression while evidence for cognitive behavioural yherapy is poorer say experts

A new revision of clinical guidelines to help doctors manage patients with depression has challenged the rationale behind the UK government's policy of rolling out of cognitive behavioural therapy (CBT) for milder depression.

7 May 2008

Nurse care for schizophrenia patients

Drug and psychosocial interventions for the symptoms of schizophrenic disorders contribute to a lower incidence and prevalence of schizophrenia. Nurses will be able to offer better care through the use of nursing models and theories in the care of Schizophrenics.

6 May 2008

Depression in seniors linked to low levels of vitamin D

Researchers in Holland have found that older people with low blood levels of vitamin D and high blood levels of the parathyroid hormone are more likely to be depressed.

6 May 2008

Low blood levels of vitamin D may be associated with depression in seniors

Older adults with low blood levels of vitamin D and high blood levels of a hormone secreted by the parathyroid glands may have a higher risk of depression, according to a report in the May issue of Archives of General Psychiatry.

5 May 2008

Results of St. Jude Medical deep brain stimulation study presented at APA meeting

St. Jude Medical, Inc. today announced pilot study results from the first multi-center study investigating deep brain stimulation (DBS) of Brodmann Area 25 for major depressive disorder.

5 May 2008

Brain tumor surgery, depression and survival

Depression is one of the most common psychiatric disorders in the world today. It is estimated that in any given year, 5 to 9 percent of the US population is clinically depressed. Studies have shown that depression negatively affects the immunological system, alters the body's response to malignancy, and may influence behavioral factors that impact recovery from disease

29 Apr 2008

NIH study reveals incidence, precursors and psychiatric sequelae of major psychiatric disorders

A new study by the National Institute on Alcohol Abuse and Alcoholism (NIAAA) presents results on the first onset of substance use disorders (i.e., alcohol and drug abuse and dependence) and major mood and anxiety disorders, based on Wave 2 of the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC).

22 Apr 2008

Omega-3 fatty acids for bipolar disorder

Despite intriguing findings that omega-3 fatty acid supplements could alleviate depression symptoms, there is still not enough evidence to say whether omega-3s are useful treatments for people with bipolar disorder, according to a review of recent studies.

22 Apr 2008

St. Jude Medical awarded U.S. patent for neurostimulation therapy for depression

St. Jude Medical, Inc. has announced it has been awarded a patent from the U.S. Patent and Trademark Office for treating depression using neurostimulation therapy in an area of the brain known as Brodmann Area 25.

21 Apr 2008

Link found between insomnia and depression in young adults

A study published in the April 1 issue of the journal SLEEP confirms the persistent nature of insomnia and the increased risk of subsequent depression among individuals with insomnia.

2 Apr 2008

When your antidepressants don't work

should you switch to a different medication from the same class or should you try an antidepressant medication that has a different mechanism of action?

26 Mar 2008

Severe West Nile infection could lead to lifetime of symptoms

Most people who suffer severe infection with West Nile virus still experience symptoms years after infection and many may continue to experience these symptoms for the rest of their lives according to research presented (March 17) at the 2008 International Conference on Emerging Infectious Diseases in Atlanta, Georgia.

18 Mar 2008

Does depression lead to stroke?

Psychological distress, but not depression, may increase the risk of stroke, according to a study published in the March 4, 2008, issue of Neurology, the medical journal of the American Academy of Neurology.

4 Mar 2008

Clinical depression raises risk of death for heart attack patients years after attack

Depressed heart attack patients have a higher risk for sudden death in the months following a heart attack.

4 Mar 2008

FDA approves PRISTIQ for the treatment of adult patients with major depressive disorder

Wyeth Pharmaceuticals, a division of Wyeth, has announced that the U.S. Food and Drug Administration (FDA) has approved PRISTIQ (desvenlafaxine), a structurally novel, once-daily serotonin-norepinephrine reuptake inhibitor (SNRI), to treat adult patients with major depressive disorder (MDD).

3 Mar 2008

AstraZeneca submits sNDA for SEROQUEL XR for treatment of major depressive disorder

AstraZeneca has announced the submission of a supplemental New Drug Application (sNDA) to the U.S. Food and Drug Administration (FDA) for once- daily SEROQUEL XR (quetiapine fumarate) Extended-Release Tablets to seek approval for the treatment of major depressive disorder (MDD) as monotherapy, adjunct therapy, and maintenance therapy in adult patients.

1 Mar 2008

Antidepressants only benefit some

A new study published today in PLoS Medicine suggests that antidepressants only benefit some, very severely depressed patients.

27 Feb 2008

Depressed teens respond well to combination therapy

More than half of teenagers with the most debilitating forms of depression that do not respond to treatment with selective serotonin reuptake inhibitors (SSRIs) show improvement after switching to a different medication combined with cognitive behavioral therapy, researchers at UT Southwestern Medical Center and their colleagues in a multicenter study have found

27 Feb 2008

Adding therapy helps adolescents with depression not responding to SSRIs

For adolescents with depression not responding to an initial treatment with a selective serotonin reuptake inhibitor (SSRI; a class of antidepressant drugs), switching medications and adding cognitive behavioral therapy resulted in an improvement in symptoms, compared to just changing medications, according to a study in the February 27 issue of JAMA: The Journal of the American Medical Association.

27 Feb 2008

Major Depressive Disorder News and Research

Further Reading

UT Southwestern investigators test groundbreaking depression research in real-world setting

Antidepressants do work in depression while evidence for cognitive behavioural yherapy is poorer say experts

Nurse care for schizophrenia patients

Depression in seniors linked to low levels of vitamin D

Low blood levels of vitamin D may be associated with depression in seniors

Results of St. Jude Medical deep brain stimulation study presented at APA meeting

Brain tumor surgery, depression and survival

NIH study reveals incidence, precursors and psychiatric sequelae of major psychiatric disorders

Omega-3 fatty acids for bipolar disorder

St. Jude Medical awarded U.S. patent for neurostimulation therapy for depression

Link found between insomnia and depression in young adults

When your antidepressants don't work

Severe West Nile infection could lead to lifetime of symptoms

Does depression lead to stroke?

Clinical depression raises risk of death for heart attack patients years after attack

FDA approves PRISTIQ for the treatment of adult patients with major depressive disorder

AstraZeneca submits sNDA for SEROQUEL XR for treatment of major depressive disorder

Antidepressants only benefit some

Depressed teens respond well to combination therapy

Adding therapy helps adolescents with depression not responding to SSRIs

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