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Researchers identify a genetic defect in alveolar macrophages that causes lung disease

New discovery on the causes of PAP lung disease can also offer solutions for treating obesity and heart disease. The research group of Associate Professor Alexander Mildner at the University of Turku, Finland, identified a genetic defect that causes the accumulation of lipids in the pulmonary alveoli.

19 Sep 2022

Smartphones can detect blood oxygen saturation levels down to 70%, study shows

First, pause and take a deep breath. When we breathe in, our lungs fill with oxygen, which is distributed to our red blood cells for transportation throughout our bodies. Our bodies need a lot of oxygen to function, and healthy people have at least 95% oxygen saturation all the time.

19 Sep 2022

Research examines the roles of cytokines during SARS-CoV-2 infection in rhesus macaques

In a recent study posted to the bioRxiv* preprint server, researchers in the United States assessed the role of two cytokines, interferon-gamma (IFN-γ) and interleukin-10 (IL-10), in regulating immune cell responses and inflammation early during severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in rhesus macaques.

18 Sep 2022

An improved COVID-19 vaccine shows promise against Omicron in experimental models

In a recent study published in the journal Science Translational Medicine, researchers in the United States designed a bivalent coronavirus disease 2019 (COVID-19) vaccine on the messenger ribonucleic acid (mRNA) platform.

18 Sep 2022

Research reveals pivotal role of C/EBPb in the development of alveolar macrophages

If a secretion in the lungs’ alveoli is not cleared regularly, breathing difficulties can develop. In a study published in Science Immunology, a team led by Alexander Mildner and Achim Leutz has now explained the pivotal role of the transcription factor C/EBPb in this process.

16 Sep 2022

Lab experiments add further evidence to the bradykinin storm theory of COVID-19’s viral pathogenesis

A new paper published in Nature Communications adds further evidence to the bradykinin storm theory of COVID-19's viral pathogenesis -; a theory that was posited two years ago by a team of researchers at the Department of Energy's Oak Ridge National Laboratory.

16 Sep 2022

One year later, 40% of patients with COVID pneumonia still had lung problems

A recent study published in the journal Respiratory Research found impaired lung function and dyspnea amongst severe COVID-19 pneumonia survivors one year post-infection. Meanwhile, many COVID-19 patients developed fibrotic-like sequelae as an aftermath of the infection-associated mild or severe pneumonia.

15 Sep 2022

Discovery of 380-million-year-old heart sheds new light on the evolution of our bodies

Researchers have discovered a 380-million-year-old heart – the oldest ever found – alongside a separate fossilized stomach, intestine and liver in an ancient jawed fish, shedding new light on the evolution of our own bodies.

15 Sep 2022

New immunotherapy approach may lead to an effective treatment for fibrosis

Chronic diseases often lead to fibrosis, a condition in which organ tissue suffers from excessive scarring.

15 Sep 2022

What is the effect of the Omicron variant on olfaction?

A new study discusses the effect of the Omicron variant of the virus on the olfactory system in humans.

15 Sep 2022

Customized bivalent mRNA COVID boosters protect against BA.5 Omicron variant

In a recent study posted to the bioRxiv* pre-print server, researchers from Washington University School of Medicine, Moderna, Inc, and the U.S. National Institutes of Health tested two bivalent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines based on the messenger ribonucleic acid (mRNA) platform.

14 Sep 2022

Neisseria species are linked to worsening bronchiectasis in patients, study shows

A team of international scientists led by the Nanyang Technological University, Singapore (NTU Singapore) has discovered that Neisseria - a genus of bacteria that lives in the human body - is not as harmless as previously thought, and can cause infections in patients with bronchiectasis, asthma, and chronic obstructive pulmonary disease (COPD).

14 Sep 2022

Air pollution may trigger arrhythmias in healthy adolescents

Breathing particulate matter (i.e., tiny particles suspended in the air) air pollution may trigger irregular heart rhythms (arrhythmias) in healthy teenagers, according to new research published today in the Journal of the American Heart Association, an open access, peer-reviewed journal of the American Heart Association.

14 Sep 2022

What is the impact of COVID-19 treatments targeting intracellular Neu1?

In a new study, researchers assessed the impact of targeting intracellular Neu1 on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.

14 Sep 2022

Intranasal administration of liposomes displaying SARS-CoV-2 antigen induces mucosal immunity

A new study suggested that an intranasal severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine induced mucosal immune responses in mice.

14 Sep 2022

First-of-its-kind messenger RNA therapy developed for ovarian cancer, cachexia

Researchers at Oregon State University and Oregon Health & Science University have developed a promising, first-of-its-kind messenger RNA therapy for ovarian cancer as well as cachexia, a muscle-wasting condition associated with cancer and other chronic illnesses.

13 Sep 2022

Lungs News and Research

Researchers identify a genetic defect in alveolar macrophages that causes lung disease

Smartphones can detect blood oxygen saturation levels down to 70%, study shows

Research examines the roles of cytokines during SARS-CoV-2 infection in rhesus macaques

An improved COVID-19 vaccine shows promise against Omicron in experimental models

Research reveals pivotal role of C/EBPb in the development of alveolar macrophages

Lab experiments add further evidence to the bradykinin storm theory of COVID-19’s viral pathogenesis

One year later, 40% of patients with COVID pneumonia still had lung problems

Discovery of 380-million-year-old heart sheds new light on the evolution of our bodies

New immunotherapy approach may lead to an effective treatment for fibrosis

What is the effect of the Omicron variant on olfaction?

Customized bivalent mRNA COVID boosters protect against BA.5 Omicron variant

Neisseria species are linked to worsening bronchiectasis in patients, study shows

Air pollution may trigger arrhythmias in healthy adolescents

What is the impact of COVID-19 treatments targeting intracellular Neu1?

Intranasal administration of liposomes displaying SARS-CoV-2 antigen induces mucosal immunity

First-of-its-kind messenger RNA therapy developed for ovarian cancer, cachexia

AI system can quickly and automatically evaluate chest X-rays for TB

Study identifies mechanism behind 'cytokine storm' in COVID-19 patient lungs

Study uncovers how air pollution can trigger lung cancer in individuals with no history of smoking

Saline nasal irrigation after COVID-19 diagnosis reduces hospitalization

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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