Bioinformatics News and Research

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Bioinformatics is the application of information techniques for the storage, retrieval, and analysis of large quantities of biological data.

Parkinson's disease may affect brain cells before birth

People who develop Parkinson's disease before age 50 may have been born with disordered brain cells that went undetected for decades, according to new Cedars-Sinai research. The research points to a drug that potentially might help correct these disease processes.

27 Jan 2020

Noscendo and UKB partner to expand DISQVER platform in the field of microbial resistances

Noscendo GmbH and the University Hospital Bonn today announced the successful signing of a cooperative agreement with the Institute for Hygiene and Public Health at the UKB, working towards expansion of the proprietary and CE-certified diagnostic platform DISQVER in the field of microbial resistances.

27 Jan 2020

International researchers confirm potential inhibitors to combat glioblastoma

After diagnosis, only thirty percent of glioblastoma (an aggressive brain cancer) patients have survived more than two years.

21 Jan 2020

Research team identifies new roles for Huntington's Disease protein

A Duke University research team has identified a new function of a gene called huntingtin, a mutation of which underlies the progressive neurodegenerative disorder known as Huntington's Disease.

21 Jan 2020

Scientists break new ground with animal-free antibodies for diphtheria

A project taking the first steps towards ending the use of horses to treat diphtheria has succeeded.

21 Jan 2020

A protein found in ovarian cancer may contribute to neurodegeneration in Alzheimer's disease

Houston Methodist scientists identified a protein found in ovarian cancer that may contribute to declining brain function and Alzheimer's disease, by combining computational methods and lab research.

13 Jan 2020

Researchers develop new approach to better understand protein interaction in the body

Proteins are often called the working molecules of the human body. A typical body has more than 20,000 different types of proteins, each of which are involved in many functions essential to human life.

10 Jan 2020

Study: Environment changes can impact stability landscape of the gut microbial community

Your fingerprints stay the same all your life. But what about the "fingerprint" of microbial strains that are shared in the guts of childhood twins?

9 Jan 2020

Research project leverages big data to close the gap on cognitive decline and healthy aging

A new research project at the University of Arizona Center for Innovation in Brain Science will apply a big-data approach, using bioinformatics and computational modeling, to better understand the systems biology of Alzheimer's and other neurodegenerative diseases.

8 Jan 2020

A new deep learning approach to predict disease-associated mutations

During the past years, artificial intelligence (AI) -- the capability of a machine to mimic human behavior -- has become a key player in high-techs like drug development projects.

28 Dec 2019

CD4 T cells are not to be blamed for pushing dengue fever from bad to worse

No one knows what makes a mild dengue viral infection morph into a severe and sometimes deadly dengue hemorrhagic fever/dengue shock syndrome.

26 Dec 2019

New, faster and cheaper method to uncover genetic variants in single cells

Researchers led by the European Molecular Biology Laboratory in Heidelberg and the Center for Bioinformatics at Saarland University in Saarbrücken, Germany, have developed a cheaper and faster method to check for genetic differences in individual cells, which outperforms existing techniques with respect to the information received.

23 Dec 2019

Researchers develop powerful computer algorithm for large-scale genomic analysis

Haplotypes are a set of genetic variations that, located side by side on the same chromosome, are transmitted in a single group to the next generation. Their examination makes it possible to understand the heritability of certain complex traits, such as the risk of developing a disease.

20 Dec 2019

Combined datasets can expedite the discovery and development of new cancer drugs

A comprehensive map of genes necessary for cancer survival is one step closer, following the validation of the two largest CRISPR-Cas9 genetic screens in 725 cancer models, across 25 different cancer types.

20 Dec 2019

New method identifies harmful bacteria in less time and at a very low cost

A new bacterial identification method, called ON-rep-seq, examines selective, strain-specific fragments of the bacterial genome, allowing the generation of results that earlier required DNA sequencing of the entire bacterial genome or tedious approaches like pulsed field gel electrophoresis, which previously has been the golden the standard for strain-level typing of microorganisms.

18 Dec 2019

Using math equations to detect and forecast liver cancer risk

The use of mathematical modeling in the study of biological systems has become a challenging and rewarding field of research as it yields many unknown pieces of information. A new study published online on December 16, 2019, in the journal Proceedings of the National Academy of Science (PNAS).

17 Dec 2019

Researchers identify novel genetic signature with prognostic value for certain breast cancers

Researchers have identified a genetic signature with prognostic value for certain kinds of breast cancer. The discovery also contributes to a better understanding of the molecular mechanisms of pathological angiogenesis, the aberrant proliferation of blood vessels that occurs during cancer and other diseases.

17 Dec 2019

Lifestyle-related blood lipid profile better predicts type 2 diabetes risk

Using lipidomics, a technique that measures the composition of blood lipids at a molecular level, and machine learning, researchers at Lund University in Sweden have identified a blood lipid profile that improves the possibility to assess, several years in advance, the risk of developing type 2 diabetes.

17 Dec 2019

Extrachromosomal circular DNA can contribute to cancer development in children

Cancer development is associated with the gradual accumulation of DNA defects over time. Thus, cancer is considered an age-related disease.

17 Dec 2019

Houston Methodist scientist proposes new combination treatment for Ewing sarcoma

Ewing sarcoma, an aggressive tumor that commonly affects bones in adolescents and young adults, is diagnosed in about 225 American children and teens every year, accounting for about 1 percent of pediatric cancers.

16 Dec 2019

Bioinformatics News and Research

Further Reading

Parkinson's disease may affect brain cells before birth

Noscendo and UKB partner to expand DISQVER platform in the field of microbial resistances

International researchers confirm potential inhibitors to combat glioblastoma

Research team identifies new roles for Huntington's Disease protein

Scientists break new ground with animal-free antibodies for diphtheria

A protein found in ovarian cancer may contribute to neurodegeneration in Alzheimer's disease

Researchers develop new approach to better understand protein interaction in the body

Study: Environment changes can impact stability landscape of the gut microbial community

Research project leverages big data to close the gap on cognitive decline and healthy aging

A new deep learning approach to predict disease-associated mutations

CD4 T cells are not to be blamed for pushing dengue fever from bad to worse

New, faster and cheaper method to uncover genetic variants in single cells

Researchers develop powerful computer algorithm for large-scale genomic analysis

Combined datasets can expedite the discovery and development of new cancer drugs

New method identifies harmful bacteria in less time and at a very low cost

Using math equations to detect and forecast liver cancer risk

Researchers identify novel genetic signature with prognostic value for certain breast cancers

Lifestyle-related blood lipid profile better predicts type 2 diabetes risk

Extrachromosomal circular DNA can contribute to cancer development in children

Houston Methodist scientist proposes new combination treatment for Ewing sarcoma

eBook: A guide to RNA sequencing eBook

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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