Nephrology News and Research

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Nephrology is a branch of internal medicine and pediatrics dealing with the study of the function and diseases of the kidney.

RAAS inhibitors are safe to use in COVID-19 patients, study shows

The coronavirus disease (COVID-19) is a novel illness that has spread across the globe in just five months. Caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the viral infection binds to the angiotensin-converting enzyme 2 (ACE2) to enter and invade cells.

21 May 2020

Next-gen nano technologies set to transform the medical industry

Next-gen nano technologies that can prevent infection and diagnose disease are set to transform the medical industry as this important UniSA research is awarded more than $2 million dollars under the National Health and Medical Research Council 2021 Investigator Grants.

21 May 2020

Scientist has ‘invisible enemy’ in sights with microscopic portraits of coronavirus

From her laboratory in the far western reaches of Montana, Elizabeth Fischer is trying to help people see what they're up against in COVID-19.

21 May 2020

Study focuses on COVID-19 patients with inflammatory rheumatic diseases

The ongoing COVID-19 pandemic has caused nearly five million cases and over 327,000 deaths worldwide. The signs and symptoms of this disease are varied, although there are typical features which assist diagnosis.

20 May 2020

Drug combination could eliminate side effects of largely abandoned diabetes treatment

A new UT Southwestern study shows how an effective but largely abandoned treatment for Type 2 diabetes could be used again in combination with another drug to eliminate problematic side effects.

20 May 2020

MicroRNAs in maternal blood may predict development of preeclampsia

Small non-coding RNA molecules, called microRNAs (miRNAs), found and measured in the blood plasma of asymptomatic pregnant women may predict development of preeclampsia, a condition characterized by high blood pressure and abnormal kidney function that affects roughly 5 to 8 percent of all pregnancies.

20 May 2020

Fewer traffic collisions during shutdown means longer waits for organ donations

On Day Two of the San Francisco Bay Area's stay-at-home orders in March, Nohemi Jimenez got into her car in San Pablo, California, waved goodbye to her 3-year-old son and drove to her regular Wednesday dialysis appointment.

19 May 2020

Researchers are developing a diagnostic test that predicts the advanced stages of COVID-19 patients

A research team from the University of Valencia, led by Professor Juan Saus from the Department of Biochemistry and Molecular Biology, is developing a project to provide the healthcare system with a diagnostic test that anticipates the entry into advanced stages of patients with COVID-19 and a scalable oral treatment for the disease.

19 May 2020

Novel insights on SARS-CoV-2 cell entry may inform further vaccine and treatment development

A research group from Harvard Medical School reported two cryo-electron microscopy structures derived from a single preparation of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) protein in their paper available on the preprint server bioRxiv. Understanding the nuances of prefusion and postfusion conformations shed light on viral cell entry and may, in turn, guide the development of vaccines and drugs.

18 May 2020

New and unexplored angle in the binding of SARS-CoV-2 to host cells

Researchers in the Netherlands, Cuba, and Italy have made important discoveries about the carbohydrate-mediated binding of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein to host cell lectin receptors and host lung microbiota.

17 May 2020

Sociodemographic factors linked to positive SARS-CoV-2 test result in primary care

Older age, being male, deprivation, living in a densely populated area, ethnicity, obesity, and chronic kidney disease are associated with a positive test for COVID-19, according to results from 3,802 people tested for SARS-CoV-2 (including 587 positive tests) in the UK.

15 May 2020

High DPP3 concentration in the blood predicts multiple organ failure in burn patients

Diagnostics company SphingoTec GmbH ("sphingotec") and 4TEEN4 Pharmaceuticals GmbH ("4TEEN4") announced today the publication of new data showing that high blood levels of Dipeptidyl Peptidase 3 (DPP3) are indicating upcoming multiple organ failure and mortality risk in burn patients.

15 May 2020

Novel study tracks symptomatic and asymptomatic COVID-19 spread in pediatric dialysis unit

As COVID-19 continues its sweep around the globe, dialysis units have continued to be hotspots for the virus' spread. Researchers at Indiana University School of Medicine hope to combat that threat, through a novel study published May 14, 2020 in JAMA.

14 May 2020

ACTG initiates clinical trial to evaluate treatment for COVID-19

The AIDS Clinical Trials Group, the world's largest and longest established HIV research network, today announced the initiation of ACTG 5395, a clinical trial to evaluate whether the drug combination hydroxychloroquine and azithromycin can prevent hospitalization and death from COVID-19 (which is caused by infection with the virus SARS-CoV-2).

14 May 2020

Anti-inflammatory drug may improve respiratory function in some severe COVID-19 cases

A small study in Greece found that the clinically approved anti-inflammatory drug anakinra, used to treat rheumatoid arthritis, improved respiratory function in patients with severe coronavirus disease 2019 (COVID-19).

14 May 2020

Does HIV infection increase the severity of COVID-19?

A new study by researchers at the New York University Grossman School of Medicine and published on the preprint server medRxiv* in May 2020 reports that being infected with HIV at the time of acquiring COVID-19 does not significantly increase the severity of illness or the risk of complications.

13 May 2020

Researchers urge Ireland government to change recommendations for vitamin D supplements

A new publication from Dr Eamon Laird and Professor Rose Anne Kenny, School of Medicine, and the Irish Longitudinal Study on Ageing (TILDA), in collaboration with Professor Jon Rhodes at University of Liverpool, highlights the association between vitamin D levels and mortality from COVID-19.

13 May 2020

Study shows why older individuals are vulnerable to COVID-19

A group of tiny RNA that should attack the virus causing COVID-19 when it tries to infect the body are diminished with age and chronic health problems, a decrease that likely helps explain why older individuals and those with preexisting medical conditions are vulnerable populations, investigators report.

13 May 2020

Analysis of single-cell data indicates that SARS-Cov-2 targets many cell types

Before it can sicken people, the new coronavirus must first sneak into their cells. But not any cell will do. The virus can enter only those with a certain combination of molecules on their surfaces.

13 May 2020

Experimental two-in-one diabetes shot provides better blood sugar control

The number of people with diabetes has increased from 108 million in 1980 to a staggering 422 million in 2014. In 2016, an estimated 1.6 million deaths were directly caused by diabetes, while another 2.2 million deaths were tied to high blood glucose.

12 May 2020

Nephrology News and Research

Further Reading

RAAS inhibitors are safe to use in COVID-19 patients, study shows

Next-gen nano technologies set to transform the medical industry

Scientist has ‘invisible enemy’ in sights with microscopic portraits of coronavirus

Study focuses on COVID-19 patients with inflammatory rheumatic diseases

Drug combination could eliminate side effects of largely abandoned diabetes treatment

MicroRNAs in maternal blood may predict development of preeclampsia

Fewer traffic collisions during shutdown means longer waits for organ donations

Researchers are developing a diagnostic test that predicts the advanced stages of COVID-19 patients

Novel insights on SARS-CoV-2 cell entry may inform further vaccine and treatment development

New and unexplored angle in the binding of SARS-CoV-2 to host cells

Sociodemographic factors linked to positive SARS-CoV-2 test result in primary care

High DPP3 concentration in the blood predicts multiple organ failure in burn patients

Novel study tracks symptomatic and asymptomatic COVID-19 spread in pediatric dialysis unit

ACTG initiates clinical trial to evaluate treatment for COVID-19

Anti-inflammatory drug may improve respiratory function in some severe COVID-19 cases

Does HIV infection increase the severity of COVID-19?

Researchers urge Ireland government to change recommendations for vitamin D supplements

Study shows why older individuals are vulnerable to COVID-19

Analysis of single-cell data indicates that SARS-Cov-2 targets many cell types

Experimental two-in-one diabetes shot provides better blood sugar control

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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