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Ulcerative colitis and a missing microbe in the gut

Ulcerative colitis is a seriously debilitating inflammatory disease of the bowel leading to crippling symptoms that can affect the quality of life severely. Researchers from Stanford University School of Medicine have found in a new study that a missing microbe could be linked to this condition. The study was published today in the latest issue of the journal Cell Host & Microbe.

25 Feb 2020

Researchers study why colon cancer is more lethal in pediatric and young adult patients

Colon cancer is more likely to be lethal in children and young adults than middle-aged adults. In a single-institution study, researchers at The University of Texas MD Anderson Cancer Center, Houston, Tex., found that differences in mortality rates persist regardless of whether pediatric, adolescent, and young adult patients (aged 24 and younger) were born with a predisposition for colon abnormalities or disease and for the first time conclude that young people are more likely to have metastases outside the colon, into the abdominal cavity, when they are diagnosed.

23 Feb 2020

UCI makes tremendous strides in prevention, early detection and treatment of cancer

Like most people, John Gifford wasn't looking forward to a colonoscopy when he arrived on the UCI Medical Center campus in Orange in 2018.

23 Feb 2020

New Endothelial Cell Atlas can be used to improve treatments for many diseases

New surprising knowledge on endothelial cells in a dozen different murine tissues is now available in an open access, user-friendly, database for professionals.

20 Feb 2020

Racial disparities found in timing and type of treatment for colorectal cancer patients

In a new study published in Cancer Epidemiology, Associate Professor Dr. Cara Frankenfeld of the George Mason College of Health and Human Services found racial disparities in how the presence of cancer-related diagnostic and treatment technology is related to colorectal cancer patient outcomes in Georgia.

19 Feb 2020

Geriatric-specific characteristics linked to hospital readmission risk of elderly surgical patients

Researchers have examined new geriatric-specific characteristics that appear to raise the risk of elderly surgical patients having an unplanned hospital readmission within a month of initially leaving the hospital.

18 Feb 2020

Mediterranean diet promotes healthy aging with healthier gut microbiome

A new study published online in the journal Gut in February 2020 reports the striking health-promoting effects of switching to a Mediterranean diet for just one year. The results were due to an increase in the health and number of gut bacteria that favor a healthy diet.

17 Feb 2020

Scientists find a way to block the growth of kidney cancer

Scientists at the MDC have discovered stem cells responsible for the most common form of kidney cancer. The team of Walter Birchmeier has found a way to block the growth of these tumors in three models of the disease.

17 Feb 2020

Study provides a detailed molecular snapshot of endometrial cancer

A study published Feb. 13 in Cell provides an unprecedented look at the dozens of molecular steps that occur to bring about endometrial cancer, commonly known as uterine cancer.

14 Feb 2020

Study provides new details about therapy-associated polyposis in childhood cancer survivors

In a paper published online today, Dana-Farber Cancer Institute researchers provide new details about a recently discovered condition in which childhood cancer survivors develop numerous colorectal growths called polyps despite not having a hereditary susceptibility to the condition.

12 Feb 2020

Study finds impact of frailty on long‐term outcomes after emergency surgery

Frailty is the medical term for becoming weaker or experiencing lower levels of activity/energy. Becoming frail as we age increases our risk for poor health, falls, disability, and other serious concerns. This can be especially true for older people facing surgery, up to half of whom are classified as frail.

11 Feb 2020

Smoking cessation goody bag helps people quit smoking

While sitting in the dentist's office, Hollings Cancer Center researcher Matthew Carpenter, Ph.D., of the Medical University of South Carolina, had a bright idea.

9 Feb 2020

Georgia State researcher receives $1.67 million federal grant to study gut immunity

Dr. Tim Denning, professor and associate director of the Institute for Biomedical Sciences at Georgia State University, has received a four-year, $1.67 million federal grant to study how an immunological pathway influences inflammatory signaling in the intestine that can lead to chronic human diseases such as inflammatory bowel disease.

9 Feb 2020

Fly model could help lay the foundation for new therapies to fight 'difficult' pathogen

The Clostridium difficile pathogen takes its name from the French word for "difficult." A bacterium that is known to cause symptoms ranging from diarrhea to life-threatening colon damage, C. difficile is part of a growing epidemic of concern for the elderly and patients on antibiotics.

8 Feb 2020

Cedars-Sinai researchers to study role of fat in promoting cancer spread to liver

A diagnosis of pancreatic or colon cancer often sparks dread about the disease's likely next destination: the liver. That's because liver metastasis is a leading cause of death in these patients.

6 Feb 2020

New robot will assist surgeons during uterine operations

The project has been conducted in collaboration with the Gynaecology and Obstetrics Department, General Surgery, Urology and Thoracic Surgery of Valencia's General Hospital, through their Research Foundation and with the support of the Valencian Innovation Agency of Valencia's regional government, in the framework of a project to boost innovation in robotic surgery.

6 Feb 2020

'Watch-and-Wait' strategy may help rectal cancer patients to safely evade surgery

A team of doctors and scientists from the Champalimaud Clinical Centre in Lisbon, Portugal, and the Netherlands Cancer Institute in Amsterdam, has shown that patients with "low" rectal cancer (that is, very close to the anus) who show no sign of their tumors after a course of radio- and chemotherapy can safely choose to postpone invasive and complication-prone surgical procedures.

6 Feb 2020

Gut bacteria help regulate contraction and relaxation of colon muscles

Micro-organisms in the gut support healthy digestion by helping nerve cells within the intestine to regulate the contraction and relaxation of the muscle wall of the colon, according to new research from the Crick and Bern University.

5 Feb 2020

Novel approach may offer a more effective way to eradicate colorectal cancer cells

A novel approach to reverse the progression of healthy cells to malignant ones may offer a more effective way to eradicate colorectal cancer cells with far fewer side effects, according to a team of researchers based in South Korea.

3 Feb 2020

Annual lung cancer screening with LDCT reduces lung cancer deaths

The Dutch-Belgian Randomized Lung Cancer Screening Trial, known as the NELSON trial (de Koning et. al), published Jan. 29 in the New England Journal of Medicine (NEJM), reconfirms that annual lung cancer screening with low-dose computed tomography (LDCT) in high-risk patients significantly reduces lung cancer deaths.

30 Jan 2020

Colon News and Research

Ulcerative colitis and a missing microbe in the gut

Researchers study why colon cancer is more lethal in pediatric and young adult patients

UCI makes tremendous strides in prevention, early detection and treatment of cancer

New Endothelial Cell Atlas can be used to improve treatments for many diseases

Racial disparities found in timing and type of treatment for colorectal cancer patients

Geriatric-specific characteristics linked to hospital readmission risk of elderly surgical patients

Mediterranean diet promotes healthy aging with healthier gut microbiome

Scientists find a way to block the growth of kidney cancer

Study provides a detailed molecular snapshot of endometrial cancer

Study provides new details about therapy-associated polyposis in childhood cancer survivors

Study finds impact of frailty on long‐term outcomes after emergency surgery

Smoking cessation goody bag helps people quit smoking

Georgia State researcher receives $1.67 million federal grant to study gut immunity

Fly model could help lay the foundation for new therapies to fight 'difficult' pathogen

Cedars-Sinai researchers to study role of fat in promoting cancer spread to liver

New robot will assist surgeons during uterine operations

'Watch-and-Wait' strategy may help rectal cancer patients to safely evade surgery

Gut bacteria help regulate contraction and relaxation of colon muscles

Novel approach may offer a more effective way to eradicate colorectal cancer cells

Annual lung cancer screening with LDCT reduces lung cancer deaths

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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