Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

Doctors must listen when patients talk of a failing memory

A team at the Aging and Memory Research Center, Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, has found that a higher self awareness of memory difficulties may be associated with brain function decline over time, particularly in older adults with a genetic risk for Alzheimer's disease.

6 Apr 2006

Inflammation cuts both ways

Inflammation cuts both ways. When invaded by an infectious agent, for example, the body calls on the forces of inflammation to fight and defeat the intruder.

6 Apr 2006

Higher self awareness of memory difficulties may be associated with brain function decline over time

Published in the April issue of the Archives of General Psychiatry, the study offers a greater understanding of how different types and varying degrees of memory complaints may relate to brain function decline, a finding that may lead to early treatment interventions for people who could develop Alzheimer's disease.

4 Apr 2006

International team tackle protein folding

A team of researchers from EPFL, (Ecole Polytechnique Fidirale de Lausanne), the University of Lausanne, Northwestern University and Tel Aviv Universitybring biology and statistical physics together to answer the question of how molecular chaperones fold, unfold and pull proteins around in the cell.

4 Apr 2006

Regular consumption of either black or green tea may reduce risk of Alzheimer's

Tea may be more than a trendy coffee alternative, according to researchers at the Douglas Hospital Research Centre (DHRC).

4 Apr 2006

Promising new targets for Alzheimer's drug therapies

An enzyme previously associated with preventing the dementia of Alzheimer's disease now appears to play an even bigger role in safeguarding against the disease, bringing the promise of new targets for drug therapies.

4 Apr 2006

Enzymes that harm brain immediately after stroke may be beneficial days later

Insights from the study could change the way stroke is treated, extending the window for effective treatment from a couple of hours to a couple of weeks. The results may suggest new ideas for drug development.

4 Apr 2006

New way of targeting proteins to exosomes - potential for melanoma, Alzheimer's disease

Researchers at the University of Pennsylvania School of Medicine have discovered how a protein called Pmel17 is sorted by pigment cells in the skin and eye to make a fiber matrix that eventually sequesters melanin, the dark pigment found in skin, hair, and eyes.

28 Mar 2006

Researchers find environmentally friendly ways to produce more Taxol

As the effective cancer-treatment drug Taxol enters its next generation, Michigan State University announces discoveries which point to both environmentally friendly ways to produce more Taxol, and ultimately innovations to produce a more potent second-generation drug.

28 Mar 2006

MRI study shows way to prevent development of degenerative brain diseases

A magnetic resonance imaging (MRI) study at UCLA opens new doors to assessing and potentially preventing brain iron accumulation associated with risk of developing degenerative brain diseases such as Alzheimer's, Parkinson's and Dementia With Lewy Bodies.

27 Mar 2006

The choroid plexus prevents build up of plaque related to Alzheimer's disease

Researchers have discovered that an organ in the brain called the choroid plexus apparently plays a critical role in preventing the accumulation of a protein associated with Alzheimer's disease.

23 Mar 2006

Zinc's role in Alzheimer's disease

Zinc may be a familiar dietary supplement to millions of health-conscious people, but it remains a mystery metal to scientists who study zinc's role in Alzheimer's disease, stroke and other health problems.

23 Mar 2006

Study shows that cell transplantation therapy may improve brain receptor function in patients who suffered from cerebral stroke

Japanese researchers have found a piece of the "missing link" about how bone marrow stromal cells restore lost neurologic function when transplanted into animals exhibiting central nervous system disorders, according to a study in the March issue of the Journal of Nuclear Medicine.

21 Mar 2006

Inhibiting gamma secretase may prevent amyloid plaque build-up thought to trigger Alzheimer's disease

Oregon Health & Science University is participating in a national study of a drug that may prevent Alzheimer's disease by blocking an enzyme that produces plaques believed to trigger the disorder.

21 Mar 2006

Donepezil (Aricept) helps cognitive function in brain tumor patients after radiation

A drug that is marketed to treat Alzheimer's disease also improves cognitive function, mood and quality of life in brain tumor patients following radiation therapy, according to a research team at Wake Forest University Baptist Medical Center.

21 Mar 2006