Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

Study provides further insight into the molecular control of apoptosis

Researchers at Yale School of Medicine have gained deeper understanding of two members of a family of proteins called caspases that play a key role in promoting apoptosis, a process in which the cell responds to external signals by essentially committing suicide.

23 Feb 2006

We may learn best on an empty stomach!

Researchers at Yale School of Medicine have found evidence that a hormone produced in the stomach directly stimulates the higher brain functions of spatial learning and memory development.

23 Feb 2006

Education and rates of cognitive decline in incident Alzheimer's disease

High levels of education may help ward off Alzheimer's disease, but they also speed up its progression once developed, reveals research in the Journal of Neurology Neurosurgery and Psychiatry.

21 Feb 2006

Tetrabenazine cuts down involuntary movements in Huntington's disease

The medication tetrabenazine cut down involuntary movement in patients with Huntington's disease on average by about 25 percent, with many patients experiencing a greater improvement, according to a study in the February 14 issue of the journal Neurology.

17 Feb 2006

Major Alzheimer's discovery

A team from the Faculty of Medicine at Universiti Laval and the research centre at CHUQ (Centre hospitalier universitaire de Quibec) has discovered a natural defence mechanism that the body deploys to combat nerve cell degeneration observed in persons with Alzheimer's disease (AD).

17 Feb 2006

Research suggests that a common mechanism may underlie a variety of protein folding diseases

Misfolded and damaged proteins are common to all human neurodegenerative diseases. Clumps of these aggregated proteins destroy neurons within the brain and cause disease.

16 Feb 2006

Researchers develop way to visualize synchronized interactions of nerve cells in the brain

Researchers at the University of Minnesota Medical School and the Brain Sciences Center at the Minneapolis VA Medical Center have discovered a new way to assess how brain networks act together.

16 Feb 2006

Brain scans may detect neurological decline in normal people

Brain scans may detect neurological changes in people who exhibit no outward signs of cognitive decline but who later develop dementia or mental impairment, according to the results of a new study led by researchers at the University of California, Berkeley.

16 Feb 2006

Research may help explain Alzheimer's memory loss

Based on laboratory research, scientists at Georgetown University Medical Center have a new theory as to why people with Alzheimer's disease have trouble performing even the simplest memory tasks, such as remembering a family member's name.

16 Feb 2006

A high level of education means Alzheimer's hits later, but harder and faster

According to researchers at the Columbia University Medical Center in New York, high levels of education may help ward off Alzheimer’s disease, but they also speed up its progression once the disease has developed.

16 Feb 2006

Risk of Alzheimer's 80% genetic

In the largest twin study to date, researchers in the U.S. looked at the Swedish Twin Registry to see which factors lead to Alzheimer's disease (AD).

14 Feb 2006

NogoReceptor reduces Alzheimer's plaque

Increasing the level of a protein that plays a key role in traumatic spinal cord injuries and multiple sclerosis reduces the concentration of disease-causing plaque in Alzheimer's disease, Yale School of Medicine researchers report in the Journal of Neuroscience.

12 Feb 2006

Alzheimer's disease appears to be highly heritable

In a large study of twins, Alzheimer's disease appears to be highly heritable and genetic factors may also influence timing of the disease, according to an article in the February Archives of General Psychiatry.

9 Feb 2006

Depression linked to Alzheimer's

A lifetime history of depression is associated with increased plaques and tangles in the brains of those with Alzheimer's disease and more rapid cognitive decline, according to a study by researchers at the Alzheimer's Disease Research Center at Mount Sinai School of Medicine.

9 Feb 2006

Alzheimer disease has a genetic cause in up to 80 percent of cases

"Our finding confirms the higher estimates that have been suggested previously. The important thing is that no one has had this large a sample before," Gatz said, adding the size was 10 times that of any previous study.

7 Feb 2006

Link between dementia and cancer

By expressing a protein associated with Alzheimer's disease in the brain of the fruit fly, researchers have demonstrated an intriguing link between neuronal death and proteins previously associated with cancer.

7 Feb 2006

Abraham Lincoln may have suffered from movement disorder

Researchers at Johns Hopkins and the University of Minnesota have discovered a gene mutation in the descendants of Abraham Lincoln's grandparents that suggests the Civil War president himself might have also suffered from a disease that destroys nerve cells in the cerebellum-- the part of the brain that controls movement.

7 Feb 2006

Study finds brain changes begin gradually in 'middle age'

A study looking at brain function in young, middle-aged and older adults has identified changes in brain activity that begin gradually in middle age - and which may explain why older adults find it difficult to concentrate in busy environments and filter out irrelevant information.

7 Feb 2006

Memory loss and menopause

Women who feel that they become more forgetful as menopause approaches shouldn't just ignore it, there may be something to their own widespread reports that they're more likely to forget things as menopause approaches

5 Feb 2006

HMRI researcher lights a path to understanding brain diseases

Neurologist Mike Harrington of Pasadena, California's Huntington Medical Research Institutes argues that soon we may be able to detect brain disease before symptoms even begin. The secret is in the cerebrospinal fluid, the clear liquid that cushions our brain and spinal cord.

2 Feb 2006