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SARS-CoV-2 infection shown to reduce the expression of vitamin D pathway components

A recent computational study from India implicated a dysregulated vitamin D pathway in the pathobiology of the infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – and opened the door for experimental validation of these observations.

23 Dec 2020

Frequent and rapid testing may reduce SARS-CoV-2 transmission in carehomes

A team of scientists from the Centers for Disease Control and Prevention, United States, recently conducted a study to evaluate the effectiveness of serial testing and isolation of healthcare personnel in nursing homes in preventing the transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative pathogen of coronavirus disease 2019 (COVID-19).

23 Dec 2020

Public adherence to COVID-19 guidelines in Norway: a case study

To evaluate and understand the adherence to public health actions recommended by the government, a team in Norway undertook a study funded in part by the Norwegian Research Council’s Centres of Excellence Funding Scheme and by the project: A realtime analytical pipeline for preparedness, planning, and response during the COVID-19 pandemic in Norway.

23 Dec 2020

At risk of extinction, black-footed ferrets get experimental COVID vaccine

In late summer, as researchers accelerated the first clinical trials of COVID-19 vaccines for humans, a group of scientists in Colorado worked to inoculate a far more fragile species.

23 Dec 2020

SARS-CoV-2 mutations may evade T cell immunity

A potentially disturbing new study suggests that SARS-CoV-2 may be undergoing strategic mutations that affect the host immune capacity to recognize and combat the pathogen via T effector cells.

23 Dec 2020

COVID-19 severity could be linked to genetic variance

A new study describes some potentially important genetic factors in the host that may shape the clinical symptoms and signs of the disease.

23 Dec 2020

Cell-mediated immunity may be more important than neutralizing antibodies in COVID-19 outcome

A new study sheds light on some important differences between asymptomatic and symptomatic patients with coronavirus disease 2019 (COVID-19).

23 Dec 2020

Researchers use fruit fly model to understand COVID-19-related neurological complications

Researchers claim to have reproduced disease mechanisms due to coronavirus disease 2019 (COVID-19) in the fruit fly, Drosophila, while also providing proof of the efficacy of one drug against these disease processes. If validated, these findings represent a new understanding of how the virus causes neurological symptoms that could help develop more effective therapies.

23 Dec 2020

Phase 2/3 COVID-19 study evaluates safety, potential identification of preliminary efficacy signals

Top-line data from the 270-patient global Phase 2/3 COVID-19 study expected Q1/2021. Top-line data from the 40-patient U.S. Phase 2 study of opaganib in severe COVID-19 expected in the coming days; this non-powered study was designed to evaluate safety and potential identification of preliminary efficacy signals in support of the global Phase 2/3 study of opaganib.

23 Dec 2020

Early clinical data demonstrates the efficacy of existing drug in treating COVID-19

In what has the potential to significantly change how Corona patients are being treated and the severity of the disease, research spearheaded at Jerusalem's Hebrew University gathered early clinical evidence demonstrating the efficacy of an existing drug in treating COVID-19.

22 Dec 2020

Researchers evaluate self-administered 'scratch-and-sniff' tests for COVID-19

A self-administered 'scratch-and-sniff' test for COVID-19 may be around the corner, according to researchers at Penn State, the University of Florida and Arizona State University.

22 Dec 2020

Study finds significantly lower mother-to-newborn transfer of anti-SARS-CoV-2 antibodies

Pregnant women may be especially vulnerable to developing more severe cases of COVID-19 following SARS-CoV-2 infection, but little is known about their anti-SARS-CoV-2 immune response or how it may affect their offspring.

22 Dec 2020

The power of public health screening in mitigating the spread of COVID-19

Testing for COVID-19 has been central in the fight against SARS-CoV-2/ COVID-19. While most efforts, including regulations, have focused on testing as a clinical medical diagnostic tool, the most powerful forms of testing to help control the pandemic have rarely been used or recognized, according to Michael Mina, MD, PhD.

22 Dec 2020

Study finds a distinct shift in method of nurse suicides

In a new study, University of California San Diego School of Medicine and UC San Diego Health researchers report that the rate of firearm use by female nurses who die by suicide increased between 2014 to 2017.

22 Dec 2020

COVID-19 patients retain immunity against the virus for at least 8 months

Australian researchers have revealed - for the first time - that people who have been infected with the COVID-19 virus have immune memory to protect against reinfection for at least eight months.

22 Dec 2020

SARS-CoV-2 antibody levels and types differ by disease severity, study finds

Researchers have measured the antibody levels and types in hospitalized coronavirus disease 2019 (COVID-19) patients with different disease severity. Their results suggest gut immune pathways could play a role in reducing virus-based inflammation and recovery.

22 Dec 2020

Scientists isolate anti-COVID-19 nanobodies produced by a llama

National Institutes of Health researchers have isolated a set of promising, tiny antibodies, or "nanobodies," against SARS-CoV-2 that were produced by a llama named Cormac.

22 Dec 2020

What are the potential benefits of SARS-CoV-2 antigen-based rapid diagnostic tests?

A team of researchers from the Johns Hopkins University, USA; Imperial College London, UK; and Foundation for Innovative New Diagnostics, Switzerland, recently compared the effectiveness of Ag-RDT, NAAT, and clinical judgment alone in the diagnosis of COVID-19 in symptomatic patients.

22 Dec 2020

Large-scale study set up in UK to assess possibility of SARS-CoV-2 re-infection among healthcare workers

Researchers from Public Health England are conducting a large-scale prospective longitudinal study to determine whether healthcare workers who have previously developed coronavirus disease 2019 (COVID-19) are immune to reinfection with the causative agent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

22 Dec 2020

Pregnant women in third trimester unlikely to pass SARS-CoV-2 infection to newborns

A new study demonstrates that women in their third trimester are unlikely to pass a SARS-CoV-2 infection onto their babies.

22 Dec 2020

SARS News and Research

SARS-CoV-2 infection shown to reduce the expression of vitamin D pathway components

Frequent and rapid testing may reduce SARS-CoV-2 transmission in carehomes

Public adherence to COVID-19 guidelines in Norway: a case study

At risk of extinction, black-footed ferrets get experimental COVID vaccine

SARS-CoV-2 mutations may evade T cell immunity

COVID-19 severity could be linked to genetic variance

Cell-mediated immunity may be more important than neutralizing antibodies in COVID-19 outcome

Researchers use fruit fly model to understand COVID-19-related neurological complications

Phase 2/3 COVID-19 study evaluates safety, potential identification of preliminary efficacy signals

Early clinical data demonstrates the efficacy of existing drug in treating COVID-19

Researchers evaluate self-administered 'scratch-and-sniff' tests for COVID-19

Study finds significantly lower mother-to-newborn transfer of anti-SARS-CoV-2 antibodies

The power of public health screening in mitigating the spread of COVID-19

Study finds a distinct shift in method of nurse suicides

COVID-19 patients retain immunity against the virus for at least 8 months

SARS-CoV-2 antibody levels and types differ by disease severity, study finds

Scientists isolate anti-COVID-19 nanobodies produced by a llama

What are the potential benefits of SARS-CoV-2 antigen-based rapid diagnostic tests?

Large-scale study set up in UK to assess possibility of SARS-CoV-2 re-infection among healthcare workers

Pregnant women in third trimester unlikely to pass SARS-CoV-2 infection to newborns

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