Alzheimer's Disease News and Research

RSS

Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

Alzheimer disease and the blood brain barrier

Increased production of the amyloid-beta (Abeta) peptide can lead to Abeta aggregation and buildup in the brain and rare familial forms of early onset Alzheimer disease (AD).

20 Oct 2005

Award for genetic study that revolutionised thinking on epilepsy

Melbourne researcher, Professor Sam Berkovic, has been awarded the prestigious Zulch Prize from the Max Planck Society in Germany in recognition of his groundbreaking investigations into the genetic foundations of epilepsy.

19 Oct 2005

South Korea opens controversial international stem cell bank

South Korea has opened a bank in Seoul that will create and supply new lines of embryonic stem cells for research around the world.

19 Oct 2005

Study of the effects of aripiprazole, olanzapine, quetiapine and risperidone, in elderly patients with dementia

Some newer antipsychotic medications may be associated with a small increased risk of death when used to treat elderly dementia patients, psychiatrists at Johns Hopkins warn.

18 Oct 2005

Aβ and Fyn cooperate to cause Alzheimer-like changes in the brain

Reporting in two companion papers in the October 19 issue of the Journal of Neuroscience, investigators from the Gladstone Institute of Neurological Disease show in genetically engineered mouse models of the disease that the accumulation of Alzheimer-related neurotoxic amyloid-beta (Aâ) peptides can deplete key proteins in a specific memory center of the brain.

18 Oct 2005

Cannabis smoke less likely to cause cancer than tobacco smoke

According to a leading U.S. expert, cannabis smoke is less likely to cause cancer than tobacco smoke.

18 Oct 2005

Discovery could lead to tests for the clinic or battlefield to diagnose ailments with just a few drops of blood

A way to detect fragments of broken brain cells that leak into the bloodstream may help doctors more quickly and precisely treat people with severe head injuries or brain diseases, say researchers at the University of Florida's McKnight Brain Institute.

17 Oct 2005

Researchers shed light on a key molecular switch in T helper cells

Defects in immune system cells called T helper cells may lead to diseases characterized by a faulty inflammatory response such as autoimmunity and asthma. Understanding the molecular steps involved in how T helper cells mature may help researchers develop treatments for these diseases.

17 Oct 2005

High fat, low carb diet may help Alzheimer's sufferers

Scientists have discovered that a high fat, low carbohydrate diet improves Alzheimer's disease in mice and say the study results may also have implications for dieters.

17 Oct 2005

High fat, low carb diet improves Alzheimer's disease in mice

A report published today in the BioMed Central, open access journal Nutrition and Metabolism, showed that a brain protein, amyloid-beta, which is an indicator of Alzheimer's disease, is reduced in mice on the so-called ketogenic diet.

16 Oct 2005

Ebixa (memantine) approved for the treatment of moderate Alzheimer's disease

The Committee for Medicinal Products for Human Use (CHMP) has announced its decision to extend Ebixa’s current indication (moderately severe to severe disease) to include moderate stages of Alzheimer’s disease (AD).

16 Oct 2005

Biologists uncover pivotal role of a gene called "Cut"

A DNA-binding protein, Cut interprets and transcribes the developmental signals sent through the "Notch" gene, which regulates a layer of epithelial cells as they replicate and divide. But when Cut garbles those signals the result is uncontrolled cell proliferation, sometimes with dire genetic and health consequences.

12 Oct 2005

Combining fMRI and PET scanning creates a way to compare different measurements of the brain's function concurrently

Clinical researchers from the University of Pennsylvania Health System (UPHS) are the first to combine fMRI and PET scanning in radiology, creating a way to compare different measurements of the brain's function concurrently. This analysis could lead to better diagnosis and treatment in patients suffering from brain disorders, like Alzheimer's disease.

12 Oct 2005

Aging may intensify and prolong feeling run down when common infections like the flu occur

A new study, done with mice and published in the Federation of the American Societies of Experimental Biology Journal, suggests that miscommunication between the immune system and brain may be to blame for extended sickness symptoms and other cognitive disorders in elderly people and animals with an infection.

11 Oct 2005

Natural cancer killing cells from the human embryonic stem cells

For the first time, stem cell researchers at the University of Minnesota have coaxed human embryonic stem cells to create cancer-killing cells in the laboratory, paving the way for future treatments for various types of cancers (or tumors).

11 Oct 2005

Obesity linked to dementia and Alzheimer's disease

Individuals who were obese at midlife had an increased risk for dementia later in life compared to individuals of normal weight, according to an article in the October issue of Archives of Neurology.

10 Oct 2005

New way to measure the impact of AIDS on the living brain

A new University of California - Los Angeles/University of Pittsburgh imaging study for the first time shows the selective pattern of destruction inflicted by AIDS on brain regions that control motor, language and sensory functions. High-resolution 3-D color scans created from magnetic resonance images (MRI) vividly illustrate the damage.

10 Oct 2005

Fear of falling gait

The patient came into the doctor's office in a wheelchair, weighted down by a diagnosis of Parkinson's disease, taking medication for the disorder and insisting she was unable to stand or walk. Thirty minutes later, after jogging down the hallway, she strolled out the door.

9 Oct 2005

Specific gene on chromosome 15 regulates inflammation

A team of international researchers has discovered that a specific gene on chromosome 15 regulates inflammation, a finding with implications for a wide range of disorders, including cancer, cardiovascular disease, diabetes, obesity, Alzheimer's, and infections. The findings are published in the October 9 online issue of Nature Genetics.

9 Oct 2005

Osmolyte findings could have implications for the study of Alzheimer's disease, cystic fibrosis, kidney disease

Researchers at the University of Texas Medical Branch at Galveston (UTMB) have developed a new way to predict the ability of certain small molecules to protect proteins in the cells of a wide variety of organisms living in extreme environments.

9 Oct 2005