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Study provides better understanding of how therapeutic resistance develops in lung cancer

New Cleveland Clinic research has uncovered key information about cellular interaction between tumor cells and normal tissue, providing better understanding of how therapeutic resistance develops.

1 Jul 2022

New antibody-based method for SARS-CoV-2 detection does not require a blood sample

Despite significant and stunning advances in vaccine technology, the COVID-19 global pandemic is not over. A key challenge in limiting the spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is identifying infected individuals.

1 Jul 2022

Scientists develop antibody test to keep track of immunity to SARS-CoV-2 variants

The experts agree -; the pandemic is not over. Infections are ticking up again, fueled by the new variants our immune systems are ill prepared for.

1 Jul 2022

The antiviral effects of thiol drugs in COVID-19

A recent study investigated the effects of thiol drugs on SARS-CoV-2.

1 Jul 2022

The identification and characterization of a thermophilic Cas13a ortholog highly active at the temperatures required for RT-LAMP

Researchers developed a new detection assay for SARS-CoV-2.

1 Jul 2022

SARS-CoV-2 can evade Paxlovid by multiple mechanisms

In a recent article posted to the bioRxiv* preprint server, researchers at Rutgers, the State University of New Jersey, the University of South Florida, and the Catholic University of America demonstrated that the natural severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) main protease (Mpro) mutations result in nirmatrelvir resistance.

30 Jun 2022

The severity of Omicron BA.4/BA.5 lineages in the South Africa population

Researchers assessed the clinical severity of SARS-CoV-2 Omicron variants.

30 Jun 2022

A fast, highly sensitive, point-of-care RT-LAMP and CRISPR/Cas12a assay for the detection of SARS-CoV-2

Researchers used isothermal amplification with CRISPR-Cas12a to detect SARS-CoV-2.

30 Jun 2022

Study compares protection induced by Delta breakthrough infections vs. COVID boosters against Omicron

Researchers compare the neutralizing ability of antibodies induced by Delta breakthrough infections and a third COVID-19 vaccine against Omicron.

28 Jun 2022

Acute COVID-19 and vaccination induce cross-reactive antibody responses in breast milk

IgA and IgG in human breast milk and blood were assessed for their activity against SARS-CoV-2 and SARS-CoV-1, as well as four other prevalent HCoVs.

28 Jun 2022

Potent antibody with a novel neutralization mechanism against SARS-CoV-2 variants

In a recent study posted to the bioRxiv* pre-print server, researchers in the United States described a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-neutralizing monoclonal antibody (mAb) SP1-77 that broadly neutralized its multiple variants of concern (VOCs).

28 Jun 2022

Acute illness increases cortisol levels in children and adolescents

A new study reports that in children and adolescents without glucocorticoid deficiency, circulating cortisol levels were higher during acute illnesses.

28 Jun 2022

The potential of DNA-based SARS-CoV-2 vaccine candidates

Researchers evaluated the immunogenicity of DNA-based candidate vaccines against SARS-CoV-2 in mice.

28 Jun 2022

Cell-based assay highlights differences in antibody neutralizing capacity for SARS-CoV-2 variants

A recent study by scientists at Celentyx Ltd, the University of Birmingham, and the University of Warwick and posted to the bioRxiv* preprint server illustrated a cell-based severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) protein attachment assay.

28 Jun 2022

Researchers analyze potential of niclosamide as a SARS-CoV-2 treatment

A recent study posted to the bioRxiv* preprint server assessed whether niclosamide could be employed in coronavirus disease 2019 (COVID-19) therapy.

28 Jun 2022

Recombinant SARS-CoV-2 harboring double reporters for COVID-19 surveillance

In a recent article posted to the bioRxiv* preprint server, researchers at Texas Biomedical Research Institute, Georgia State University, and the University of Alabama at Birmingham developed a bireporter-expressing recombinant severe acute respiratory syndrome coronavirus 2 (rSARS-CoV-2) for tracking SARS-CoV-2 infection.

27 Jun 2022

Assay News and Research

Study provides better understanding of how therapeutic resistance develops in lung cancer

New antibody-based method for SARS-CoV-2 detection does not require a blood sample

Scientists develop antibody test to keep track of immunity to SARS-CoV-2 variants

The antiviral effects of thiol drugs in COVID-19

The identification and characterization of a thermophilic Cas13a ortholog highly active at the temperatures required for RT-LAMP

SARS-CoV-2 can evade Paxlovid by multiple mechanisms

The severity of Omicron BA.4/BA.5 lineages in the South Africa population

A fast, highly sensitive, point-of-care RT-LAMP and CRISPR/Cas12a assay for the detection of SARS-CoV-2

Study compares protection induced by Delta breakthrough infections vs. COVID boosters against Omicron

Acute COVID-19 and vaccination induce cross-reactive antibody responses in breast milk

Potent antibody with a novel neutralization mechanism against SARS-CoV-2 variants

Acute illness increases cortisol levels in children and adolescents

The potential of DNA-based SARS-CoV-2 vaccine candidates

Cell-based assay highlights differences in antibody neutralizing capacity for SARS-CoV-2 variants

Researchers analyze potential of niclosamide as a SARS-CoV-2 treatment

Recombinant SARS-CoV-2 harboring double reporters for COVID-19 surveillance

3rd COVID vaccine significantly reduced hospitalizations and deaths during Australia's 1st Omicron wave

Investigating PREVENT-19 trial findings of serological correlates of immune protection and risk against COVID-19

Antigenic differences between early SARS-CoV-2 variants

Persistent fatigue post-COVID-19 in pregnant women

eBook: Using iPSCs models for human disease research and drug discovery eBook

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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