Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

New clue to the causes of neurodegenerative diseases

Scientists funded by the Medical Research Council (MRC), the Wellcome Trust, BBSRC - the Biotechnology and Biological Sciences Research Council and the EU have made an important discovery about the mechanisms underlying degenerative brain diseases.

26 Jun 2005

Folic acid improves memory and protects the brain from aging

According to scientists in Holland high doses of folic acid might help slow the cognitive decline of aging.

22 Jun 2005

Researchers discover mechanism that causes a protein to clump together in brain cells of people with Parkinson's disease

The protein clumping is part of a "vicious cycle," the researchers said. As the proteins cluster, they inhibit an enzyme that normally breaks them down, leading to the formation of even more masses.

21 Jun 2005

Worldwide cost of Alzheimer's disease and dementia estimated at $156 billion

The first estimate of the worldwide direct costs of Alzheimer’s disease and dementia care was released at the Alzheimer’s Association International Conference on the Prevention of Dementia. As a result, scientists, advocates and those affected by the disease are calling for increased funding for research and support services.

21 Jun 2005

No increase in anxiety or depression when children of people with Alzheimer's get genetic testing

Adult children of people with Alzheimer’s disease were satisfied and unharmed by the experience of genetic risk assessment, even when results suggested they might be at risk, according to a new study presented at the first Alzheimer’s Association’s International Conference on the Prevention of Dementia.

21 Jun 2005

Researchers isolate substance most responsible for the tissue damage that follows initial spinal cord injury

Purdue University researchers may have isolated the substance most responsible for the tissue damage that follows initial spinal cord injury, a discovery that could also improve treatments for a host of other neurodegenerative conditions.

21 Jun 2005

Computer program that enhances the diagnostic accuracy of positron emission tomography (PET)

German scientists developed a computer program that enhances the diagnostic accuracy of positron emission tomography (PET) scans with Alzheimer's patients, opening the door for earlier treatment of this progressive brain disorder. Details of their findings were provided at the Society of Nuclear Medicine's 52nd Annual Meeting in Toronto.

20 Jun 2005

Enzyme family plays role in Alzheimer's

The route to a treatment for Alzheimer's disease may have become more straightforward with the discovery that a key enzyme known to have a major role in this disease is in fact part of a family of enzymes. Only some family members play a role in the progression of this brain-wasting illness, new research at the University of Toronto has found.

20 Jun 2005

Fruit juice, regular exercise, clean teeth and a drink in moderation, all help prevent Alzheimer's

According to a new report, drinking fruit juice, getting regular exercise and brushing your teeth could all help prevent Alzheimer's.

20 Jun 2005

Studies show Alzheimer's prevented by drinking juice daily and having the occasional alcoholic drink

At a conference in the U.S. on Alzheimer's disease on June 19, researchers said that they think brain scans and simple blood tests may offer the best ways to predict who has the highest risk of Alzheimer's disease.

20 Jun 2005

First demonstration that reduced metabolic activity in the hippocampus may be used to help predict future Alzheimer's disease

New York University School of Medicine researchers have developed a brain scan-based computer program that quickly and accurately measures metabolic activity in a key region of the brain affected in the early stages of Alzheimer's disease.

19 Jun 2005

Arterial spin labeling distinguishes between Alzheimer's disease and frontotemporal dementia

A non-invasive magnetic resonance imaging (MRI) technique called arterial spin labeling is just as accurate as invasive scanning techniques in distinguishing Alzheimer's disease from frontotemporal dementia (FTD) in the brains of elderly people, according to a new study at the San Francisco VA Medical Center (SFVAMC).

19 Jun 2005

Early exposure to inflammatory disease multiplies Alzheimer's risk

A new study of dementia in identical twins suggests that exposure to inflammation early in life quadruples one's risk of developing Alzheimer's disease.

19 Jun 2005

Pioneering new technology helps ease dementia

In a remarkable enterprise psychologists at St Andrews University, computer experts at Dundee University, and researchers at the Duncan of Jordanstone College of Art in Dundee, have collaborated to produce a "memory jukebox".

16 Jun 2005

First demonstration of a vaccine for Parkinson's

Researchers at the University of California, San Diego (UCSD) School of Medicine working with scientists at Elan Pharmaceuticals, have reported promising results in mice of a vaccine approach to treating Parkinson’s and similar diseases. These results appear in the June edition of the journal Neuron.

15 Jun 2005

Two common gene variations are associated with the risk for developing chronic kidney disease

Two common gene variations are associated with the risk for developing chronic kidney disease, according to a study by researchers at the Johns Hopkins Bloomberg School of Public Health and other institutions. One variant increases risk and the other decreases risk with a similar effect in whites, African-Americans, diabetic and non-diabetic individuals.

14 Jun 2005

Researchers explain how ubiquitin function is determined

University of Maryland researchers have explained, for the first time, why the linkage between the cell-regulating protein molecules called ubiquitins determines their function.

10 Jun 2005

Findings could lead to a new approach in diagnosing and treating Alzheimer’s disease

The human body has its own defense against brain aging: the innate immune system, which helps to clean the brain of amyloid-beta waste products. However, UCLA researchers discovered that some patients with Alzheimer’s disease have an immune defect making it difficult to clean away these wastes.

From MP Biomedicals, LLC 10 Jun 2005

Experimental drug works best in combination with older remedy for Alzheimer's disease and other dementias

An experimental drug combined with an already-popular memory-enhancing compound may further delay memory loss in patients with Alzheimer's disease and other dementias, Johns Hopkins University scientists, in collaboration with researchers from University of North Carolina, have found.

9 Jun 2005

Research opens up new directions for studying prion diseases in humans

The mysterious, highly infectious prions, which cause the severe destruction of the brain that characterizes "mad cow disease" and several human brain degenerative disorders, can be rendered harmless in the laboratory by a slight alternation of the three-dimensional conformation or shape of the prion protein's structure.

9 Jun 2005

Alzheimer's Disease News and Research

Further Reading

New clue to the causes of neurodegenerative diseases

Folic acid improves memory and protects the brain from aging

Researchers discover mechanism that causes a protein to clump together in brain cells of people with Parkinson's disease

Worldwide cost of Alzheimer's disease and dementia estimated at $156 billion

No increase in anxiety or depression when children of people with Alzheimer's get genetic testing

Researchers isolate substance most responsible for the tissue damage that follows initial spinal cord injury

Computer program that enhances the diagnostic accuracy of positron emission tomography (PET)

Enzyme family plays role in Alzheimer's

Fruit juice, regular exercise, clean teeth and a drink in moderation, all help prevent Alzheimer's

Studies show Alzheimer's prevented by drinking juice daily and having the occasional alcoholic drink

First demonstration that reduced metabolic activity in the hippocampus may be used to help predict future Alzheimer's disease

Arterial spin labeling distinguishes between Alzheimer's disease and frontotemporal dementia

Early exposure to inflammatory disease multiplies Alzheimer's risk

Pioneering new technology helps ease dementia

First demonstration of a vaccine for Parkinson's

Two common gene variations are associated with the risk for developing chronic kidney disease

Researchers explain how ubiquitin function is determined

Findings could lead to a new approach in diagnosing and treating Alzheimer’s disease

Experimental drug works best in combination with older remedy for Alzheimer's disease and other dementias

Research opens up new directions for studying prion diseases in humans

eBook: Advancing neurodegenerative research with iPSC-derived microglia models eBook

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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