Drug Discovery News and Research

RSS

The drug discovery process begins with recognizing a disease or clinical condition in which there is a lack of adequate medical treatment. Once a potential drug has been identified, pre-clinical research can begin. This process includes several stages; the first of which involves identifying and validating the prospective drug’s target through assay development, high throughput screening, hit identification and finally, lead optimization. Once the pre-clinical process is complete, the newly synthesized drug candidate is selected for future clinical development.

Deep Longevity collaborates with Longenesis on federated learning and consent management

Regent Pacific Group Limited ("Regent Pacific" or the "Company" and together with its subsidiaries, the "Group"; SEHK:0575.HK) today announced that Deep Longevity, Inc, a company recently acquired by the Group which mainly engaged in the development of explainable artificial intelligence systems to track the rate of aging at the molecular, cellular, tissue, organ, system, physiological, and psychological levels, has entered into a partnership with Longenesis, a leader in consent-enabled safe data curation for research.

23 Oct 2020

Dexamethasone drug may not benefit COVID-19 patients with diabetes or low albumin levels

A new discovery about how the body transports dexamethasone, a drug that can increase the survival chances of patients with severe COVID-19, suggests diabetes and other factors may reduce its potentially lifesaving effectiveness.

23 Oct 2020

New technique uses light to modify disease signaling

Most diseases are caused by aberrant cell signaling processes and basic research in cell signaling is needed to identify targets for future therapeutic approaches, especially in cases where no cures or effective treatments are currently available.

22 Oct 2020

Monoclonal Antibodies: Discovery, Characterization and Challenges

In this interview, News-Medical talks to David Apiyo, a senior manager of applications at Sartorius AG, about monoclonal antibody development and characterization.

22 Oct 2020

Researchers identify new mechanism that modulates cell division

Collaborative work of research groups at the University of Würzburg and the TU Dresden has provided important new insights for cancer research.

22 Oct 2020

Scientists discover key enzyme involved in the development of autoimmune diseases

Scientists affiliated with the Center for Research on Inflammatory Diseases (CRID http://crid.fmrp.usp.br), hosted by the University of São Paulo (USP) in Brazil, have discovered that an enzyme involved in key metabolic processes also plays a role in immune cell differentiation and hence in the development of autoimmune diseases.

19 Oct 2020

NAM announces winners of the inaugural round of Healthy Longevity Catalyst Awards

The National Academy of Medicine, together with seven global collaborators representing nearly 50 countries and territories, today announced the winners of the inaugural round of Healthy Longevity Catalyst Awards.

16 Oct 2020

Ziath to participate in two key virtual biobanking symposia

Ziath announce their participation in two key virtual symposia for scientists involved in biobanking - the ISBER Virtual Symposium 2020 and the Europe Biobank Week 2020.

From Ziath Ltd 16 Oct 2020

Start-up receives NIH grant to accelerate development of contrast agent to detect liver fibrosis

Inlighta Biosciences, LLC, a start-up company led by Jenny Yang, Regents' Professor of Chemistry at Georgia State University, has been awarded a National Institute of Health grant to accelerate development of a magnetic resonance imaging contrast agent to detect liver fibrosis, formation of scar tissue in the liver caused by alcoholic and non-alcoholic fatty liver disease.

15 Oct 2020

Dotmatics introduces a self-service, scientific visualization and analytics application for small molecule discovery

Dotmatics Ltd, a scientific informatics software and services company that is driving the automation of laboratory data workflows for scientific discovery and innovation research, today announced it has expanded its product portfolio to include Blueprint, a self-service, scientific visualization and analytics application for small molecule discovery.

From Dotmatics 15 Oct 2020

Ziath Announces Participation in Key Virtual Symposia

Ziath Announces Their Participation in Key Virtual Symposia

From Ziath Ltd 15 Oct 2020

New machine learning concepts can help develop novel drugs

Tandem mass spectrometry is a powerful analytical tool used to characterize complex mixtures in drug discovery and other fields.

14 Oct 2020

Axol Bioscience introduces multi-electrode array screening services for human iPSC-derived cells

Axol Bioscience today announced the expansion of its services, with the introduction of array screening for human induced pluripotent stem cells.

From Axol Bioscience Ltd 13 Oct 2020

In vitro BA-LRA can help detect small molecule drugs for drug-induced liver injury

BioIVT, a leading provider of research models and services for drug and diagnostic development, today announced the publication of research describing the use of HEPATOPAC® cultures with a targeted in vitro assay to identify small molecule drugs with high potential for drug-induced liver injury (DILI).

13 Oct 2020

Exciting findings on CD8 T cell response in recovered COVID patients

An international team of scientists has identified novel T cell-recognized epitopes spanning different proteins of severe acute respiratory syndrome coronavirus 2 in COVID-19 recovered patients. The scientists have also revealed phenotypical characteristics of the T cell population.

11 Oct 2020

Technological breakthrough may increase COVID-19 testing, reduce wait time and costs

The U.S. Food and Drug Administration has granted emergency use authorization for scientists at UCLA Health to begin using a new method of COVID-19 detection using sequencing technology called SwabSeq.

8 Oct 2020

Researchers use silk nanofibers to enhance 3D cell printing

How do you test, in early-stage research, whether a potential pharmaceutical effectively targets a human tumor, organ, or some other part of the body? How do you grow a new hand or some other body part?

8 Oct 2020

Comet supercomputer performs complex calculations on receptor sequence data from human T cells

While researchers around the world race to develop an effective and safe COVID-19 vaccine, a team from the San Diego Supercomputer Center (SDSC) at UC San Diego contributed to a study led by Vanderbilt Vaccine Center of Vanderbilt University Medical Center (VUMC) on T cell receptors, which play a vital role in alerting the adaptive immune system to mount an attack on invading foreign pathogens including the Coronavirus SARS-CoV-2.

8 Oct 2020

UC Davis School of Medicine and UTHealth receive NIH grant for dementia research

A team of brain scientists from UC Davis School of Medicine and The University of Texas Health Science Center at Houston has been awarded a six-year grant expected to total $53.6 million from the National Institutes of Health.

7 Oct 2020

Production of six monoclonal antibodies against SARS-CoV-2 spike protein

Youjia Guo et al. in a recent bioRxiv preprint paper demonstrate the robust performance of mouse anti-SARS-CoV-2 spike monoclonal antibodies in immunoassays, including western blotting, ELISA, immunofluorescence, and immunoprecipitation and also neutralizing activity in vitro against SARS-CoV-2 infection.

5 Oct 2020

Drug Discovery News and Research

Further Reading

Deep Longevity collaborates with Longenesis on federated learning and consent management

Dexamethasone drug may not benefit COVID-19 patients with diabetes or low albumin levels

New technique uses light to modify disease signaling

Monoclonal Antibodies: Discovery, Characterization and Challenges

Researchers identify new mechanism that modulates cell division

Scientists discover key enzyme involved in the development of autoimmune diseases

NAM announces winners of the inaugural round of Healthy Longevity Catalyst Awards

Ziath to participate in two key virtual biobanking symposia

Start-up receives NIH grant to accelerate development of contrast agent to detect liver fibrosis

Dotmatics introduces a self-service, scientific visualization and analytics application for small molecule discovery

Ziath Announces Participation in Key Virtual Symposia

New machine learning concepts can help develop novel drugs

Axol Bioscience introduces multi-electrode array screening services for human iPSC-derived cells

In vitro BA-LRA can help detect small molecule drugs for drug-induced liver injury

Exciting findings on CD8 T cell response in recovered COVID patients

Technological breakthrough may increase COVID-19 testing, reduce wait time and costs

Researchers use silk nanofibers to enhance 3D cell printing

Comet supercomputer performs complex calculations on receptor sequence data from human T cells

UC Davis School of Medicine and UTHealth receive NIH grant for dementia research

Production of six monoclonal antibodies against SARS-CoV-2 spike protein

ELRIG Drug Discovery: Poster Sessions eBook

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

Latest Life Science News