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New imaging method using fluorescent nanotubes can peer clearly into living mouse's innards

Developing drugs to combat or cure human disease often involves a phase of testing with mice, so being able to peer clearly into a living mouse's innards has real value.

30 May 2011

New positive Cimzia phase IIIb study data on rheumatoid arthritis presented at EULAR meeting

UCB today announced data which showed that the addition of Cimzia to current therapy was associated with a rapid and consistent clinical response in a diverse group of rheumatoid arthritis (RA) patients.

30 May 2011

Cholesterol drug Niaspan fails to protect heart: Study

According to researchers at the National Heart, Lung, and Blood Institute (NHLBI), increasing the dose of niacin to patients with heart disease who are already taking a cholesterol-lowering statin does nothing extra to prevent heart attacks and strokes. Approximately one out of seven Americans have high blood cholesterol, a main risk factor in heart disease, which kills some 800,000 people in the United States annually.

29 May 2011

High blood pressure becoming more common in young adults: Study

According to a new study about one in five young adults may have high blood pressure. The researchers from the University of North Carolina at Chapel Hill analyzed blood pressure data from the National Longitudinal Study of Adolescent Health, called Add Health, and compared it with data from the National Health and Nutrition Examination Survey, commonly referred to as NHANES. They focused specifically on the information about adults age 24 to 32.

29 May 2011

Efficacy of Abbott cholesterol drug in question

A latest study has found that using medication to raise good cholesterol while lowering the bad does NOT translate into fewer adverse cardiovascular events like heart attacks and strokes. The study was revealed Thursday by the National Institutes of Health and it found that high dosages of Abbott Laboratories' Niaspan failed to prevent heart attacks and boosted the likelihood of a stroke when combined with the popular generic cholesterol pill Simvastatin, also known under the brand name Zocor.

29 May 2011

Bacteria that infect cystic fibrosis patients could help combat MRSA

A bacteria which infects people with cystic fibrosis could help combat other antibiotic-resistant microbes, according to a team from Cardiff and Warwick Universities.

27 May 2011

Interim analysis of AIM-HIGH study affirms positive impact of Niaspan on HDL and triglyceride lipid values

The National Heart, Lung and Blood Institute (NHLBI), a division of the National Institutes of Health (NIH), disclosed results from an interim analysis of the AIM-HIGH clinical trial.

27 May 2011

Possible defense for community-acquired pneumonia among the elderly

Community-acquired pneumonia is the leading cause of infectious death among the elderly. Newly published research from The University of Texas Health Science Center San Antonio suggests why older people are vulnerable and offers a possible defense.

27 May 2011

NHLBI stops AIM-HIGH combination clinical trial in high blood cholesterol

The National Heart, Lung, and Blood Institute of the National Institutes of Health has stopped a clinical trial studying a blood lipid treatment 18 months earlier than planned. The trial found that adding high dose, extended-release niacin to statin treatment in people with heart and vascular disease, did not reduce the risk of cardiovascular events, including heart attacks and stroke.

27 May 2011

4SC to present pre-clinical data on vidofludimus in systemic lupus erythematosus at EULAR 2011

4SC AG, a discovery and development company of targeted small molecule drugs for autoimmune and cancer diseases, will present pre-clinical data on vidofludimus - its lead small-molecule drug candidate against autoimmune diseases - in systemic lupus erythematosus at EULAR 2011, Europe's largest scientific conference on rheumatic diseases, in London, UK, from May 25-28, 2011.

27 May 2011

Positive results from CEL-SCI's LEAPS H1N1-activated dendritic cells trial in mice

CEL-SCI Corporation today announced the positive results of efficacy studies in mice of L.E.A.P.S.TM H1N1 activated dendritic cells to treat the H1N1 virus.

27 May 2011

Longer looks: Stem cells, vaccinating against addictive drugs, the GOP's budget hatchet man

Krista and Tatiana are not like most other sets of twins. They are connected at their heads, where their skulls merge under a mass of shaggy brown bangs. The girls run and play and go down their backyard slide, but whatever they do, they do together, their heads forever inclined toward each other's, their neck muscles strong and sinuous from a never-ending workout. Twins joined at the head — the medical term is craniopagus — are extremely rare.

27 May 2011

MAP Pharmaceuticals submits LEVADEX NDA to FDA for treatment of migraine in adults

MAP Pharmaceuticals, Inc. today announced that it has submitted a New Drug Application to the United States Food and Drug Administration for LEVADEX orally inhaled migraine drug for the potential acute treatment of migraine in adults.

27 May 2011

Boehringer Ingelheim's new afatinib-cetuximab phase Ib data in NSCLC presented at ASCO 2011

Boehringer Ingelheim Pharmaceuticals, Inc. will present new phase Ib data at the 2011 American Society of Clinical Oncology annual meeting in Chicago that indicates combining its investigational therapy afatinib with cetuximab at the maximum tested dose controlled disease in all (n=22) treated epidermal growth factor receptor (EGFR)-mutation positive patients with non-small cell lung cancer who developed acquired resistance to treatment with a reversible EGFR tyrosine kinase inhibitor.

26 May 2011

Studies find antibiotics overused for children with asthma, urinary tract infections

Two new studies led by researchers at the University of California, San Francisco have found some antibiotics may be overused for children with asthma and urinary tract infections.

26 May 2011

Pulmonx announces new clinical data of Zephyr endobronchial valve in emphysema

Pulmonx Inc. has announced new clinical data from its Chartis multi-center study, presented at the American Thoracic Society's 2011 International Conference.

25 May 2011

Vuvuzela unhealthy in more ways than one: Study

According to health experts, Vuvuzelas - the horns used by football fans celebrating last year's World Cup - not only cause noise pollution but may also spread diseases. According to a new study published in PLoS One journal it is seen that a short burst on the instrument creates a spittle shower similar to a sneeze, travelling at a four million droplets a second. Authors write that in crowded venues one person blowing a Vuvuzela could infect many others with airborne illness like the flu or TB.

24 May 2011

Galectin-3 research uncovers new use for Modified Citrus Pectin in cardiovascular, heart disease

In a new important research study out of the UK, scientists found that the specific form of Modified Citrus Pectin developed by Isaac Eliaz, M.D. interrupts deadly kidney fibrosis by binding to galectin-3 molecules, decreasing the effects of inflammation and fibrosis in acute kidney injury.

24 May 2011

Scientists mimic dyskeratosis congenita through study of undifferentiated iPS cells

A rare genetic disease called dyskeratosis congenita, caused by the rapid shortening of telomeres, can be mimicked through the study of undifferentiated induced pluripotent stem cells, according to new findings from the Stanford University School of Medicine.

24 May 2011

National Council on Skin Cancer Prevention 'Don't Fry Day' campaign to encourage sun safety awareness

Despite skin cancer's being largely preventable, it remains by far the most common type of cancer in the United States. There are over two million new cases of skin cancer diagnosed annually, which is more than new cases of breast, prostate, lung and colon cancers combined.

24 May 2011

Lungs News and Research

New imaging method using fluorescent nanotubes can peer clearly into living mouse's innards

New positive Cimzia phase IIIb study data on rheumatoid arthritis presented at EULAR meeting

Cholesterol drug Niaspan fails to protect heart: Study

High blood pressure becoming more common in young adults: Study

Efficacy of Abbott cholesterol drug in question

Bacteria that infect cystic fibrosis patients could help combat MRSA

Interim analysis of AIM-HIGH study affirms positive impact of Niaspan on HDL and triglyceride lipid values

Possible defense for community-acquired pneumonia among the elderly

NHLBI stops AIM-HIGH combination clinical trial in high blood cholesterol

4SC to present pre-clinical data on vidofludimus in systemic lupus erythematosus at EULAR 2011

Positive results from CEL-SCI's LEAPS H1N1-activated dendritic cells trial in mice

Longer looks: Stem cells, vaccinating against addictive drugs, the GOP's budget hatchet man

MAP Pharmaceuticals submits LEVADEX NDA to FDA for treatment of migraine in adults

Boehringer Ingelheim's new afatinib-cetuximab phase Ib data in NSCLC presented at ASCO 2011

Studies find antibiotics overused for children with asthma, urinary tract infections

Pulmonx announces new clinical data of Zephyr endobronchial valve in emphysema

Vuvuzela unhealthy in more ways than one: Study

Galectin-3 research uncovers new use for Modified Citrus Pectin in cardiovascular, heart disease

Scientists mimic dyskeratosis congenita through study of undifferentiated iPS cells

National Council on Skin Cancer Prevention 'Don't Fry Day' campaign to encourage sun safety awareness

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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