Chromosome 7 News and Research

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Humans normally have 46 chromosomes in each cell, divided into 23 pairs. Two copies of chromosome 7, one copy inherited from each parent, form one of the pairs. Chromosome 7 spans about 159 million DNA building blocks (base pairs) and represents more than 5 percent of the total DNA in cells.

Identifying genes on each chromosome is an active area of genetic research. Because researchers use different approaches to predict the number of genes on each chromosome, the estimated number of genes varies. Chromosome 7 likely contains about 1,150 genes.

Genes on chromosome 7 are among the estimated 20,000 to 25,000 total genes in the human genome.

Plymouth researchers receive grant to develop effective therapy for Huntington's disease

Huntington's disease is an hereditary disorder of the nervous system caused by a faulty gene on chromosome four. The faulty gene leads to nerve damage in the area of the brain resulting in gradual physical, mental and emotional changes. Those born to a parent with Huntington's disease have a 50:50 chance of developing it, and there is currently no cure.

9 Apr 2015

Researchers analyze false-positive results from new prenatal genetic screens

Prenatal blood screening for extra or missing chromosomes in the fetus might give false-positive results if the mother's genome contains more than the usual number of certain DNA segments.

6 Apr 2015

Research may point to new paradigms in diagnosis, treatment of aggressive cancers

All living things--from dandelions to reindeer--evolve over time. Cancer cells are no exception, and are subject to the two overarching mechanisms described by Charles Darwin: chance mutation and natural selection.

3 Apr 2015

Study: 'Open' stem cell chromosomes hold great promise for treating liver, pancreas diseases

Stem cells hold great promise for treating a number of diseases, in part because they have the unique ability to differentiate, specializing into any one of the hundreds of cell types that comprise the human body.

2 Apr 2015

New prenatal test introduced for detecting Down’s Syndrome

A new prenatal test for Down’s Syndrome may be more effective at diagnosing the condition than the standard screening that is currently used, suggests a study published in the New England Journal of Medicine.

2 Apr 2015

Novel molecule inhibits cancer-causing transcription factors

A novel molecule designed by scientists at the University of Massachusetts Medical School and the University of Virginia inhibits progression of a hard-to-treat form of recurring acute myeloid leukemia (AML) in patient tissue.

2 Apr 2015

Big data helps discover gephyrin protein's connection in human history

Big data: It's a term we read and hear about often, but is hard to grasp. Computer scientists at Washington University in St. Louis' School of Engineering & Applied Science tackled some big data about an important protein and discovered its connection in human history as well as clues about its role in complex neurological diseases.

30 Mar 2015

Research: Common bacteria poised to become antibiotic-resistant superbugs

Antibiotic resistance is poised to spread globally among bacteria frequently implicated in respiratory and urinary infections in hospital settings, according to new research at Washington University School of Medicine in St. Louis.

30 Mar 2015

Study: Blood test may help diagnose Fragile X syndrome related disorders in women

A blood test may shed new light on Fragile X syndrome related disorders in women, according to a new study published in the March 25, 2015, online issue of Neurology, the medical journal of the American Academy of Neurology. Fragile X is the most common inherited form of intellectual disability and the most frequent genetic cause of autism.

30 Mar 2015

Iceland paint a genomic picture for an entire nation

Researchers in Iceland have published the largest ever studies of whole-genome data and effectively deduced the genetic code of “an entire nation.”

26 Mar 2015

Mount Sinai researchers reprogram blood cells into iPSCs to study genetic origins of MDS

Induced pluripotent stem cells (iPSCs) -- adult cells reprogrammed back to an embryonic stem cell-like state--may better model the genetic contributions to each patient's particular disease. In a process called cellular reprogramming, researchers at Icahn School of Medicine at Mount Sinai have taken mature blood cells from patients with myelodysplastic syndrome (MDS) and reprogrammed them back into iPSCs to study the genetic origins of this rare blood cancer.

26 Mar 2015

Fourth-line bosutinib ‘appropriate’ after prior CML treatment failure, intolerance

A Spanish study suggests that bosutinib can help improve or maintain response in patients with chronic myeloid leukaemia after treatment failure of three previous tyrosine kinase inhibitors.

24 Mar 2015

Male genetic diversity declined due to wealth, power rather than `survival of fittest`

The DNA you inherit from your parents contributes to the physical make-up of your body -- whether you have blue eyes or brown, black hair or red, or are male or female.

23 Mar 2015

RMANJ acquires IVF New Jersey

Reproductive Medicine Associates of New Jersey, a world-renowned leader in the field of infertility, today announced the strategic acquisition of IVF New Jersey Fertility and Gynecology Center, one of the largest fertility centers in New Jersey.

18 Mar 2015

Genetic markers may help decide who benefits from aspirin, NSAIDs in lowering risk of colorectal cancer

An Indiana University cancer researcher and her colleagues have identified genetic markers that may help determine who benefits from regular use of aspirin and other nonsteroidal anti-inflammatory drugs for lowering one's risk of developing colorectal cancer.

18 Mar 2015

Super-resolution microscopes reveal the link between genome packaging and cell pluripotency

In 1953 Watson and Crick first published the discovery of the double helix structure of the DNA. They were able to visualize the DNA structure by means of X-Ray diffraction. Techniques, such as electron microscopy, allowed scientists to identify nucleosomes, the first and most basic level of chromosome organisation

13 Mar 2015

Researchers discover gene associated with congenital anomaly of urinary tract

An interdisciplinary team of researchers under the direction of the University of Bonn Hospital have discovered a gene which is associated with a rare congenital anomaly of the urinary tract called classic bladder exstrophy.

13 Mar 2015

Understanding genetic machinery that drives malignant pediatric adrenocortical tumors

In an advance that could lead to better identification of malignant pediatric adrenocortical tumors, and ultimately to better treatment, researchers have mapped the "genomic landscape" of these rare childhood tumors. Their genomic mapping has revealed unprecedented details, not only of the aberrant genetic and chromosomal changes that drive the cancer, but the sequence of those changes that trigger it.

10 Mar 2015

Rare, aggressive subtype of pediatric acute lymphoblastic leukemia has surprisingly few mutations

The St. Jude Children's Research Hospital--Washington University Pediatric Cancer Genome Project reports that a highly aggressive form of leukemia in infants has surprisingly few mutations beyond the chromosomal rearrangement that affects the MLL gene. The findings suggest that targeting the alteration is likely the key to improved survival.

9 Mar 2015

USF researchers uncover how malaria-related parasites spread at explosive rates

A University of South Florida College of Public Health professor and his team of researchers have become the first to uncover part of the mysterious process by which malaria-related parasites spread at explosive and deadly rates inside humans and other animals.

5 Mar 2015

Chromosome 7 News and Research

Plymouth researchers receive grant to develop effective therapy for Huntington's disease

Researchers analyze false-positive results from new prenatal genetic screens

Research may point to new paradigms in diagnosis, treatment of aggressive cancers

Study: 'Open' stem cell chromosomes hold great promise for treating liver, pancreas diseases

New prenatal test introduced for detecting Down’s Syndrome

Novel molecule inhibits cancer-causing transcription factors

Big data helps discover gephyrin protein's connection in human history

Research: Common bacteria poised to become antibiotic-resistant superbugs

Study: Blood test may help diagnose Fragile X syndrome related disorders in women

Iceland paint a genomic picture for an entire nation

Mount Sinai researchers reprogram blood cells into iPSCs to study genetic origins of MDS

Fourth-line bosutinib ‘appropriate’ after prior CML treatment failure, intolerance

Male genetic diversity declined due to wealth, power rather than `survival of fittest`

RMANJ acquires IVF New Jersey

Genetic markers may help decide who benefits from aspirin, NSAIDs in lowering risk of colorectal cancer

Super-resolution microscopes reveal the link between genome packaging and cell pluripotency

Researchers discover gene associated with congenital anomaly of urinary tract

Understanding genetic machinery that drives malignant pediatric adrenocortical tumors

Rare, aggressive subtype of pediatric acute lymphoblastic leukemia has surprisingly few mutations

USF researchers uncover how malaria-related parasites spread at explosive rates

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Exploring the G:Box and for high-quality imaging

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