Lungs News and Research

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Asymptomatic patients do not benefit from CT angiography screening

Coronary computed tomographic angiography, which can detect plaque buildup in heart vessels, is sometimes used as a screening tool to assess the risk for a heart attack. However, the usefulness of the test on low-risk patients who do not have coronary symptoms, such as chest pain, has been unclear.

24 May 2011

New device can combat hypothermia in wounded soldiers

A Biomedical Engineering Senior Design team at Stevens Institute of Technology is working with the U.S. Army and New Jersey physicians to develop a new device to combat hypothermia among wounded soldiers.

24 May 2011

Altor receives NHLBI SBIR grant to complete ALT-836 second Phase 2 trial in ALI/ARDS

Altor BioScience Corporation announced today that the National Heart Lung and Blood Institute has awarded Altor a Small Business Innovation Research Phase II Competing Renewal Grant. The award of over $3.18 MM over three years will support Altor's efforts to complete a second Phase 2 clinical trial using ALT-836, an antibody-based tissue factor antagonist, as a therapy to treat patients with infection-induced acute lung injury/acute respiratory distress syndrome.

24 May 2011

Scientists discover genetic regions that affect severity of cystic fibrosis

A team of international researchers, including Case Western Reserve University School of Medicine, have discovered regions of the genome that affect the severity of the genetic disease cystic fibrosis, the most common lethal genetic disease affecting children in North America.

24 May 2011

Journal of Clinical Oncology publishes Exelixis' cabozantinib phase 1 trial results in lymphoma

Exelixis, Inc. today announced the results of the phase 1 clinical trial of cabozantinib in patients with advanced solid tumors or lymphoma have been published in the current issue of the Journal of Clinical Oncology.

24 May 2011

Terminally ill missing out on palliative care: Survey reports

According to two new surveys, increased hospital admissions in the last three months of life could be of little benefit to dying people and are in contrast to the wishes of many.

23 May 2011

Expert review of respiratory medicine on pulmonary hypertension

Pulmonary hypertension (PH) is a rare, often incurable lung disorder that affects individuals of all ages, races and ethnic backgrounds. In the recent 4th World Conference on Pulmonary Hypertension held by the WHO, PH was classified into five groups based on its causes, highlighting both the magnitude of conditions associated with PH and how little we know of the etiology in many cases.

23 May 2011

New technique can detect minute traces of tumoral DNA in biological fluids

It will perhaps be possible, in the near future, to detect cancer by a simple blood or urine test. In fact, biologists from CNRS, Inserm, Paris Descartes and Strasbourg universities have developed a technique capable of detecting minute traces of tumoral DNA present in the biological fluids of patients suffering from cancer.

23 May 2011

Researchers discover new genes that influence severity of cystic fibrosis

Johns Hopkins Institute for Genetic Medicine researchers working as part of the North American Cystic Fibrosis Consortium have discovered two regions of the genome that affect the severity of cystic fibrosis, a genetic condition that causes scarring throughout the body, affecting most notably the pancreas and lungs.

23 May 2011

Blood stored in banks may undergo changes and damage

New research provides evidence for significant differences between new and old red blood cells used for transfusions and could provide a cheap, rapid and effective way to monitor the quality of blood supplies.

21 May 2011

Bristol-Myers Squibb to present abstracts on oncology compounds at ASCO 2011 Annual Meeting

Bristol-Myers Squibb Company, a leading global BioPharma company in oncology, today announced that more than 95 scientific abstracts on its approved and investigational oncology compounds will be featured at the 47th Annual Meeting of the American Society of Clinical Oncology in Chicago from June 3-7.

21 May 2011

Technology to determine most effective chemotherapy treatment wins first prize in UC Davis Big Bang! competition

A technology that could allow cancer specialists to better determine the most effective chemotherapy treatment for a given patient won the $10,000 in first prize money in the 11th annual Big Bang! Business Plan Competition at the University of California, Davis. The contest is run by MBA students in the Graduate School of Management.

20 May 2011

EMA CHMP recommends positive opinion for marketing authorization of Amgen's XGEVA

Amgen today announced that the Committee for Medicinal Products for Human Use of the European Medicines Agency has recommended a positive opinion for the marketing authorization of XGEVA (denosumab) for the prevention of skeletal-related events (pathological fracture, radiation to bone, spinal cord compression or surgery to bone) in adults with bone metastases from solid tumors.

20 May 2011

VBL to present positive VB-111 preclinical data in metastatic lung cancer at 14th ASGCT

VBL Therapeutics, a clinical-stage biotechnology company committed to the development of novel treatments for immune-inflammatory diseases and cancer, today announced that it will present preclinical data demonstrating VB-111's potential synergy and additive therapeutic effect when administered in combination with the conventional chemotherapy cancer treatments.

20 May 2011

Simple home-based colon cancer screening test can prevent many unnecessary deaths in Canada

Use of a simple, at-home screening test by Canadians can prevent many unnecessary colorectal cancer deaths, according to a special report about colorectal cancer in Canadian Cancer Statistics 2011 released today by the Canadian Cancer Society, in collaboration with the Public Health Agency of Canada and Statistics Canada.

19 May 2011

Experts to develop pioneering tool for personalised asthma and COPD therapy

A team of international experts, led by a University of Leicester researcher based at Glenfield Hospital, is set to develop a pioneering tool to help tailor the treatment of asthma and chronic obstructive pulmonary disease as part of a new EU project.

19 May 2011

Aspirin, simvastatin not effective in combating pulmonary artery hypertension

Despite their beneficial effects in treating heart disease, neither aspirin nor simvastatin appear to offer benefit to patients suffering from pulmonary artery hypertension (PAH), according to a National Institutes of Health (NIH)-funded study conducted at four U.S. medical centers. This was the first NIH-funded randomized clinical trial (RCT) in PAH.

19 May 2011

Mpex, Synteract partner for cystic fibrosis fundraising event

Synteract, Inc., a full-service, global contract research organization, and Mpex Pharmaceuticals, a biopharmaceutical company developing new therapies to combat the growing issue of antibiotic resistance, have partnered for the second annual Great Strides fundraiser to benefit cystic fibrosis.

19 May 2011

New data on personalized approaches for skin, ovarian and lung cancer to be presented at ASCO meeting

Genentech, a member of the Roche Group, today announced that data showing new personalized approaches for people with skin and lung cancer, plus new data with Avastin in ovarian cancer, will be presented at the 47th Annual Meeting of the American Society of Clinical Oncology.

18 May 2011

Restrictive gadolinium-based contrast agent guidelines help prevent nephrogenic systemic fibrosis

A simple blood test may help prevent a serious complication associated with a contrast agent commonly used in MRI exams, according to a study published in the July issue of Radiology.

18 May 2011

Lungs News and Research

Asymptomatic patients do not benefit from CT angiography screening

New device can combat hypothermia in wounded soldiers

Altor receives NHLBI SBIR grant to complete ALT-836 second Phase 2 trial in ALI/ARDS

Scientists discover genetic regions that affect severity of cystic fibrosis

Journal of Clinical Oncology publishes Exelixis' cabozantinib phase 1 trial results in lymphoma

Terminally ill missing out on palliative care: Survey reports

Expert review of respiratory medicine on pulmonary hypertension

New technique can detect minute traces of tumoral DNA in biological fluids

Researchers discover new genes that influence severity of cystic fibrosis

Blood stored in banks may undergo changes and damage

Bristol-Myers Squibb to present abstracts on oncology compounds at ASCO 2011 Annual Meeting

Technology to determine most effective chemotherapy treatment wins first prize in UC Davis Big Bang! competition

EMA CHMP recommends positive opinion for marketing authorization of Amgen's XGEVA

VBL to present positive VB-111 preclinical data in metastatic lung cancer at 14th ASGCT

Simple home-based colon cancer screening test can prevent many unnecessary deaths in Canada

Experts to develop pioneering tool for personalised asthma and COPD therapy

Aspirin, simvastatin not effective in combating pulmonary artery hypertension

Mpex, Synteract partner for cystic fibrosis fundraising event

New data on personalized approaches for skin, ovarian and lung cancer to be presented at ASCO meeting

Restrictive gadolinium-based contrast agent guidelines help prevent nephrogenic systemic fibrosis

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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