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Scientists explore antigenic imprinting in SARS-CoV-2

A recently published study compared monoclonal RBD antibody responses induced by SARS-CoV-2 Beta variant infections to antibodies induced by the ancestral virus in immunologically naive subjects.

12 Jul 2022

How do symptom burden and viral kinetics differ between healthy, vaccinated adults infected with either Delta, Omicron BA.1, or BA.2?

Researchers assessed the symptom profiles present in SARS-CoV-2 Delta, Omicron BA1. and BA.2-infected patients.

12 Jul 2022

Researchers report a non-canonical RNA secondary structure present in monkeypox virus variants

Researchers described the evolutionary profile of the monkeypox virus.

12 Jul 2022

The impact of gene amplification in virus adaptation through intermediate hosts

Researchers assessed the impact of gene amplification on cross-species adaptation.

12 Jul 2022

Comparison of complaints following second and third COVID mRNA vaccine doses

In a recent article posted to the medRxiv* preprint server, investigators in Norway and Sweden compared medical complaints after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection following second and third dose SARS-CoV-2 vaccinations.

12 Jul 2022

Scientists investigate impact of SARS-CoV-2 RBD mutations across variants

In a recent study posted to the medRxiv* pre-print server, Australian researchers comprehensively investigated the impact of 39 receptor-binding-domain (RBD) mutations in six severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern (VOCs) and variants of interest (VOIs).

12 Jul 2022

Early detection of SARS-CoV-2 variants via wastewater sequencing uncovers cryptic transmission

In a recent study published in the Nature journal, researchers assessed severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission using wastewater sequencing.

11 Jul 2022

Experimental model reveals possible causes and treatments for long-COVID

In a recent study published in the journal Science Translational Medicine, researchers characterized long-term pulmonary consequences of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) mouse-adapted strain (MA10) infection in BALB/c laboratory mice.

11 Jul 2022

Nanoparticle vaccine could protect against animal viruses including future SARS-CoV-2 variants

A recent study published in the Science journal depicted that mosaic receptor-binding domain (RBD) nanoparticles immunize from diverse sarbecovirus challenges, including severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), among animal models.

8 Jul 2022

Research assesses antigenic co-evolution of SARS-CoV-2 variants

In a recent study posted to the bioRxiv* preprint server, researchers analyzed antigenic variety across the significant severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants, like Omicron lineages.

8 Jul 2022

Stillbirths and preterm births significantly lower in COVID vaccinated women

In a recent study posted to the medRxiv* preprint server, researchers determined the association between messenger ribonucleic acid (mRNA) coronavirus disease 2019 (COVID-19) vaccinations and perinatal outcomes including congenital abnormalities, stillbirths, and premature births in Australia.

8 Jul 2022

Antibodies transmitted through breast milk persist six months after COVID mRNA vaccination

Researchers describe the effects of COVID-19 vaccines in lactating mothers and relates their antibody response to the protection of their children.

7 Jul 2022

Broadness of neutralizing antibodies to sarbecoviruses depends on priming conditions

In a recent study under review at the Nature Portfolio journal and currently available on the Research Square* preprint server, researchers identified immune priming conditions that generated broadly neutralizing antibody (nAb) responses and assessed immunity post-third dose of coronavirus disease 2019 (COVID-19) vaccines such as BNT126b2 or Coronavac vaccines after two homologous doses of BNT126b2 or Coronavac vaccines.

7 Jul 2022

Vaccination against smallpox efficiently protects against monkeypox infection

In a new study, researchers assessed the existing information regarding monkeypox infections.

6 Jul 2022

Beyond COVID-19: the potential future applications of mRNA vaccines

Researchers described the production, mechanisms, and potential applications of mRNA vaccines.

6 Jul 2022

Intrahost genetic diversity and evolution of the SARS-CoV-2 B.1.517 lineage during chronic infection of an immunocompromised individual

Researchers investigated the intrahost evolution and genetic diversity of the SARS-CoV-2 B.1.517 variant in an immunosuppressed person with chronic COVID-19.

6 Jul 2022

How does hybrid immunity shape humoral immune response to SARS-CoV-2?

In a recent study posted to the medRxiv* preprint server, researchers illustrated that hybrid severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) immunity widens effective humoral signatures of SARS-CoV-2 vaccinations.

6 Jul 2022

Healthy, cancer, and immunosuppressed patients all benefit from COVID boosters

In a recent study posted to the medRxiv* pre-print server, researchers developed a mechanistic mathematical model to predict the course of vaccine-induced immunity in healthy and immunosuppressed patients for the long term, exceeding the time frames for which clinical data is currently available.

5 Jul 2022

Novel inhalable COVID-19 vaccine

A recent study published in the Nature Biomedical Engineering journal illustrated a novel inhalable SARS-CoV-2 vaccine candidate centered on exosomes (Exos) coupled with recombinant severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) receptor-binding domain (RBD).

5 Jul 2022

Next-generation SARS-CoV-2 nucleocapsid-based vaccines may provide optimal protection against infection

In a new study,researchers suggested the inclusion of nucleocapsid protein in vaccines against SARS-CoV-2.

5 Jul 2022

Ribonucleic Acid News and Research

Scientists explore antigenic imprinting in SARS-CoV-2

How do symptom burden and viral kinetics differ between healthy, vaccinated adults infected with either Delta, Omicron BA.1, or BA.2?

Researchers report a non-canonical RNA secondary structure present in monkeypox virus variants

The impact of gene amplification in virus adaptation through intermediate hosts

Comparison of complaints following second and third COVID mRNA vaccine doses

Scientists investigate impact of SARS-CoV-2 RBD mutations across variants

Early detection of SARS-CoV-2 variants via wastewater sequencing uncovers cryptic transmission

Experimental model reveals possible causes and treatments for long-COVID

Nanoparticle vaccine could protect against animal viruses including future SARS-CoV-2 variants

Research assesses antigenic co-evolution of SARS-CoV-2 variants

Stillbirths and preterm births significantly lower in COVID vaccinated women

Antibodies transmitted through breast milk persist six months after COVID mRNA vaccination

Broadness of neutralizing antibodies to sarbecoviruses depends on priming conditions

Vaccination against smallpox efficiently protects against monkeypox infection

Beyond COVID-19: the potential future applications of mRNA vaccines

Intrahost genetic diversity and evolution of the SARS-CoV-2 B.1.517 lineage during chronic infection of an immunocompromised individual

How does hybrid immunity shape humoral immune response to SARS-CoV-2?

Healthy, cancer, and immunosuppressed patients all benefit from COVID boosters

Novel inhalable COVID-19 vaccine

Next-generation SARS-CoV-2 nucleocapsid-based vaccines may provide optimal protection against infection

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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