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SBIR grant awarded to develop treatment for alcoholic liver disease-associated hepatorenal syndrome

The Institute of Human Virology (IHV) at the University of Maryland School of Medicine and MitoPower LLC were awarded an SBIR (Small Business Innovation Research) grant of up to $6.5 million over five years from the National Institutes of Health's National Institute on Alcohol Abuse and Alcoholism.

9 Nov 2021

Enhanced neutralizing antibody and T-cell responses by DNA-based vaccine encoding SARS-CoV-2 spike protein

Researchers from VaxiGen have been investigating the potential for a DNA vaccine boost to VP vaccines against coronavirus disease 2019.

9 Nov 2021

Hemin as a potential therapy for COVID-19

The current study explores the antiviral activity of HO-1 induced by hemin against SARS-CoV-2 and attempts to describe the mechanism of its anti-viral action.

8 Nov 2021

Researchers explain why decaying SARS-CoV-2 antibodies in blood are not a problem after vaccination

A new study published in the preprint bioRxiv* server suggests vaccination helps to inflate the number of somatic hypermutations acquired by B cells. The increase in somatic hypermutations allows for an accumulation of highly matured bone marrow plasma cells.

8 Nov 2021

Rapid antibody response induced by mRNA COVID vaccines in mice

A new study posted in the bioRxiv* preprint server used mouse models to investigate how mRNA vaccines elicit a rapid antibody response. Their findings show two different mRNA vaccines successfully boost antibody levels — IL-5, IL-6, and MCP-1 —5 days after administration.

7 Nov 2021

Pacific oyster as a weapon against SARS-CoV-2

According to an article published in the journal Reviews in Medical Virology, the effectiveness of mollusc-derived antiviral agents has been proven in many different laboratory and animal studies, while its efficacy against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has also been proposed by recent in silico studies.

7 Nov 2021

Oral SARS-CoV-2 Mpro inhibitor for therapeutic use

A new study describes a new small molecule compound that has shown impressive safety, tolerability, and bioavailability against SARS-CoV-2.

7 Nov 2021

Montana’s Governor nixed a kids’ vaccine campaign, so health officials plan their own

Montana Gov. Greg Gianforte's administration quashed plans for a public service campaign to promote covid-19 vaccinations for eligible teenagers over the summer, a former state health official said.

3 Nov 2021

Humoral and cell-mediated immunity six months post BNT162b2 vaccination

A recent study has evaluated vaccine-induced humoral and cellular immunity against SARS-CoV-2 six months post BNT162b2 (Pfizer-BioNTech) vaccination.

2 Nov 2021

Trends in SARS-CoV-2 seroprevalence in Massachusetts

A new study reported findings from a retrospective, de-identified and systematic survey of SARS-CoV-2 seroprevalence among childbearing women in Massachusetts.

2 Nov 2021

Labs with no one to run them: Why public health workers are fleeing the field

There were days, nights and weekends in the early months of the pandemic when Denise Von Bargen was the only person running covid tests at the public health lab in Ventura County. She once had eight or nine employees to assist her, but, one by one, they had all retired or left for other jobs.

2 Nov 2021

Curcumin, a bioactive component of turmeric, effectively neutralizes SARS-CoV-2 in vitro

The researchers investigated the neutralizing activity of turmeric root extract, curcumin-containing capsules, and pure curcumin against SARS-CoV-2.

1 Nov 2021

Microtubule regulatory protein inhibits early HIV-1 infection, study finds

Northwestern Medicine investigators have discovered that a microtubule regulatory protein inhibits early HIV type 1 (HIV-1) infection, according to findings published in Proceedings of the National Academy of Sciences.

1 Nov 2021

Structural and molecular contributions to understanding antibody recognition of pathogenic viruses

A new review discusses how molecular and structural biology have contributed to our understanding of antibody recognition of HIV-1, SARS-CoV-2, and Zika.

1 Nov 2021

Areas with higher 1968 influenza pandemic mortality have lower COVID-19 deaths

A new study demonstrates the influence of prior infectious outbreaks in a large population on succeeding pandemic outcomes.

31 Oct 2021

Prompt procurement and rapid pace of vaccination likely to have a greater impact than vaccine efficacy

For low- and middle-income countries, a COVID-19 vaccination program built on prompt procurement, effective on-the-ground distribution, and a rapid pace of vaccination (the total number of doses given daily) is likely to have a greater public health impact than one focused on relatively small differences in vaccine efficacy, according to a study led by researchers at Massachusetts General Hospital.

30 Oct 2021

HIV News and Research

SBIR grant awarded to develop treatment for alcoholic liver disease-associated hepatorenal syndrome

Enhanced neutralizing antibody and T-cell responses by DNA-based vaccine encoding SARS-CoV-2 spike protein

Hemin as a potential therapy for COVID-19

Researchers explain why decaying SARS-CoV-2 antibodies in blood are not a problem after vaccination

Rapid antibody response induced by mRNA COVID vaccines in mice

Pacific oyster as a weapon against SARS-CoV-2

Oral SARS-CoV-2 Mpro inhibitor for therapeutic use

Montana’s Governor nixed a kids’ vaccine campaign, so health officials plan their own

Humoral and cell-mediated immunity six months post BNT162b2 vaccination

Trends in SARS-CoV-2 seroprevalence in Massachusetts

Labs with no one to run them: Why public health workers are fleeing the field

Curcumin, a bioactive component of turmeric, effectively neutralizes SARS-CoV-2 in vitro

Microtubule regulatory protein inhibits early HIV-1 infection, study finds

Structural and molecular contributions to understanding antibody recognition of pathogenic viruses

Areas with higher 1968 influenza pandemic mortality have lower COVID-19 deaths

Prompt procurement and rapid pace of vaccination likely to have a greater impact than vaccine efficacy

NIH study identifies distinct mechanisms of long-term HIV control in two people after treatment disruption

Study unravels how cells protect against influenza A viruses

Panel of broadly neutralizing SARS-CoV-2 nanobodies for immune assay application

Taking lessons in molecular therapeutics from earthworms to combat COVID

Shaping the Future of Neuroscience: A Conversation with Atlas Antibodies on the MolBoolean™ and the Impact of SfN 2024

How the Arts Reshape Brain Function: Susan Magsamen on the Future of Neuroaesthetics

Inside the Alzheimer's Association: Dr. Heather Snyder on Driving Research and Collaboration

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