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Scientists discover way to target immune system to shrink tumors in mice

St. Jude Children's Research Hospital scientists have discovered a way to target the immune system to shrink or eliminate tumors in mice without causing autoimmune problems. Researchers also found evidence that the same mechanism may operate in humans. The study was published today in the advance online edition of Nature.

5 Aug 2013

Atossa Genetics: Many American women still not aware of breast cancer risk

Virtually all American women are aware that the pink ribbon is the symbol of breast cancer awareness. Despite this near-universal recognition, it is still a sad fact that plenty of women do not truly appreciate the extent to which they are at risk for breast cancer.

3 Aug 2013

Plymouth researcher awarded Young Investigator Award by Children's Tumor Foundation

Dr. Lu Zhou, a member of a team of researchers at Plymouth University Peninsula Schools of Medicine and Dentistry whose area of expertise is brain tumours, has been awarded a fellowship by the Children's Tumor Foundation.

3 Aug 2013

Castle Biosciences to present DecisionDx-Melanoma test data at Summer Academy Meeting of AAD

Castle Biosciences Inc. announced that data from studies of its DecisionDx-Melanoma test are being presented today at the Summer Academy Meeting of the American Academy of Dermatology. The validation data confirm previous studies showing that the gene expression profile test is a strong independent predictor for classifying which Stage I or II non-metastatic cutaneous melanoma patients will likely recur.

2 Aug 2013

ImmunoGen reports net loss of $21.9 million in Q4 2013

ImmunoGen, Inc., a biotechnology company that develops anticancer therapeutics using its Targeted Antibody Payload antibody-drug conjugate technology, today reported financial results for the three-month period and fiscal year ended June 30, 2013. ImmunoGen also provided guidance for its 2014 fiscal year and an update on the Company.

2 Aug 2013

Cancer biomarker tests undervalued by doctors and patients, authors say

There's a major roadblock to creating personalized cancer care. Doctors need a way to target treatments to patients most likely to benefit and avoid treating those who will not. Tumor biomarker tests can help do this.

2 Aug 2013

Study shows blocking dietary sugar in tumor cells may reduce cancer risk and progression

Blocking dietary sugar and its activity in tumor cells may reduce cancer risk and progression, according to researchers from the Icahn School of Medicine. The study, conducted in fruit flies and published in the journal Cell, provides insight as to why metabolism-related diseases such as diabetes or obesity are associated with certain types of cancer, including pancreatic, breast, liver, and colon cancers

2 Aug 2013

Scientists prevent cell sleep to reduce chance of tumor recurrence

An international research team led by University of Pittsburgh Cancer Institute (UPCI) scientists discovered that by preventing cancer cells from entering a state of cellular sleep, cancer drugs are more effective, and there is a lower chance of cancer recurrence.

2 Aug 2013

ImmunoGen announces FDA approval of IMGN289 Investigational New Drug

ImmunoGen, Inc. (Nasdaq: IMGN), a biotechnology company that develops novel anticancer therapeutics using its Targeted Antibody Payload (TAP) ADC technology, today announced that the Company's x (IND) application has been accepted by the US FDA and is now active.

2 Aug 2013

Study reveals epigenetic mechanisms contribute to chronic disease susceptibility prior to birth

If you think stress is killing you, you may be right, but what you don't know is that stress might have harmed your health even before you were born. In a new report appearing in the August 2013 issue of The FASEB Journal, Harvard researchers find that epigenetic disruptions, which are associated with chronic disease later in life, are already common at birth.

2 Aug 2013

UCLA researchers develop treatment approach for breast cancer metastasized to brain

Researchers at UCLA's Jonsson Comprehensive Cancer Center (JCCC) have successfully combined cellular therapy and gene therapy in a mouse model system to develop a viable treatment strategy for breast cancer that has metastasized, or spread, to the patient's brain.

2 Aug 2013

Researchers hope to exploit unique metabolic profile of cancer

Researchers from the University of Illinois at Chicago College of Medicine have identified a characteristic unique to cancer cells in an animal model of cancer -- and they believe it could be exploited as a target to develop new treatment strategies.

2 Aug 2013

Study: New therapeutic approach to treat prostate cancer

A study in the Journal of Biological Chemistry identifies a new therapeutic approach to treat prostate cancer. Conducted at Cincinnati Children's Hospital Medical Center, the research shows that expression of the FoxM1 protein is essential for prostate cancer to develop in mouse models. The study appears in the journal's Aug. 2 edition.

2 Aug 2013

Research aims to provide physicians a more targeted approach to treating ER+ breast cancer

The most commonly diagnosed form of breast cancer, termed estrogen receptor positive or ER+, accounts for the largest percentage of breast cancer deaths each year. Research by scientists at the HudsonAlpha Institute for Biotechnology and the University of Alabama at Birmingham Comprehensive Cancer Center aims to provide physicians a more targeted approach to treating ER+ breast cancer.

2 Aug 2013

Using the immune system to control cancer: an interview with Dr. Jedd Wolchok, MD, PhD, Ludwig Center at MSKCC

Cancer immunotherapy aims to recruit a patient’s immune system to recognize cancer as foreign and dangerous and to remove it from the body, as it would an infection.

1 Aug 2013

Novocure uses NovoTTF therapy to treat first recurrent glioblastoma tumor patient

Novocure today announced that Dr. Tatsunori Okamaura, MD, Ph.D., of the Kashiwaba Neurosurgical Hospital in Sapporo, Japan has treated the first patient in Japan with alternating electric field therapy.

1 Aug 2013

Researchers identify novel approach to enhance tissue repair and organ regeneration

Because most human tissues do not regenerate spontaneously, advances in tissue repair and organ regeneration could benefit many patients with a wide variety of medical conditions.

1 Aug 2013

Cedars-Sinai physicist receives William D. Coolidge Award for pioneering work in radiation oncology

Benedick Fraass, PhD, FAAPM, FASTRO, FACR, received the highest honor from the American Association of Physicists in Medicine — the William D. Coolidge Award — for his distinguished career achievements in medical physics, including his pioneering work in radiation oncology.

1 Aug 2013

Nektar completes enrollment in NKTR-102 BEACON trial in patients with metastatic breast cancer

Nektar Therapeutics (NASDAQ: NKTR) today announced that enrollment is complete in the pivotal clinical study of etirinotecan pegol (NKTR-102) in patients with metastatic breast cancer.

31 Jul 2013

Researchers receive NIH grant to identify potential links between cancer risk and automobile traffic

A professor from the University of Miami School of Business Administration, along with collaborators from the Yale School of Public Health, has received a $453,000 grant from the National Cancer Institute of the National Institutes of Health to identify potential links between cancer risk and the proximity of homes to heavy automobile traffic.

31 Jul 2013

Tumor News and Research

Scientists discover way to target immune system to shrink tumors in mice

Atossa Genetics: Many American women still not aware of breast cancer risk

Plymouth researcher awarded Young Investigator Award by Children's Tumor Foundation

Castle Biosciences to present DecisionDx-Melanoma test data at Summer Academy Meeting of AAD

ImmunoGen reports net loss of $21.9 million in Q4 2013

Cancer biomarker tests undervalued by doctors and patients, authors say

Study shows blocking dietary sugar in tumor cells may reduce cancer risk and progression

Scientists prevent cell sleep to reduce chance of tumor recurrence

ImmunoGen announces FDA approval of IMGN289 Investigational New Drug

Study reveals epigenetic mechanisms contribute to chronic disease susceptibility prior to birth

UCLA researchers develop treatment approach for breast cancer metastasized to brain

Researchers hope to exploit unique metabolic profile of cancer

Study: New therapeutic approach to treat prostate cancer

Research aims to provide physicians a more targeted approach to treating ER+ breast cancer

Using the immune system to control cancer: an interview with Dr. Jedd Wolchok, MD, PhD, Ludwig Center at MSKCC

Novocure uses NovoTTF therapy to treat first recurrent glioblastoma tumor patient

Researchers identify novel approach to enhance tissue repair and organ regeneration

Cedars-Sinai physicist receives William D. Coolidge Award for pioneering work in radiation oncology

Nektar completes enrollment in NKTR-102 BEACON trial in patients with metastatic breast cancer

Researchers receive NIH grant to identify potential links between cancer risk and automobile traffic

Shaping the Future of Neuroscience: A Conversation with Atlas Antibodies on the MolBoolean™ and the Impact of SfN 2024

How the Arts Reshape Brain Function: Susan Magsamen on the Future of Neuroaesthetics

Inside the Alzheimer's Association: Dr. Heather Snyder on Driving Research and Collaboration

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