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Studying the Proteome and Human Diseases using Mass Spectrometry

An interview with Amanda Hummon, discussing how mass spectrometry can be used to analyze the proteome and how this can help with the study of human disease.

From Pittcon 13 Aug 2020

Simple urine test could speed up adrenal cancer diagnosis

Using a simple urine test alongside routine imaging for patients with adrenal masses could speed up adrenal cancer diagnosis, improving patient's prognosis and reducing the need for invasive diagnostic procedures, a new multi-centre study published in The Lancet Diabetes & Endocrinology has found.

23 Jul 2020

Researchers discover marine alga from Kiel Fjord as potential remedy against infections, skin cancer

Healing with the help of marine organisms is no utopia. Already 12 life-saving drugs, e.g. against cancer, have been developed from marine organisms and their symbiotic microbiota.

2 Jul 2020

Direct structural link between SARS-CoV-2 and essential fatty acid

Now, a new study published on the preprint server bioRxiv in June 2020 reports the discovery of a novel free fatty acid (FFA) binding pocket on the SARS-CoV-2 virus that could explain in part the viral effects of hyperinflammation, immune modulation, and membrane structure.

21 Jun 2020

A metabolomics approach to detect objective biomarkers of ASD

In a paper published online this week in Autism Research, scientists at NeuroPointDX, a division of Stemina Biomarker Discovery, Inc., in collaboration with researchers at the UC Davis MIND Institute and academic and clinical institutions across the country, report new findings from the Children's Autism Metabolome Project or CAMP.

18 Jun 2020

A 'multi-omics' approach to the development of drugs against COVID-19

A new study published on the preprint server medRxiv* in May 2020 reports a multi-omics approach that could make it easier to develop drugs that are effective against COVID-19.

12 May 2020

Prebiotics could help improve sleep and boost stress resilience

Think dietary fiber is just for digestive health? Think again.

3 Mar 2020

Exercise causes changes to some of the body's metabolites, research finds

New research finds that exercise causes changes to some of the body's metabolites-;small molecules the body produces during metabolism.

7 Nov 2019

Metabolite profiling during diagnosis helps identify poor treatment outcomes in ALL

The survival of patients with pediatric acute lymphoblastic leukemia (ALL) has significantly improved in the last several decades. However, novel strategies to identify cases that are likely to respond poorly to treatment are still needed.

24 Oct 2019

Rice bran supplement for infants provides more nutrients, reduces diarrhea

Malnutrition is prevalent on a global scale and has numerous negative consequences for children during the first five years of life. For some children, it can mean struggling with health issues for life or a higher risk of death among those under five years of age.

8 Oct 2019

Bruker announces novel phenomics solutions at Metabolomics 2019

At Metabolomics 2019, Bruker highlights innovative MS and NMR systems, and novel high-value solutions for molecular phenomics and clinical metabolomics.

From Bruker Life Sciences Mass Spectrometry 26 Jun 2019

Bacteriophage can have a profound impact on the dynamics of gut microbiome, study finds

The gut microbiome is a complex, interconnected ecosystem of species. And, like any ecosystem, some organisms are predators and some are prey.

7 Jun 2019

UAB study reveals how enzyme lipoxygenase drives heart failure after heart attacks

Heart failure after a heart attack is a global epidemic leading to chronic heart failure pathology. About 6 million people in the United States and 23 million worldwide suffer from this end-stage disease that involves dysfunction of the heart, a change that clinicians call cardiac remodeling.

31 May 2019

Researchers identify metabolic signatures to help diagnose, treat and prevent cervical cancer

Researchers at the University of Arizona have completed the first-of-its-kind study that could aid in the treatment, diagnosis and prevention of cervical cancer by identifying cervicovaginal metabolic signatures, or "fingerprints" that distinguish patients with HPV, pre-cancerous cervical conditions and cancer.

15 May 2019

Scientists develop small fluorophores for tracking metabolites in living cells

Living cells can react to disturbances with a changed metabolism, but direct observation of trafficking metabolites in live cells is difficult.

30 Apr 2019

National Institutes of Health awards grant to MSU professors for research on neurodegenerative disease

A research collaboration between three Montana State University faculty members recently received a grant to help fund their study on the connection between a rare genetic neurological disease and metabolism, the human gut microbiome and degeneration of the nervous system.

30 Nov 2018

NeuroPointDX launches NPDX AA test to identify metabolic subtypes associated with autism

NeuroPointDX, a division of Stemina Biomarker Discovery, today announced the commercial launch of its NPDX AA test, which identifies metabolic subtypes associated with autism spectrum disorder.

1 Nov 2018

Metabolome tests could be new way to measure obesity and health

The link between obesity and health problems may seem apparent. People who are obese are at higher risk of type 2 diabetes, liver disease, cancer, and heart disease.

12 Oct 2018

Scientists find new way to predict obesity-related disease risk

Scientists at Scripps Research and collaborating corporate and academic partners have found a new way to use distinct molecular "signatures" from people with obesity to predict risk of developing diabetes and cardiovascular disease, an advance that could broaden the way doctors and scientists think about diagnosing and treating disease.