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Forced elongation of telomeres promotes differentiation of cancer cells

Researchers from the Japanese Foundation for Cancer Research in Tokyo have discovered that forced elongation of telomeres (extensions on the end of chromosomes) promotes the differentiation of cancer cells, probably reducing malignancy, which is strongly associated with a loss of cell differentiation.

28 Jun 2013

MorphoSys, Celgene agree to jointly develop MOR202 for patients with multiple myeloma

MorphoSys AG and Celgene Corporation today announced an agreement to jointly develop MOR202 globally and to co-promote MOR202 in Europe.

27 Jun 2013

Low-molecular-weight PAHs promote conditions for cancer growth

Tobacco smoke, diesel exhaust and oil combustion carry polycyclic aromatic hydrocarbons - PAHs that are known to cause cancer. But of these PAHs, the obviously dangerous high-molecular-weight PAHs like benzo[a]pyrene (BaP) have received the vast majority of research attention.

26 Jun 2013

Johns Hopkins students design device to reduce need for repeated breast cancer surgeries

When a breast tumor is detected, many women opt to have a lumpectomy, which is surgery designed to remove the diseased tissue while preserving the breast. But during this procedure, doctors cannot learn right away whether all of the cancerous tissue has been removed, with no microscopic signs that cancer cells were left behind.

26 Jun 2013

UC professor receives Biemann Medal from ASMS for significant achievement in mass spectrometry

Yinsheng Wang, a professor of chemistry at the University of California, Riverside, has received the Biemann Medal, awarded by the American Society for Mass Spectrometry (ASMS) to an individual early in his or her career in recognition of significant achievement in basic or applied mass spectrometry.

26 Jun 2013

Findings suggest BRAF-mutant colon tumor cells may be less sensitive to the effect of aspirin

In 2 large studies, the association between aspirin use and risk of colorectal cancer was affected by mutation of the gene BRAF, with regular aspirin use associated with a lower risk of BRAF-wild-type colorectal cancer but not with risk of BRAF-mutated cancer, findings that suggest that BRAF-mutant colon tumor cells may be less sensitive to the effect of aspirin, according to a study in the June 26 issue of JAMA.

26 Jun 2013

Verastem announces initiation of VS-4718 Phase 1 trial in patients with advanced cancer

Verastem, Inc., focused on discovering and developing drugs to treat cancer by the targeted killing of cancer stem cells, announced the initiation of a Phase 1 trial of VS-4718, a novel, small molecule inhibitor of focal adhesion kinase, in patients with advanced cancer.

26 Jun 2013

Study: Active surveillance does not appear to be good idea for black men with prostate cancer

A Johns Hopkins study of more than 1,800 men ages 52 to 62 suggests that African-Americans diagnosed with very-low-risk prostate cancers are much more likely than white men to actually have aggressive disease that goes unrecognized with current diagnostic approaches.

26 Jun 2013

Sarah Cannon Research Institute opens enrollment in Phase I clinical study with MORAb-066

Morphotek, Inc., a subsidiary of Eisai Inc., announced today that the Sarah Cannon Research Institute in Nashville, Tennessee has opened enrollment in a Phase I clinical study with MORAb-066 in patients with advanced or metastatic breast, pancreatic, colorectal or non-small cell lung cancer (adenocarcinoma) malignancies.

26 Jun 2013

New streamlined method harnesses tumor-infiltrating lymphocytes to improve outcomes

Jamie K. Teer, Ph.D., assistant member of the Cancer Biology and Evolution Program at Moffitt Cancer Center, and colleagues have developed a new streamlined method to rapidly identify the genetic changes in small protein fragments unique to melanoma cancer cells.

26 Jun 2013

Research paper reveals Cav-1 protein's role in prostate tumor microenvironment

Researchers at the Cedars-Sinai Samuel Oschin Comprehensive Cancer Institute have uncovered for the first time the vital role a popular protein plays in the stroma, the cell-lined area outside of a prostate tumor.

26 Jun 2013

Seattle Genetics collaborates with Bayer HealthCare for new antibody-drug conjugate

Seattle Genetics, Inc. today announced that it has entered into a new antibody-drug conjugate (ADC) collaboration with Bayer HealthCare (Bayer). Under the latest relationship, Bayer will pay upfront and option exercise fees of up to $20 million for worldwide rights to utilize Seattle Genetics' auristatin-based ADC technology with antibodies to several oncology targets.

25 Jun 2013

Thermo Fisher Scientific and Newman-Lakka Institute collaborate to develop new diagnostic approaches for personalized cancer treatment

Thermo Fisher Scientific Inc., the world leader in serving science, and the Newman-Lakka Institute for Personalized Cancer Care at Floating Hospital for Children at Tufts Medical Center, announced an intended collaboration for research and development of new methods to detect and track circulating biomarkers in blood.

25 Jun 2013

Research may lead to new screening method for oral cancer and HPV

Research being carried out at the University of Notre Dame and its affiliated Harper Cancer Research Institute may lead to the development of a rapid, cost-effective means of screening for oral cancers and the human papillomavirus.

25 Jun 2013

CytRx reaches targeted enrollment in aldoxorubicin Phase 2b study for treatment of soft tissue sarcoma

CytRx Corporation, a biopharmaceutical research and development company specializing in oncology, announced that it has reached the targeted enrollment of 105 evaluable patients in its international Phase 2b clinical trial with aldoxorubicin as a first-line treatment for soft tissue sarcoma.

25 Jun 2013

Rural women with breast cancer less likely to receive radiation therapy after lumpectomy

Rural women with breast cancer are less likely than their urban counterparts to receive recommended radiation therapy after having a lumpectomy, a breast-sparing surgery that removes only tumors and surrounding tissue, a study by Mayo Clinic and others found.

25 Jun 2013

Researchers test modified dendritic cells in patients with melanoma

In this issue of the Journal of Clinical Investigation, researchers led by Scott Pruitt at Duke University and Merck Research Laboratories report on a human clinical trial in which modified dendritic cells, a component of the immune system, were tested in patients with melanoma.

25 Jun 2013

Investigators uncover connection between tumor metabolic process and progression of kidney cancer

Investigators in The Cancer Genome Atlas (TCGA) Research Network have uncovered a connection between how tumor cells use energy from metabolic processes and the aggressiveness of the most common form of kidney cancer, clear cell renal cell carcinoma (ccRCC).

24 Jun 2013

Researchers provide new revelations about intricate pathways involved in turning on T cells

A major study from researchers at the La Jolla Institute for Allergy and Immunology provides new revelations about the intricate pathways involved in turning on T cells, the body's most important disease-fighting cells, and was published today in the prestigious scientific journal Nature.

24 Jun 2013

Discovery of cells movement inside body may provide information to scientists about disease mechanism s

A new discovery about how cells move inside the body may provide scientists with crucial information about disease mechanisms such as the spread of cancer or the constriction of airways caused by asthma.

24 Jun 2013

Tumor News and Research

Forced elongation of telomeres promotes differentiation of cancer cells

MorphoSys, Celgene agree to jointly develop MOR202 for patients with multiple myeloma

Low-molecular-weight PAHs promote conditions for cancer growth

Johns Hopkins students design device to reduce need for repeated breast cancer surgeries

UC professor receives Biemann Medal from ASMS for significant achievement in mass spectrometry

Findings suggest BRAF-mutant colon tumor cells may be less sensitive to the effect of aspirin

Verastem announces initiation of VS-4718 Phase 1 trial in patients with advanced cancer

Study: Active surveillance does not appear to be good idea for black men with prostate cancer

Sarah Cannon Research Institute opens enrollment in Phase I clinical study with MORAb-066

New streamlined method harnesses tumor-infiltrating lymphocytes to improve outcomes

Research paper reveals Cav-1 protein's role in prostate tumor microenvironment

Seattle Genetics collaborates with Bayer HealthCare for new antibody-drug conjugate

Thermo Fisher Scientific and Newman-Lakka Institute collaborate to develop new diagnostic approaches for personalized cancer treatment

Research may lead to new screening method for oral cancer and HPV

CytRx reaches targeted enrollment in aldoxorubicin Phase 2b study for treatment of soft tissue sarcoma

Rural women with breast cancer less likely to receive radiation therapy after lumpectomy

Researchers test modified dendritic cells in patients with melanoma

Investigators uncover connection between tumor metabolic process and progression of kidney cancer

Researchers provide new revelations about intricate pathways involved in turning on T cells

Discovery of cells movement inside body may provide information to scientists about disease mechanism s

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