Lungs News and Research

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Current progress in SARS-CoV-2 vaccine candidates

In a new study, researchers illustrated the current progress and obstacles in COVID-19 vaccine development.

7 Mar 2022

The relative dynamics of infection with the Delta and Omicron SARS-CoV-2 variants in aged and young Syrian hamsters

Researchers demonstrated the relative pathogenicity of SARS-CoV-2 Omicron and Delta variants of concern in Syrian hamsters.

7 Mar 2022

Disruption of sleep and circadian rhythm can increase the chances of contracting a virus

A recent study explores the effect of sleep and circadian rhythm dispersion on mouse lung transcriptome after six of hours sleep deprivation.

6 Mar 2022

Omicron-specific mRNA vaccine generates immune responses in mice, hamsters and Macaques

Researchers develop an Omicron variant mRNA vaccine that is be more potent in generating nAbs as compared to other available vaccines.

6 Mar 2022

Study may pave the way for better multiple sclerosis drugs

Investigators from Weill Cornell Medicine and Memorial Sloan Kettering Cancer Center have discovered how a drug for multiple sclerosis interacts with its targets, a finding that may pave the way for better treatments.

4 Mar 2022

Researchers identify genetic link between lymphatic disorder and stillbirth

In a world first discovery, South Australian researchers have identified a genetic mutation responsible for a lymphatic disorder that may cause stillbirth or severe, chronic disease in affected children.

4 Mar 2022

Angiotensin-converting enzyme 2-based mutant decoy effectively reduces COVID-19 in mice

Researchers engineered a mutant ACE2 decoy that effectively protected human lung epithelia from SARS-CoV-2 infection by competitively binding to its spike protein.

3 Mar 2022

Study establishes that a low dose SARS-CoV-2 infection increases risk of pneumococcal coinfection

A new study published on the bioRxiv* preprint server has evaluated bacterial susceptibility during SARS-CoV-2 infection.

3 Mar 2022

Assessing the potential of IFNa subtypes in suppressing SARS-CoV-2

A recent study analyzes IFNa subtypes for their therapeutic potential against SARS-CoV-2 and identified the underlying immune signatures and mechanisms.

3 Mar 2022

Study shows the viability of lung transplants in patients with COVID-19-associated ARDS

Patients with COVID-19-associated acute respiratory distress syndrome who received lung transplants had similar outcomes, compared to transplant patients without COVID-19, according to a Northwestern Medicine study published in JAMA.

2 Mar 2022

Adenosine receptor agonists provide therapeutic target in mouse SARS-CoV-2 infection

A new study describes the efficacy of adenosine receptor agonists in the treatment of SARS-CoV-2 infection.

2 Mar 2022

Potential of a SARS-CoV-2 immunoPET approach to study COVID-19 dynamics in total body in rhesus macaques

In a recent study an immunoPET technique that the authors were using to analyze SIV was adapted to evaluate the spatiotemporal dynamics of SARS-CoV-2 infection in a rhesus macaque model.

2 Mar 2022

New type of drug delivery vehicle mimics the properties of a red blood cell

From the liver to the kidneys to the lungs, the human body is equipped with many levels of filters, which protect the body from harmful outside materials. But this system also has its downsides. Critically important drugs such as chemotherapy or multiple sclerosis treatments are also foreign materials, so the body filters out a large portion of these drugs – up to 90%, in some cases.

2 Mar 2022

Penn Medicine receives $12.3 million NIH grant to study FLASH radiotherapy for cancer

With more than $12 million in new funding from the National Institutes of Health, the Abramson Cancer Center at the University of Pennsylvania will build on its preclinical research of an emerging form of radiation that provides ultra-fast doses-;of under a second, compared to several minutes with conventional radiation-;and shows promise of greater protection of normal tissue, thereby minimizing toxic effects to the body.

1 Mar 2022

U of U Health researchers lead a $22-million nationwide clinical trial for rare brain disorder

University of Utah Health researchers are leading a five-year, $22-million nationwide clinical trial for NMDA receptor encephalitis––a type of autoimmune encephalitis that prompts the immune system to mistakenly attack the brain, causing confusion, memory loss, seizures, and symptoms similar to bipolar disorder and other psychiatric conditions.

1 Mar 2022

Vapers, hookah smokers may expose the nose and sinuses to more emissions than cigarette smokers

People who smoke e-cigarette and hookah are more than twice as likely to exhale particles through their nose compared with people who smoke cigarettes, who favor exhaling the emissions from their mouth, a new study shows.

1 Mar 2022

Study finds MK-4482 inhibits replication of multiple SARS-CoV-2 variants of concern in Syrian hamster COVID-19 model

Researchers found that an antiviral drug, was effective against SARS-CoV-2 variants, including the recently emerged Omicron variant, in Syrian hamsters.

1 Mar 2022

COVID-19 severity is correlated with body composition

In a recent study posted to the medRxiv* preprint server, researchers assessed the effect of changes in the abdominal well-being and physique on coronavirus disease 2019 (COVID-19) severity using magnetic resonance imaging (MRI).

28 Feb 2022

Microorganisms hindering cancer therapy have more influence than the beneficial ones, study says

Melanoma patients receiving therapy that helps their immune system kill cancer cells respond to treatment differently depending on the types of microbes in their gut, and new research suggests the microorganisms hindering therapy have more influence than the beneficial ones.

28 Feb 2022

Exercise may help reduce the risk of blood clots in patients with aggressive form of NAFLD

Exercise may help certain patients with nonalcoholic fatty liver disease (NAFLD) reduce their risk of developing blood clots, according to a new study by Penn State College of Medicine researchers.

28 Feb 2022

Lungs News and Research

Current progress in SARS-CoV-2 vaccine candidates

The relative dynamics of infection with the Delta and Omicron SARS-CoV-2 variants in aged and young Syrian hamsters

Disruption of sleep and circadian rhythm can increase the chances of contracting a virus

Omicron-specific mRNA vaccine generates immune responses in mice, hamsters and Macaques

Study may pave the way for better multiple sclerosis drugs

Researchers identify genetic link between lymphatic disorder and stillbirth

Angiotensin-converting enzyme 2-based mutant decoy effectively reduces COVID-19 in mice

Study establishes that a low dose SARS-CoV-2 infection increases risk of pneumococcal coinfection

Assessing the potential of IFNa subtypes in suppressing SARS-CoV-2

Study shows the viability of lung transplants in patients with COVID-19-associated ARDS

Adenosine receptor agonists provide therapeutic target in mouse SARS-CoV-2 infection

Potential of a SARS-CoV-2 immunoPET approach to study COVID-19 dynamics in total body in rhesus macaques

New type of drug delivery vehicle mimics the properties of a red blood cell

Penn Medicine receives $12.3 million NIH grant to study FLASH radiotherapy for cancer

U of U Health researchers lead a $22-million nationwide clinical trial for rare brain disorder

Vapers, hookah smokers may expose the nose and sinuses to more emissions than cigarette smokers

Study finds MK-4482 inhibits replication of multiple SARS-CoV-2 variants of concern in Syrian hamster COVID-19 model

COVID-19 severity is correlated with body composition

Microorganisms hindering cancer therapy have more influence than the beneficial ones, study says

Exercise may help reduce the risk of blood clots in patients with aggressive form of NAFLD

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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