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Study finds Omicron sublineage BA.2 is less pathogenic in rodent models than prior SARS-CoV-2 variants

Researchers evaluated the pathogenicity and replication potential of SARS-CoV-2 VOC Omicron lineage, BA.2 in immunocompetent mice and hamsters.

28 Feb 2022

Antibiotics provide no benefit in preventing recurrent wheezing in infants hospitalized with RSV

Antibiotics provide no benefit in preventing future recurrent wheezing in babies hospitalized with respiratory syncytial virus (RSV), according to a new study led by Washington University School of Medicine in St. Louis. And there is some evidence that antibiotics may make wheezing worse.

27 Feb 2022

ECMO shortage linked to the death of young, healthy COVID-19 patients

Nearly 90 percent of COVID-19 patients who qualified for, but did not receive, ECMO (extracorporeal membrane oxygenation) due to a shortage of resources during the height of the pandemic died in the hospital, despite being young with few other health issues, according to a study published in the American Journal of Respiratory and Critical Care Medicine.

25 Feb 2022

Application of various nanoparticle-capsulated siRNA as therapeutics for SARS-CoV-2 infection

In a review published in the International Journal of Molecular Sciences, researchers have been reviewing the use of siRNAs to target coronaviruses.

25 Feb 2022

Interleukin-1 Receptor-Like 2 cytokine accomplishes a dual effect in inflammation and healing

The Interleukin-1 Receptor-Like 2 (IL-1RL2) cytokine can promote inflammatory diseases and have a role in controlling infection.

24 Feb 2022

Melatonin as a safe and potentially life-saving treatment for COVID-19

A new study discusses the possible role of melatonin, an antioxidant and anti-inflammatory agent, in treating COVID-19.

24 Feb 2022

Study shows SARS-CoV-2 hijacks mitochondrial transcriptional machinery resulting in organ failure and death

In a new study, researchers studied SARS-CoV-2 infection on the transcription of mitochondrial oxidative phosphorylation, glycolysis, nutrient sensing, and stress response genes.

24 Feb 2022

Edible egg-derived IgY antibodies against SARS-CoV-2 Omicron

A new study posted to the bioRxiv* preprint server reports on the development of anti-RBD immunoglobulin Y (IgY) antibodies from chicken eggs to block the binding of the viral RBD to human ACE2 receptors. This approach has several advantages since chicken egg-derived IgY can be edible and polyclonal can target multiple epitopes, enhancing neutralizing activity.

23 Feb 2022

First reported case of a cat infected with SARS-CoV-2 Delta AY.3 variant

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is hurting our loved ones — even those that walk on four legs. Researchers from the University of Pennsylvania documented the recovery of an 11-year old indoor housecat living in Delaware who first presented to the veterinary hospital after experiencing distressing gastrointestinal symptoms.

23 Feb 2022

Tiny lipid-based nanoparticles carry genetic instructions directly into the lungs

Researchers at the Tufts University School of Engineering are building a reputation for precision targeting in drug delivery.

23 Feb 2022

Novel AI tool can spot difficult-to-diagnose cardiac conditions

Physician-scientists in the Smidt Heart Institute at Cedars-Sinai have created an artificial intelligence (AI) tool that can effectively identify and distinguish between two life-threatening heart conditions that are often easy to miss: hypertrophic cardiomyopathy and cardiac amyloidosis.

23 Feb 2022

Cardiopulmonary limitations six months after surviving COVID-19

A recent prospective cohort study assessed the cardiopulmonary effects in patients six months after COVID-19 infection.

23 Feb 2022

SARS-Cov-2 reinfection in Syrian hamsters does not result in disease

Researchers have been investigating the reinfection of different SARS-CoV-2 variants in Syrian hamsters and found that this does not seem to result in disease or any significant pulmonary pathology.

23 Feb 2022

Exploring the potential of mosaic RBD nanoparticles to fight SARS-CoV-2

Researchers explore the potential of mosaic receptor-binding domain nanoparticles in protective immunity against SARS-CoV-2

22 Feb 2022

Breath tests can help detect traces of SARS-CoV-2 virus

Traces of the SARS-CoV-2 coronavirus that causes COVID-19 can be detected in microscopically small fluid droplets exhaled during a very short time span.

22 Feb 2022

Study provides a potent biparatopic antibody against all SARS-CoV-2 variants of concern

Researchers demonstrated the potent neutralization of SARS-CoV-2 VOCs, including Omicron by the biparatopic human heavy chain variable domain.

22 Feb 2022

Lung microbiome alterations and secondary-infections in lethal COVID-19

Researchers examined how an interplay of host and microbial factors weakened immunity leading to secondary infections in COVID-19-infected individuals.

22 Feb 2022

Mouse-adapted virus model to study persistent COVID induced lung disease

Researchers develop a mouse model to identify early biomarkers and test countermeasures needed to detect and prevent PASC.

21 Feb 2022

Climate change is sickening, literally!

A news study highlights the change in disease spread with climate change across the globe.

21 Feb 2022

Broad-spectrum antiviral activity of picolinic acid against SARS-CoV-2 and Influenza A virus

Researchers investigate the potential of picolinic acid (PA) as an anti-SARS-CoV-2 treatment option.

21 Feb 2022

Lungs News and Research

Study finds Omicron sublineage BA.2 is less pathogenic in rodent models than prior SARS-CoV-2 variants

Antibiotics provide no benefit in preventing recurrent wheezing in infants hospitalized with RSV

ECMO shortage linked to the death of young, healthy COVID-19 patients

Application of various nanoparticle-capsulated siRNA as therapeutics for SARS-CoV-2 infection

Interleukin-1 Receptor-Like 2 cytokine accomplishes a dual effect in inflammation and healing

Melatonin as a safe and potentially life-saving treatment for COVID-19

Study shows SARS-CoV-2 hijacks mitochondrial transcriptional machinery resulting in organ failure and death

Edible egg-derived IgY antibodies against SARS-CoV-2 Omicron

First reported case of a cat infected with SARS-CoV-2 Delta AY.3 variant

Tiny lipid-based nanoparticles carry genetic instructions directly into the lungs

Novel AI tool can spot difficult-to-diagnose cardiac conditions

Cardiopulmonary limitations six months after surviving COVID-19

SARS-Cov-2 reinfection in Syrian hamsters does not result in disease

Exploring the potential of mosaic RBD nanoparticles to fight SARS-CoV-2

Breath tests can help detect traces of SARS-CoV-2 virus

Study provides a potent biparatopic antibody against all SARS-CoV-2 variants of concern

Lung microbiome alterations and secondary-infections in lethal COVID-19

Mouse-adapted virus model to study persistent COVID induced lung disease

Climate change is sickening, literally!

Broad-spectrum antiviral activity of picolinic acid against SARS-CoV-2 and Influenza A virus

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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