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Experimental and computational synergy considered a promising approach in COVID-19 patients

Thanks to the large amount of -omics data becoming increasingly available, sophisticated computational models are developed for new fields such as immunology and the predictions they generate will help identify key molecules in inflammatory processes.

16 Dec 2021

Study: Pregnant women with disabilities have increased risk for birth complications and death

Pregnant women with disabilities have a much higher risk for severe pregnancy- and birth-related complications and death than other pregnant women, according to findings by researchers at the National Institutes of Health.

15 Dec 2021

SARS-CoV-2 VOCs dependent on IFITM2 for efficient infection establishment

Researchers demonstrate that the Alpha, Beta, Gamma, and Delta variants of SARS-CoV-2 require endogenous IFITM2 expression for efficient replication.

15 Dec 2021

Researchers spot signs of 'pre-resistance' in bacteria for the first time

Scientists have spotted signs of 'pre-resistance' in bacteria for the first time – signs that particular bacteria are likely to become resistant to antibiotics in the future – in a new study led by UCL and Great Ormond Street Hospital researchers.

15 Dec 2021

Hyperbaric oxygen treatment quickly resolves severe breathing difficulties in COVID-19 patients

High pressure (hyperbaric) oxygen resolves severe breathing difficulties in COVID-19 patients much more quickly than standard therapy, taking an average of 3 rather than 9 days, reveal the results of a small comparative clinical trial published online in Emergency Medicine Journal.

15 Dec 2021

Mattresses and mold removal: Medi-Cal to offer unconventional treatments to asthma patients

Growing up amid the dusty agricultural fields of the Central Valley, Ruby Marentes-Cabrera can't recall a time when it wasn't difficult to breathe.

15 Dec 2021

Driving up immunity at tumor site may help enhance immunotherapy treatments

Driving up the immune response at the site of a cancer tumor with nanotechnology may help enhance immunotherapy treatments in advanced stages of the disease, new research in mice suggests.

14 Dec 2021

Correlation between idiopathic pulmonary fibrosis and COVID-19

A new study investigates the genetic overlap between COVID-19 and idiopathic pulmonary fibrosis to identify possible shared biological mechanisms.

14 Dec 2021

11 exceptional recipients of the 2021 Lupus Innovation Award announced

The Lupus Research Alliance proudly announced today 11 research grant recipients in the U.S. and around the world of the 2021 Lupus Innovation Award which will fund wide ranging areas from probing the development and progression of lupus to pointing to potential personalized therapies.

14 Dec 2021

New mRNA vaccine platform provides stronger protection against SARS-CoV-2 delta variant

A group of researchers from various institutions developed a nucleoside-modified mRNA vaccine that encodes the SARS-CoV-2 N protein (mRNA-N) and is formulated in lipid nanoparticles for this investigation (LNP).

14 Dec 2021

Impact of tumor environments on susceptibility and course of disease in those infected with SARS-CoV-2

A review assessed the impact of "hot" vs. "cold" immune/tumor environments (and associated therapies) on susceptibility and disease course in subjects with these two types of tumors and infected with SARS-CoV-2 to decipher the mechanisms that drive these adverse outcomes in COVID-19 infected cancer patients.

13 Dec 2021

Sarcopenia and COVID-19

The present study attempts to investigate if sarcopenia, which is a condition where there is loss of skeletal muscle mass and function, may result in poor clinical outcomes in COVID-19 patients.

13 Dec 2021

Nasal infection drives lethal lung injury due to SARS-CoV-2 in mice

A new study demonstrates lethal infection of the olfactory epithelium in a mouse model that could help understand the mechanisms of COVID-19.

12 Dec 2021

Statistical model builds SARS-CoV-2 interactome with miRNAs, protein-coding genes, and co-infecting microbes

A team of researchers recently developed a statistical modeling method known as multiple-layer crosstalk (MLCrosstalk).

12 Dec 2021

Nasal vaccine provides broad-based protection against heterologous respiratory viruses in mice

The emergence of COVID-19 variants such as delta and omicron have sent scientists scrambling to determine whether existing vaccinations and boosters are still effective against new strains of SARS-Cov-2.

11 Dec 2021

Immunogenicity and safety of COVID-19 subunit vaccine Nanocovax in animal models

Researchers have developed Nanocovax, a COVID-19 subunit vaccine based on recombinant protein technology to produce the extracellular (soluble) portion of the S protein of SARS-CoV-2.

9 Dec 2021

Systemic sclerosis more common among Black children than previously thought

An immune disease that can damage vital organs – and is supposedly rare in young people – is more common than previously thought among Black children, a study suggests.

8 Dec 2021

Study shows how senescent cells can be an underlying cause of kidney damage

A study in mice by researchers at Georgetown Lombardi Comprehensive Cancer Center has found that stress and tissue damage initiated by angiotensin II, a molecule that is known to increase blood pressure and stiffening in the linings of blood vessels, leads to cellular senescence, a process by which a cell ages and permanently stops dividing but does not die.

8 Dec 2021

Researchers discover biomarker that could aid in early detection of high risk COVID-19 patients

Led by computational researchers from WEHI, in collaboration with The University of Queensland, Queensland University of Technology and Hospital Marcelino Champagnat in Brazil, the study used advanced spatial transcriptomic techniques to screen for genes associated with excessive inflammation in the lungs, a key indicator of severe COVID-19.

7 Dec 2021

Hypercoagulability of the blood responsible for cardiac thrombosis in COVID-19 patients

Researchers examined autopsy tissue samples of hearts from patients who died early in the COVID-19 pandemic.

7 Dec 2021

Lungs News and Research

Experimental and computational synergy considered a promising approach in COVID-19 patients

Study: Pregnant women with disabilities have increased risk for birth complications and death

SARS-CoV-2 VOCs dependent on IFITM2 for efficient infection establishment

Researchers spot signs of 'pre-resistance' in bacteria for the first time

Hyperbaric oxygen treatment quickly resolves severe breathing difficulties in COVID-19 patients

Mattresses and mold removal: Medi-Cal to offer unconventional treatments to asthma patients

Driving up immunity at tumor site may help enhance immunotherapy treatments

Correlation between idiopathic pulmonary fibrosis and COVID-19

11 exceptional recipients of the 2021 Lupus Innovation Award announced

New mRNA vaccine platform provides stronger protection against SARS-CoV-2 delta variant

Impact of tumor environments on susceptibility and course of disease in those infected with SARS-CoV-2

Sarcopenia and COVID-19

Nasal infection drives lethal lung injury due to SARS-CoV-2 in mice

Statistical model builds SARS-CoV-2 interactome with miRNAs, protein-coding genes, and co-infecting microbes

Nasal vaccine provides broad-based protection against heterologous respiratory viruses in mice

Immunogenicity and safety of COVID-19 subunit vaccine Nanocovax in animal models

Systemic sclerosis more common among Black children than previously thought

Study shows how senescent cells can be an underlying cause of kidney damage

Researchers discover biomarker that could aid in early detection of high risk COVID-19 patients

Hypercoagulability of the blood responsible for cardiac thrombosis in COVID-19 patients

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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