Receptor News and Research

RSS

Gender differences in renal and other genes contributing to blood pressure

Many common diseases exhibit gender bias and gender differences have been observed in the development of high blood pressure (hypertension) and heart (cardiovascular) disease.

9 Aug 2007

Inflammation from bacterial infections linked to preterm births and deaths

New findings from the mouse study holds potential to develop ways to curb the emotional and economic toll on families that lose babies to preterm labor and fetal death, said Han, a member of from the department of periodontics.

9 Aug 2007

Variant of the dopamine receptor gene may be associated with ADHD

A variant of the dopamine receptor gene may be associated with attention-deficit/hyperactivity disorder (ADHD) and with thinner tissue in areas of the brain that handle attention, but also appears associated with better clinical outcomes among individuals with the disorder, according to a report in the August issue of Archives of General Psychiatry , one of the JAMA/Archives journals.

7 Aug 2007

Brain areas that control attention thinnest in children with ADHD

Brain areas that control attention were thinnest in children with attention deficit hyperactivity disorder (ADHD) who carried a particular version of a gene in a study by the National Institutes of Health's (NIH) National Institute of Mental Health (NIMH).

7 Aug 2007

FDA approves maraviroc, an antiretroviral drug for use in adult HIV patients.

The U.S. Food and Drug Administration (FDA) has approved maraviroc, an antiretroviral drug for use in adult HIV patients. Maraviroc, sold under the trade name Selzentry, is the first in a new class of drugs designed to slow the advancement of HIV and received priority review by the FDA.

7 Aug 2007

Age-related hearing loss very common

For many people, hearing loss is part of aging. Hearing loss affects approximately one-third of people over age 65. Among people age 75 and older, 40 percent to 50 percent experience hearing loss.

7 Aug 2007

How the brain produces fever responses during infections

With the finding that fever is produced by the action of a hormone on a specific site in the brain, scientists have answered a key question as to how this adaptive function helps to protect the body during bacterial infection and other types of illness.

6 Aug 2007

Scientists make female mice act blokey!

By short-circuiting the sensory organ that detects the chemical cues mice use to attract mates, a team of Howard Hughes Medical Institute (HHMI) researchers has prompted female mice to behave like male mice in the throes of courtship.

6 Aug 2007

HMGB1 protein shown to act as an accelerator - activating the body's defenses

Toll-like receptors are the guard dogs of the immune system, sniffing out bacteria and viruses then activating the body's immune system for an attack on these invaders.

3 Aug 2007

Immunity in social amoeba suggests ancient beginnings

Finding an immune system in the social amoeba (Dictyostelium discoideum) is not only surprising but it also may prove a clue as to what is necessary for an organism to become multicellular, said the Baylor College of Medicine researcher who led the research that appears in the journal Science.

3 Aug 2007

Cognitive impairment link found in popular acid blockers

Long-term use of histamine2 receptor antagonists (H2A), one class of drugs that blocks stomach acid, may be associated with cognitive impairment in older African-American adults.

3 Aug 2007

Gene variation makes people with depression more likely to respond to the medication citalopram

A variation in a gene called GRIK4 appears to make people with depression more likely to respond to the medication citalopram (Celexa) than are people without the variation, a study by the National Institute of Mental Health (NIMH), part of the National Institutes of Health, has found.

3 Aug 2007

Delta-9-tetrahydrocannabinol opens door for virus that causes Kaposi's sarcoma

The major active component of marijuana could enhance the ability of the virus that causes Kaposi's sarcoma to infect cells and multiply, according to a team of researchers at Harvard Medical School.

2 Aug 2007

Colon cancer may benefit from hormone replacement therapy

Researchers at the Kimmel Cancer Center at Jefferson in Philadelphia have found new evidence suggesting that colon cancer is actually a disease of missing hormones that could potentially be treated by hormone replacement therapy.

2 Aug 2007

New risk genes for multiple sclerosis

Two new large-scale genomic studies have honed in on the main genetic pathway associated with multiple sclerosis (MS), while also uncovering new genetic variations in the disease and suggesting a possible link between MS and other autoimmune diseases.

1 Aug 2007

Europe approves MIRCERA to treat anaemia

Roche has announced that the European Commission has approved its innovative drug MIRCERA to treat anaemia associated with chronic kidney disease (CKD).

27 Jul 2007

FDA statement on gene therapy trial

On July 24, 2007 the U.S. Food and Drug Administration (FDA) was informed by Targeted Genetics Corporation of Seattle about the death of a patient who received an investigational gene therapy product in a clinical trial for the treatment of active inflammatory arthritis.

27 Jul 2007

Tonsil epithelial factors may influence oropharyngeal HIV transmission

Current research demonstrates that the tonsils may possess the necessary factors to act as a transmission site for the spread of HIV.

27 Jul 2007

Gut bacteria boost immune response to tumors

One potent, immune-based treatment for cancer is total body irradiation (TBI). This approach first depletes the body of the population of immune cells known as lymphocytes and then involves the adoptive transfer of tumor-specific T cells to the patient.

27 Jul 2007

Combination of blood pressure-lowering drugs stops loss of kidney function in rare genetic disease

A combination of two types of blood pressure-lowering drugs, an angiotensin-converting enzyme inhibitor (ACEI) plus an angiotensin-receptor blocker (ARB), added to enzyme replacement therapy (ERT) with agalsidase-beta (Fabrazyme, Genzyme Corporation, Cambridge, MA) is the first treatment shown to stop progressive loss of kidney function in patients with severe kidney involvement due to the rare genetic disorder Fabry disease, reports a study in the September Journal of the American Society of Nephrology.

26 Jul 2007