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Wyeth Pharmaceuticals receives FDA approvable for Bazedoxifene for the prevention of postmenopausal osteoporosis

Wyeth Pharmaceuticals has announced that the U.S. Food and Drug Administration (FDA) has issued an approvable letter for bazedoxifene, a selective estrogen receptor modulator (SERM) for the prevention of postmenopausal osteoporosis.

26 Apr 2007

Gene analysis explains ethnic differences in sensitivity to chemotherapy in lung cancer

Analysis of three genetic mechanisms that cause non-small cell lung cancer might explain why East Asians respond better than other ethnic groups to a certain type of chemotherapy, a team led by UT Southwestern Medical Center researchers has found.

25 Apr 2007

FDA panel recommends new HIV drug Maraviroc

Approval is expected to be granted in the United States for a new drug to treat HIV infections.

24 Apr 2007

Researchers identify key function of a molecule - wound healing in the skin

The skin is the largest organ of the human body. It protects against environmental influences and pathogens, regulates body temperature, and protects the body against dehydration.

24 Apr 2007

New understanding of schizophrenia

New research helps bridge an important gap in understanding schizophrenia, providing the best evidence to date that defects in the brain's white matter are a key contributor to the disease, which affects about 1 percent of people worldwide.

24 Apr 2007

Neither induced abortion nor miscarriage associated with breast cancer risk in premenopausal women

Neither induced abortion nor spontaneous abortion (miscarriage) appears to be associated with breast cancer risk in premenopausal women, according to a report in the April 23 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

24 Apr 2007

New methods for treating lung cancer cells that have become resistant to new anti-cancer agents

Researchers at the Ireland Cancer Center of University Hospitals Case Medical Center have developed methods for treating lung cancer cells that have become resistant to new anti-cancer agents.

24 Apr 2007

Klotho proteins important players in future therapies for diabetes, obesity and kidney disease

A relative of the anti-aging gene Klotho helps activate a hormone that can lower blood glucose levels in fat cells of mice, making it a novel target for developing drugs to treat human obesity and diabetes, UT Southwestern Medical Center researchers have found.

24 Apr 2007

New drug Maraviroc an alternative in the fight against HIV

An experimental AIDS drug appears to offer an alternative drug in the fight against HIV.

22 Apr 2007

Why bladder cancer hits more men than women

Scientists have discovered one of the reasons why bladder cancer is so much more prevalent in men than women: A molecular receptor or protein that is much more active in men than women plays a role in the development of the disease.

21 Apr 2007

M. D. Anderson wins $8.3-million to research environmental causes of major diseases

An $8.3-million federal grant to The University of Texas M. D. Anderson Cancer Center Science Park - Research Division addresses the complex interplay between such varied factors as genetics, diet, and environmental exposure to toxins that cause cancer, asthma, diabetes, cardiovascular and other diseases.

21 Apr 2007

Schering-Plough plans phase III trials for novel selective antiplatelet therapy

Schering-Plough Corporation has announced plans to initiate two global Phase III large-scale clinical outcomes trials for its novel selective oral antiplatelet therapy, the thrombin receptor antagonist (TRA) SCH 530348.

20 Apr 2007

New research may help identify patients most likely to benefit from cisplatin treatment

Researchers at the Massachusetts General Hospital (MGH) Cancer Center have identified a subgroup of hard-to-treat breast cancers that may be sensitive to the drug cisplatin, rarely used in the treatment of breast tumors.

20 Apr 2007

International Menopause Society reaction to report on breast cancer

A special report in the April 19 issue of the New England Journal of Medicine [1] brings initial analysis of data from the National Cancer Institute's Surveillance, Epidemiology and End Result (SEER) registries, showing that the incidence of breast cancer in women in the US fell by 6.7% in 2003, and stayed at the same level in 2004.

20 Apr 2007

Scent prediction test

The scent of lily of the valley hangs in the air for readers of the journal Angewandte Chemie: just rub the journal's cover and enjoy a lily-of-the-valley scent.

19 Apr 2007

Researchers find hepatitis A and hepatitis C attack same protein to block immune defenses

Despite the fact that they both infect the liver, the hepatitis A and hepatitis C viruses actually have very little in common.

19 Apr 2007

Researchers identify key gene that may be a marker of breast cancer metastasis

Despite the fact that they both infect the liver, the hepatitis A and hepatitis C viruses actually have very little in common.

19 Apr 2007

Researchers finds meth receptor that could lead to therapy

A recently discovered signaling system in the brain has just been shown to be turned on by methamphetamine, an Oregon Health & Science University study found.

19 Apr 2007

New discoveries about stem cells in leukemia, breast and colon cancer

Recent discoveries about the role of stem cells in cancer have altered the landscape of cancer research. With each new study, scientists are learning more about cancer-initiating properties of stem cells at organ sites and throughout the body.

19 Apr 2007

Decrease in breast cancer incidence linked to drop in HRT

A special report in the April 19, 2007 edition of The New England Journal of Medicine concludes that the sharp decline in breast-cancer incidence in 2003, followed by a relative stabilization at a lower rater in 2004, is most likely related to the first report of the Women's Health Initiative (WHI).

19 Apr 2007

Receptor News and Research

Wyeth Pharmaceuticals receives FDA approvable for Bazedoxifene for the prevention of postmenopausal osteoporosis

Gene analysis explains ethnic differences in sensitivity to chemotherapy in lung cancer

FDA panel recommends new HIV drug Maraviroc

Researchers identify key function of a molecule - wound healing in the skin

New understanding of schizophrenia

Neither induced abortion nor miscarriage associated with breast cancer risk in premenopausal women

New methods for treating lung cancer cells that have become resistant to new anti-cancer agents

Klotho proteins important players in future therapies for diabetes, obesity and kidney disease

New drug Maraviroc an alternative in the fight against HIV

Why bladder cancer hits more men than women

M. D. Anderson wins $8.3-million to research environmental causes of major diseases

Schering-Plough plans phase III trials for novel selective antiplatelet therapy

New research may help identify patients most likely to benefit from cisplatin treatment

International Menopause Society reaction to report on breast cancer

Scent prediction test

Researchers find hepatitis A and hepatitis C attack same protein to block immune defenses

Researchers identify key gene that may be a marker of breast cancer metastasis

Researchers finds meth receptor that could lead to therapy

New discoveries about stem cells in leukemia, breast and colon cancer

Decrease in breast cancer incidence linked to drop in HRT

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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