Receptor News and Research

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Why your teenager is so vile!

Researchers in the U.S. say they may have found a reason for the erratic mood swings of teenagers.

12 Mar 2007

Gene that prevents cancer also controls the skin's suntanning machinery

"The p53 tumor suppressor is commonly mutated in human cancer," explained David Fisher, director of the Melanoma Program in Medical Oncology at Dana-Farber Cancer Institute. "Now, we've found that it plays a role in the skin's tanning response."

8 Mar 2007

Mayo Clinic tests engineered measles virus against multiple myeloma

Mayo Clinic Cancer Center has opened a new Phase I clinical trial testing an engineered measles virus against multiple myeloma, a cancer of the bone marrow that currently has no cure. This is the third of a series of molecular medicine studies in patients testing the potential of measles to kill cancer.

5 Mar 2007

New clues may explain why Graves' disease attacks muscle tissue behind eyes

UCLA researchers have uncovered new clues that may explain why Graves' disease (GD) attacks the muscle tissue behind the eyes, often causing them to bulge painfully from their sockets, as in the late actor Marty Feldman.

1 Mar 2007

Key protein - claudin-1- for hepatitis C virus entry identified

For as many as 200 million people worldwide infected with hepatitis C, a leading cause of chronic liver disease, treatment options are only partially effective. But new research by Rockefeller University scientists points to a potential new target for better drugs: a key protein that resides in human liver cells that hepatitis C requires for entry.

27 Feb 2007

Quantum rods and dots image cancer cells

Brightly fluorescent quantum dots and quantum rods are quickly becoming important tools for identifying specific molecules and cells in living systems. Two new reports demonstrate some of the ways in which cancer researchers are using these nanoscale imaging agents.

26 Feb 2007

Imaging of disease dynamics during meningococcal sepsis

Each year 170,000 people around the world die of this type of meningitis, according to the World Health Organization, (WHO).

21 Feb 2007

Health care professionals should focus on women's lifetime heart disease risk

The 2007 Guidelines for Preventing Cardiovascular Disease in Women -- published today in a special women's health issue of Circulation: Journal of the American Heart Association -- also include new directions for using aspirin, hormone therapy and vitamin and mineral supplements in heart disease and stroke prevention in women.

20 Feb 2007

Tamoxifen offers long-term benefits for breast cancer prevention among women at high risk

The trials found that the breast cancer risk reduction persists long after women stop taking tamoxifen.

20 Feb 2007

Low levels of RANTES protein in the blood is a predictor of cardiac death

Researchers at SUNY Downstate Medical Center in Brooklyn have determined that low levels of a protein in the blood is a predictor of cardiac death in patients with coronary artery disease.

20 Feb 2007

Researchers discover markers that identify breast cancer subtypes resistant to Herceptin

Using gene chips to profile tumors before treatment, researchers at Harvard and Yale Universities found markers that identified breast cancer subtypes resistant to Herceptin, the primary treatment for HER2-positive breast cancer. They say this advance could help further refine therapy for the 25 to 30 percent of breast cancer patients with this class of tumor.

20 Feb 2007

siRNA delivery into human T cells and primary cells with carbon-nanotube transporters

A promising approach to gene therapy involves short DNA fragments (interfering RNA) that bind to specific genes and block their "translation" into the corresponding, disease-related protein.

20 Feb 2007

Beta-blockers should not be a doctor's first choice for treating high blood pressure

Beta-blocker drugs such as Tenormin, Inderal and Lopressor should not be a doctor's first choice for treating high blood pressure, according to a large new review of studies.

20 Feb 2007

How T cells attack tumors

Our immune system struggles to eliminate tumors effectively. By unraveling its strategies, we can enhance its effects on tumor cells and so improve the clinical prospects of cancer immunotherapy.

20 Feb 2007

Nanoparticles rely on 'velcro effect' to target tumor cells

One of the basic tenets of targeted nanoparticle drug delivery is putting multiple targeting molecules on a nanoparticle surface will improve the ability of nanoparticles to stick to their targeted cell and deliver their drug cargos to the appropriate diseased cell.

20 Feb 2007

An aspirin a day keeps heart disease away

According to new guidelines released by the American Heart Association, almost all women are at risk of heart disease and doctors should consider prescribing a daily aspirin for them.

20 Feb 2007

Updated guidelines provide definitive answers on HRT, aspirin, supplements

Health care professionals should focus on women's lifetime heart disease risk, not just short-term risk, according to updated American Heart Association guidelines.

20 Feb 2007

Cell pathway identified which plays critical role in colon cancer

For the one in 18 men and women who will be diagnosed with cancer of the colon and rectum during their lifetime and over 150,000 people diagnosed on a yearly basis, today's genetic research news offers some optimism.

20 Feb 2007

More evidence that inflammation can fuel cancer

As evidence mounts that the body's normally protective inflammation response can drive some precancerous tissues to become fully malignant, UCSF scientists report discovering an apparent trigger to this potentially deadly process.

19 Feb 2007

Genetic variations contribute to a person's risk for nicotine dependence

Americans are bombarded with antismoking messages, yet at least 65 million of us continue to light up. Genetic factors play an important role in this continuing addiction to cigarettes, suggest scientists at Washington University School of Medicine in St. Louis.

18 Feb 2007