Antibodies News and Research

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Novel delivery system selectively delivers antibiotics to specific targets

Physicists at McMaster University have identified a natural delivery system which can safely carry potent antibiotics throughout the body to selectively attack and kill bacteria by using red blood cells as a vehicle.

1 Nov 2022

Monoclonal antibody shows efficacy in preventing malaria infection in African adults

One dose of an antibody drug safely protected healthy, non-pregnant adults from malaria infection during an intense six-month malaria season in Mali, Africa, a National Institutes of Health clinical trial has found.

31 Oct 2022

New system to detect cancer-related markers on CTCs

Having biopsies taken and endless tests run is nobody's idea of a good time, even if it's necessary for monitoring your health.

31 Oct 2022

New research suggests booster dose of Novavax NVX-CoV2373 vaccine is effective against SARS-CoV-2 Omicron subvariants

A new study evaluated the neutralizing antibody titers against the SARS-CoV-2 Omicron variant and its sub-lineages after two and three doses of the Novavax protein nanoparticle vaccine NVX-CoV2373.

31 Oct 2022

What is the impact of SARS-CoV-2 on HIV-1 infectivity?

In a new study, researchers assessed the effect of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and SARS-CoV envelope (E) proteins on human immunodeficiency virus type 1 (HIV-1) infectivity.

31 Oct 2022

SpyCatcher-SpyTag technology used to develop recombinant protein-based intranasal vaccine against SARS-CoV-2

The findings of a new study showed that the intranasal SpyCage vaccine platform can be protective against SARS-CoV-2 and may prove to be a versatile and adaptable modality for the formulation of intranasal vaccines that target respiratory pathogens.

31 Oct 2022

An innovative nasal vaccine strategy to combat COVID

In a recent study published in the journal Science, researchers at Yale University developed a novel coronavirus disease 2019 (COVID-19) vaccination strategy termed 'prime and spike' (P&S) that leveraged existing systemic immunity triggered by parenteral vaccination (prime) to boost immunity at the respiratory mucosa.

31 Oct 2022

SARS-CoV-2 infection can affect menstruation

Researchers assess the association between SARS-CoV-2 infection and menstrual irregularities.

30 Oct 2022

Study reports on a novel property of antibodies, light chain coherence

Researchers investigate whether pairs of unrelated B-cells that have similar heavy chains also have the same light chains.

30 Oct 2022

Favorable outcomes of infants born after maternal COVID-19 during pregnancy

Researchers assess the outcomes of children born to mothers infected during pregnancy with SARS-CoV-2.

30 Oct 2022

New insights on antibody response against SARS-CoV-2 Omiron sublineages

Knowing how well vaccination against one SARS-CoV-2 strain (with or without previous infection) counteracts infection with a different strain is a critical research question.

28 Oct 2022

First anti-SARS Cov2 monoclonal antibody candidate of SpikImm demonstrates excellent tolerance

SPK001, the first anti-SARS Cov2 monoclonal antibody candidate of SpikImm, a French biotechnology company founded by Truffle Capital, originally discovered by the Institut Pasteur's Human Immunology Laboratory, directed by Dr. Hugo Mouquet (Inserm Joint Research Unit), has been tested on three initial cohorts of healthy volunteers, and has demonstrated excellent tolerance, in the context of the Phase 1 clinical study, recently labeled as a "national priority" by CAPNET (National Steering Committee for Therapeutic Trials and other Research on Covid-19).

28 Oct 2022

Research shows in real time how immune memory cells are stored in the bone marrow

Vaccines work their magic by effectively creating immune cells that are long lived, often for over decades.

28 Oct 2022

Research reveals a differential clinical response to pembrolizumab in uterine cancer patients

New research from Yale Cancer Center reveals for the first time ever a differential clinical response to pembrolizumab in Lynch-like (mutated) vs methylated microsatellite instability-high (MSI-H) uterine cancer patients, increasing our understanding about the proportion of patients that derive benefit from immune checkpoint blockade.

28 Oct 2022

Scientists computationally restore the potency of an antibody against SARS-CoV-2 Omicron subvariants

A team of researchers from the United States computationally modified the COV2-2130 monoclonal antibody to restore its neutralizing ability against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron subvariants, while retaining efficacy against the Delta and wild-type strains.

27 Oct 2022

Combination of multi-specificity and antibody avidity enhances protection against SARS-CoV-2

In a recent study posted to the bioRxiv* preprint server, an international team of researchers leveraged the human light chain apoferritin protomer-derived MULTI-specific, multi-Affinity antibody (Multabody, MB) platform for the generation of broad and potent SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2)-neutralizing antibodies (Abs).

27 Oct 2022

Rutgers physicians take newer approach in successfully treating a mysterious disease

The prognosis for the sick child, who hadn't responded to standard treatment, was dire. But a team of Rutgers physicians believed there might be hope despite the conventional wisdom against pursuing any further treatment.

27 Oct 2022

Updapted BA.4/5 COVID vaccines boost protection but might not surpass original formula

In a recent study posted to the bioRxiv* preprint server, researchers at Beth Israel Deaconess Medical Center assessed the immunogenicity associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) BA.5 bivalent messenger ribonucleic acid (mRNA) vaccine boosters.

27 Oct 2022

Study shows the potential of experimental monoclonal antibodies to treat Epstein-Barr virus infection

A panel of investigational monoclonal antibodies (mAbs) targeting different sites of the Epstein-Barr virus (EBV) blocked infection when tested in human cells in a laboratory setting.

27 Oct 2022

Study elucidates mechanism that is crucial for making hemophilia therapy effective

Hemophilia A is the most common severe form of hemophilia. It affects almost exclusively males. The disease can usually be treated well, but not for all sufferers.

27 Oct 2022

Antibodies News and Research

Novel delivery system selectively delivers antibiotics to specific targets

Monoclonal antibody shows efficacy in preventing malaria infection in African adults

New system to detect cancer-related markers on CTCs

New research suggests booster dose of Novavax NVX-CoV2373 vaccine is effective against SARS-CoV-2 Omicron subvariants

What is the impact of SARS-CoV-2 on HIV-1 infectivity?

SpyCatcher-SpyTag technology used to develop recombinant protein-based intranasal vaccine against SARS-CoV-2

An innovative nasal vaccine strategy to combat COVID

SARS-CoV-2 infection can affect menstruation

Study reports on a novel property of antibodies, light chain coherence

Favorable outcomes of infants born after maternal COVID-19 during pregnancy

New insights on antibody response against SARS-CoV-2 Omiron sublineages

First anti-SARS Cov2 monoclonal antibody candidate of SpikImm demonstrates excellent tolerance

Research shows in real time how immune memory cells are stored in the bone marrow

Research reveals a differential clinical response to pembrolizumab in uterine cancer patients

Scientists computationally restore the potency of an antibody against SARS-CoV-2 Omicron subvariants

Combination of multi-specificity and antibody avidity enhances protection against SARS-CoV-2

Rutgers physicians take newer approach in successfully treating a mysterious disease

Updapted BA.4/5 COVID vaccines boost protection but might not surpass original formula

Study shows the potential of experimental monoclonal antibodies to treat Epstein-Barr virus infection

Study elucidates mechanism that is crucial for making hemophilia therapy effective

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