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Antifibrotic effect of hepatocyte growth factor is impaired in lung fibroblasts isolated from African-Americans

Of the more than 40,000 persons who die each year in the U.S. from pulmonary fibrosis, the mortality rate among African-Americans is twice as high Caucasians.

11 Apr 2006

Researchers engineer cells in the eye to be light sensitive that were not before

In an experiment that could offer a new pathway to restoring vision in people with inherited retinal degeneration, researchers have engineered cells in the eye to be light sensitive that were not before.

11 Apr 2006

Fish oil may help protect against age-related macular degeneration

A paper published in Trends in Neuroscience by Nicolas G. Bazan, MD, PhD of the Neuroscience Center of Excellence at LSU Health Sciences Center in New Orleans, reports on the role that the omega-3 fatty acids in fish oil play in protecting cells in the retina from degenerative diseases like retinitis pigmentosa and age-related macular degeneration.

7 Apr 2006

Starvation activates MAP Kinase through the muscarinic acetylcholine pathway in Caenorhabditis elegans pharynx

New evidence in Cell Metabolism reveals a molecular mechanism that may play a general role in animals' ability to respond appropriately when starved.

7 Apr 2006

Caenorhabditis elegans helps unravel mechanisms of hunger

In research that may have implications for studying eating disorders in humans, a worm the size of a pinhead is helping researchers at UT Southwestern Medical Center unravel the mechanisms of hunger.

6 Apr 2006

Ingredient in red peppers inhibits prostate cancer in laboratory studies

Capsaicin is the pungent ingredient in red peppers and is presently used as a topical pain reliever. Now, a new study shows it may be justified to evaluate capsaicin for inhibiting prostate cancer (CaP) in patients.

5 Apr 2006

Prostate drug doxazosin blocks receptor in heart muscle, increasing risk of heart failure

Doxazosin, a drug commonly prescribed to help improve urinary flow in men with enlarged prostates, increases the likelihood of heart failure by blocking specific receptors in heart muscle cells, according to a study conducted at the San Francisco VA Medical Center.

4 Apr 2006

Panitumumab shows promise for patients with colorectal cancer

Results from a Phase III study of a new drug show promise for patients with colorectal cancer that has spread to other parts of the body, according to a study presented during the 97th Annual Meeting of the American Association for Cancer Research.

4 Apr 2006

Promising new targets for Alzheimer's drug therapies

An enzyme previously associated with preventing the dementia of Alzheimer's disease now appears to play an even bigger role in safeguarding against the disease, bringing the promise of new targets for drug therapies.

4 Apr 2006

HOXB13 and IL17BR genes predict outcome for breast cancer patients

The 2-gene expression profile of HOXB13 and IL17BR in a woman's breast cancer predicts risk of recurrence in node-negative patients treated with tamoxifen.

4 Apr 2006

Mayo Clinic discover cellular secret that may explain how certain cancers move and spread

If the mechanism that drives cancer movement - also called metastasis - can be understood well enough to manipulate it, new and better treatments can be developed for patients with metastatic cancers.

4 Apr 2006

Targeting the inflamed synovium: The quest for specificity

In the April 2006 issue of Arthritis & Rheumatism, noted rheumatology specialists with Kings College London, Dr. Toby Garrood and Dr. Costantino Pitzalis offer an overview of recent breakthroughs and a preview of future directions in this critical quest for specificity.

4 Apr 2006

Couch potato? no just motivational deficiency disordered!

According to Australian scientists, being a couch potato may actually be an illness.

3 Apr 2006

Discovery of a gene that drives anthrax bacteria's toxic effects

A study in Cell reports the discovery of a gene that drives anthrax bacteria's toxic effects. The gene could offer a potential new target for countermeasures against the lethal toxin, according to the researchers.

28 Mar 2006

Mustard and garlic kick linked to single pain receptor

A single pain receptor is solely responsible for the kick delivered by mustard oil and garlic, according to research in the Cell. Mustard oil is the active ingredient in mustard and in the pungent green sushi condiment known as wasabi.

28 Mar 2006

Study investigates how age relates to survival outcome in patients with early stage breast cancer

A 30 year old woman diagnosed with breast cancer has the same chance of survival as a 60 year old woman with breast cancer according to the latest findings presented at the European Breast Cancer Conference (EBCC-5).

23 Mar 2006

Long term reduction in LDL cholesterol dramatically reduces risk of heart disease

A new genetic analysis of more than 12,000 individuals has found that a decrease in low density lipoprotein (LDL) cholesterol, of as little as 15 percent, sustained over the long term can dramatically reduce the risk of coronary heart disease.

23 Mar 2006

Raloxifene shows potential benefits in treating prostate cancer

In a study to be published in the April, 2006 issue of the British Journal of Urology International, researchers at Cedars-Sinai Medical Center have shown that Raloxifene, a drug commonly used to treat osteoporosis, has a potential clinical benefit in treating men with prostate cancer.

23 Mar 2006

Divergent behavioral roles of angiotensin receptor intracellular signaling cascades

Researchers at the University at Buffalo and the University of Pennsylvania were the first to demonstrate that two intracellular events, both stimulated by the same cell receptor, can provoke different behaviors in mammals.

23 Mar 2006

Study shows that cell transplantation therapy may improve brain receptor function in patients who suffered from cerebral stroke

Japanese researchers have found a piece of the "missing link" about how bone marrow stromal cells restore lost neurologic function when transplanted into animals exhibiting central nervous system disorders, according to a study in the March issue of the Journal of Nuclear Medicine.

21 Mar 2006

Receptor News and Research

Antifibrotic effect of hepatocyte growth factor is impaired in lung fibroblasts isolated from African-Americans

Researchers engineer cells in the eye to be light sensitive that were not before

Fish oil may help protect against age-related macular degeneration

Starvation activates MAP Kinase through the muscarinic acetylcholine pathway in Caenorhabditis elegans pharynx

Caenorhabditis elegans helps unravel mechanisms of hunger

Ingredient in red peppers inhibits prostate cancer in laboratory studies

Prostate drug doxazosin blocks receptor in heart muscle, increasing risk of heart failure

Panitumumab shows promise for patients with colorectal cancer

Promising new targets for Alzheimer's drug therapies

HOXB13 and IL17BR genes predict outcome for breast cancer patients

Mayo Clinic discover cellular secret that may explain how certain cancers move and spread

Targeting the inflamed synovium: The quest for specificity

Couch potato? no just motivational deficiency disordered!

Discovery of a gene that drives anthrax bacteria's toxic effects

Mustard and garlic kick linked to single pain receptor

Study investigates how age relates to survival outcome in patients with early stage breast cancer

Long term reduction in LDL cholesterol dramatically reduces risk of heart disease

Raloxifene shows potential benefits in treating prostate cancer

Divergent behavioral roles of angiotensin receptor intracellular signaling cascades

Study shows that cell transplantation therapy may improve brain receptor function in patients who suffered from cerebral stroke

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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