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A newly recognized type of immune cell may play an important role in causing asthma

...perhaps explaining why current therapies sometimes fail, report researchers from Children's Hospital Boston in the New England Journal of Medicine.

21 Mar 2006

Emergence of a human-adapted H5 virus is a clear threat to public health worldwide

The H5N1 avian influenza virus, commonly known as "bird flu," is a highly contagious and deadly disease in poultry. So far, its spread to humans has been limited, with 177 documented severe infections, and nearly 100 deaths in Indonesia, Vietnam, Thailand, Cambodia, China, Iraq, and Turkey as of March 14, 2006, according to the World Health Organization.

21 Mar 2006

New research suggests it may be possible to separate the anticancer properties of vitamin D

At the right dose, vitamin D is important for bone development and may help protect against the development of several cancers, particularly colorectal cancer.

21 Mar 2006

Researcher identifies the cellular receptor for botulinum neurotoxin A

Botulinum neurotoxin A can be either the greatest wrinkle remover or one of the world's most potent biological weapons. To perform either job, however, the toxin must first find a way to enter cells.

20 Mar 2006

H5N1 influenza virus is undergoing genetic diversity expansion

An analysis of H5N1 influenza samples in Southeast Asia shows not only how the two strains that have caused human disease are related but also that they belong to two different, distinct genetic subgroups.

20 Mar 2006

Hypertension reduced with early intervention

Treating pre-hypertension with medication and lifestyle modifications reduces the risk of patients progressing to hypertension, a new study involving researchers at UT Southwestern Medical Center has concluded.

19 Mar 2006

Study offers piece of missing link needed in understanding receptor function possibly providing safe, ethical source for replacing brain cells

Japanese researchers have found a piece of the "missing link" about how bone marrow stromal cells restore lost neurologic function when transplanted into animals exhibiting central nervous system disorders, according to a study in the March issue of the Journal of Nuclear Medicine.

19 Mar 2006

Link between genetic variation and outcome of antidepressant treatment

Whether depressed patients will respond to an antidepressant depends, in part, on which version of a gene they inherit, a study led by scientists at the National Institutes of Health (NIH) has discovered.

15 Mar 2006

Researchers evaluate efficacy, safety of anti-clotting drugs

Patients admitted to the hospital with an acute coronary syndrome (ACS) are often treated with a catheter-based procedure known as percutaneous coronary intervention, or PCI.

15 Mar 2006

Profound alterations in the brain mechanisms that regulate motivated behavior with addiction

Rats that have a strong craving for cocaine have a different biochemical response to the drug than their less-addicted counterparts, researchers at UT Southwestern Medical Center have found.

15 Mar 2006

Capsaicin drives prostate cancer cells to kill themselves

Capsaicin, the stuff that turns up the heat in jalapeqos, not only causes the tongue to burn, it also drives prostate cancer cells to kill themselves, according to studies published in the March 15 issue of Cancer Research.

15 Mar 2006

Hormone C-type natriuretic peptide protects the heart muscle from thickening abnormally

When the heart is weakened, it tries to compensate for its impaired pumping function through an enlargement of the heart muscle cells. Physicians speak in this case of cardiac hypertrophy, abnormal enlargement of the heart.

13 Mar 2006

Aspirin still the best for reducing the heart attack risk

New research has revealed that the addition of the blood-thinning drug Plavix to a daily dose of aspirin does not lower the risk of death, heart attack or stroke in high-risk patients.

13 Mar 2006

Study reveals mechanisms behind Thiazolidinediones used to treat type 2 diabetes

Thiazolidinediones (TZD's) are drugs commonly prescribed to patients with type 2 diabetes, the most common form of diabetes. Current U.S. Food and Drug Administration-approved agents are known as Actos (pioglitazone) and Avandia (rosiglitazone).

13 Mar 2006

Scientists exploit novel route to reverse enlarged hearts in obese mice

Working on genetically engineered obese mice with seriously thickened hearts, a condition call cardiac hypertrophy, scientists at Johns Hopkins have used a nerve protection and growth factor on the heart to mimic the activity of the brain hormone leptin, dramatically reducing the size of the heart muscle.

13 Mar 2006

Smk-1 is the first known gene that regulates longevity without disrupting life-sustaining function

Within a hormone-triggered cascade of molecular signals that plays a crucial for a wide range of physiological functions, researchers for the very first time have identified a protein that functions specifically to extend lifespan and youthfulness - without disrupting fertility

13 Mar 2006

New approach to preventing recurrent febrile seizures in vulnerable children

It's one of those unavoidable facts of life - kids get sick and have fevers. Usually, those elevated internal temperatures cause only temporary discomfort, but in some small children they spark convulsions called "febrile seizures."

13 Mar 2006

New AF267B drug reverses key cognitive deficits, pathology in Alzheimer's

A new drug that enhances the activity of a key brain cell receptor involved in Alzheimer's disease (AD) reverses learning and memory deficits in mice engineered to have pathological hallmarks of the disease.

13 Mar 2006

Stroke researchers have traced the major cause of the death of brain cells

In the neurological train wreck that is stroke, researchers have traced the major cause of the death of brain cells due to artery blockage or bleeding in the brain.

13 Mar 2006

A map of recent positive selection in the human genome

By scanning the entire human genome in search of genetic variations that may signal recent evolution, University of Chicago researchers found more than 700 genetic variants that may be targets of recent natural positive selection during the past 10,000 years of human evolution.

13 Mar 2006

Receptor News and Research

A newly recognized type of immune cell may play an important role in causing asthma

Emergence of a human-adapted H5 virus is a clear threat to public health worldwide

New research suggests it may be possible to separate the anticancer properties of vitamin D

Researcher identifies the cellular receptor for botulinum neurotoxin A

H5N1 influenza virus is undergoing genetic diversity expansion

Hypertension reduced with early intervention

Study offers piece of missing link needed in understanding receptor function possibly providing safe, ethical source for replacing brain cells

Link between genetic variation and outcome of antidepressant treatment

Researchers evaluate efficacy, safety of anti-clotting drugs

Profound alterations in the brain mechanisms that regulate motivated behavior with addiction

Capsaicin drives prostate cancer cells to kill themselves

Hormone C-type natriuretic peptide protects the heart muscle from thickening abnormally

Aspirin still the best for reducing the heart attack risk

Study reveals mechanisms behind Thiazolidinediones used to treat type 2 diabetes

Scientists exploit novel route to reverse enlarged hearts in obese mice

Smk-1 is the first known gene that regulates longevity without disrupting life-sustaining function

New approach to preventing recurrent febrile seizures in vulnerable children

New AF267B drug reverses key cognitive deficits, pathology in Alzheimer's

Stroke researchers have traced the major cause of the death of brain cells

A map of recent positive selection in the human genome

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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