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Genes affect how asthma patients respond to albuterol

While a few weeks of regular use of albuterol improved overall asthma control in individuals with one form of the gene, stopping all use of albuterol eventually improved asthma control in those with another form of the gene. Albuterol is the most commonly used drug for relief of acute asthma symptoms, or “attacks.”

22 Oct 2004

Research opens new possibilities for the treatment of metabolic disorders such as diabetes and obesity

For the first time, researchers from the Flanders Interuniversity Institute for Biotechnology (VIB) connected with the Catholic University of Leuven have shown clearly that receptors in yeast cells detect and react to nutrients in the cell.

21 Oct 2004

Highly sensitive receptors in the brain may function differently in a person with a family history of alcoholism

Receptors in the brain that are highly sensitive to alcohol may function differently in a person with a family history of alcoholism, according to a Yale study published this month.

21 Oct 2004

Researchers have uncovered a specific signaling mechanism that contributes to the development of colorectal cancer

The discovery furthers the understanding of mechanisms that contribute to disease progression and provides new avenues for development of therapies for colorectal cancer.

21 Oct 2004

Genetic predictions may bring “quantum leap” in breast cancer treatment success

Researchers at Virginia Commonwealth University’s Massey Cancer Center received a prestigious award and a $600,000 grant from the V Foundation for Cancer Research, one of the nation’s leading organizations devoted exclusively to funding cancer research.

20 Oct 2004

Possible link between elevated calcium levels in older neurons and aging-related disorders of the brain

Brain cells become increasingly unable to regulate calcium loads as they age, becoming more vulnerable to injury and premature death, according to new findings that Virginia Commonwealth University researchers will present at an international conference this month.

20 Oct 2004

Brain protein called MC4R that plays a role in the urge to eat has now been found to influence appetite in a second way

A brain protein already known to play a central role in the "feast or fast" signaling that controls the urge to eat has now been found to influence appetite in a second way. The discovery identifies a potential new target for drugs against obesity.

19 Oct 2004

Investigational drug for pulmonary hypertension may improve the quality of life for patients with scleroderma and lupus

An investigational new drug for pulmonary hypertension may improve the quality of life for thousands of patients with scleroderma, lupus, and other associated connective tissue diseases, according to research presented this week at the American College of Rheumatology Annual Scientific Meeting in San Antonio, Texas.

18 Oct 2004

Collaborative research will help bring hope to Americans who are losing their sight to degenerative retinal diseases

A collaborative research and development agreement signed today between the U.S. Department of Energy (DOE) and Second Sight LLC will help bring hope to hundreds of thousands of Americans who are losing their sight to degenerative retinal diseases.

18 Oct 2004

New treatment antibody - AMG 162 - may help prevent osteoporosis and rheumatoid arthritis

A novel treatment administered semiannually to postmenopausal women with low bone density appears to rapidly inhibit the bone resorption process, resulting in improvements in bone mineral density at 12 months

18 Oct 2004

Highly concentrated solution of chemical messengers could block male to female HIV transmission

Researchers in the U.S have shown that it may be possible to block the transmission of the HIV virus from a man to a woman by using a highly concentrated solution of chemical messengers that attract white blood cells to the site of infection.

16 Oct 2004

Researchers identify common mutation in T-cell acute lymphocytic leukemia

Researchers at Brigham and Women’s Hospital (BWH) and Dana-Farber Cancer Institute (DFCI) have made a breakthrough discovery, identifying a common mutation in T-cell acute lymphocytic leukemia (T-ALL), an important form of cancer in children and adolescents.

11 Oct 2004

Genetic link to Preeclampsia, a serious complication of pregnancy

When a particular combination of proteins is expressed by a mother and her developing fetus, the risk of developing preeclampsia increases, according to a study by Hiby and colleagues in the Oct 18 issue of The Journal of Experimental Medicine.

11 Oct 2004

Research has identified Dectin-1 as the beta-glucan receptor on immune cells

This finding may be of use in the prophylactic prevention of a variety of infections, especially in surgical patients, and in the treatment of cancer. The identification of Dectin-1 as the beta-glucan receptor may also provide a novel strategy for combating fungal infections.

10 Oct 2004

Research shows C. botulinum uses SONO to detect nitric oxide

A deadly bacterium's defense against a mortal molecular enemy illuminates the origins and structure of a vital protein involved in human cell signaling, University of Texas Medical School scientists report in Science Express.

8 Oct 2004

Cocaine addicts experience a decrease in D2 receptors affecting brain regions involved with movement, as well as motivation

A new study builds on previous research showing that cocaine-addicted people have a low expression of specific dopamine receptors—D2 receptors—in a portion of the brain called the striatum.

6 Oct 2004

Richard Axel has won the 2004 Nobel Prize in physiology or medicine

Richard Axel of the Columbia University Medical Center has won the 2004 Nobel Prize in Physiology or Medicine along with Linda B. Buck of the Fred Hutchinson Cancer Research Center for clarifying how the olfactory system works.

5 Oct 2004

Linda Buck has been named winner of the 2004 Nobel Prize in physiology or medicine

Linda Buck, Ph.D., a member of Fred Hutchinson Cancer Research Center's Basic Sciences Division, has been named winner of the 2004 Nobel Prize in physiology or medicine.

5 Oct 2004

New technique offers efficient blood cleansing

Blood poisoning is fatal in almost half of all cases. Patients could be helped by efficient blood cleansing. Scientists are working on a new technique that will quickly and effectively retrieve toxic substances from the vital fluid without altering the blood count.

4 Oct 2004

High blood pressure can effect many life activities, including sex

Despite its seeming invisibility, high blood pressure is dangerous, even deadly. Its effects can linger throughout many life activities, including sex.

29 Sep 2004

Receptor News and Research

Genes affect how asthma patients respond to albuterol

Research opens new possibilities for the treatment of metabolic disorders such as diabetes and obesity

Highly sensitive receptors in the brain may function differently in a person with a family history of alcoholism

Researchers have uncovered a specific signaling mechanism that contributes to the development of colorectal cancer

Genetic predictions may bring “quantum leap” in breast cancer treatment success

Possible link between elevated calcium levels in older neurons and aging-related disorders of the brain

Brain protein called MC4R that plays a role in the urge to eat has now been found to influence appetite in a second way

Investigational drug for pulmonary hypertension may improve the quality of life for patients with scleroderma and lupus

Collaborative research will help bring hope to Americans who are losing their sight to degenerative retinal diseases

New treatment antibody - AMG 162 - may help prevent osteoporosis and rheumatoid arthritis

Highly concentrated solution of chemical messengers could block male to female HIV transmission

Researchers identify common mutation in T-cell acute lymphocytic leukemia

Genetic link to Preeclampsia, a serious complication of pregnancy

Research has identified Dectin-1 as the beta-glucan receptor on immune cells

Research shows C. botulinum uses SONO to detect nitric oxide

Cocaine addicts experience a decrease in D2 receptors affecting brain regions involved with movement, as well as motivation

Richard Axel has won the 2004 Nobel Prize in physiology or medicine

Linda Buck has been named winner of the 2004 Nobel Prize in physiology or medicine

New technique offers efficient blood cleansing

High blood pressure can effect many life activities, including sex

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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