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Industrial chemical perfluorobutanoic acid less likely to accumulate in human lungs and kidneys

A 2013 study by Pérez et al. reported a very high accumulation of the industrial chemical perfluorobutanoic acid (PFBA) in human lungs and kidneys. The German Federal Institute for Risk Assessment (BfR) checked these results using a more precise quantification method. The result: Only one sample contained a quantifiable PFBA value of 0.17 nanograms (ng) per gram (g) of lung tissue.

25 Sep 2021

May-Thurner anatomy common in patients with CTEPH, new study shows

Like highways, roads, and side streets, blood vessels in the human body come in different sizes, with a range of traffic-carrying capacities. These differences are critical to facilitating blood flow through tissues.

24 Sep 2021

Mathematical constructions of SARS-CoV-2 action could help fine-tune prevention and treatment

Mathematical constructions of the action of SARS-CoV-2 and its multiple spikes, which enable its success at infecting cells, can give vaccine developers and pharmaceutical companies alike a more precise picture of what the virus is doing inside us and help fine tune prevention and treatment, mathematical modelers say.

23 Sep 2021

How SARS-CoV-2 spike binds to multiple host receptors

Researchers from the Genos Glycoscience Research Laboratory in Croatia have recently investigated the sites that the S protein is capable of binding with.

23 Sep 2021

Hypertonic saline solution shown to inhibit replication of SARS-CoV-2

Researchers at the University of São Paulo (USP) in Brazil have shown that a hypertonic saline solution inhibits replication of SARS-CoV-2, the virus that causes COVID-19, and have elucidated the biochemical mechanism involved.

22 Sep 2021

Unique tiny Ilamas antibodies could be used for treatment of COVID-19

A unique type of tiny antibody produced by llamas could provide a new frontline treatment against Covid-19 that can be taken by patients as a simple nasal spray.

22 Sep 2021

At an overrun ICU, ‘the problem is we are running out of hallways’

Nurses fill the hospital room to turn a patient from his stomach to his back. The ventilator forcing air into him is most effective when he's on his stomach, so he is in that position most hours of the day, sedated and paralyzed by drugs.

22 Sep 2021

Signs and risk factors of pulmonary embolism missed in dementia patients

Patients with dementia who had signs and risk factors of a pulmonary embolism, or a blood clot in the lungs, were much less likely to be tested for pulmonary embolism than patients without dementia who had the same signs and risk factors.

21 Sep 2021

California’s reboot of troubled Medi-Cal puts pressure on health plans

When Denise Williams' baby boy was 2 months old, she became alarmed by a rattling sound in his lungs and took him to the emergency room. While undergoing treatment, he spiraled into a disabling neurological disorder.

21 Sep 2021

Dynamics of innate immune responses decide COVID-19 severity in genetically diverse mice

In a recently published article on the bioRxiv* preprint server, scientists from the USA and UK have described the significance of early inflammatory signaling pathways in determining the severity of coronavirus disease 2019 (COVID-19).

21 Sep 2021

Changes in fibrin clot structure contributes to thrombosis risk in severe COVID-19

Researchers from Europe recently demonstrated altered levels of factor XII (FXII) and its activation products in 2 independent cohorts of critically ill patients with COVID-19 compared to patients suffering from severe acute respiratory distress syndrome caused by the influenza virus (acute respiratory distress syndrome (ARDS)-influenza).

21 Sep 2021

Research could lead to new treatment option for breast cancer patients with brain metastases

Breast cancer patients whose cancer spreads to the brain may soon have new treatment options, thanks to research led by CU Cancer Center member Diana Cittelly, PhD.

21 Sep 2021

Study uncovers a new way to counter immune suppression in tumors

Malignant tumors can enhance their ability to survive and spread by suppressing antitumor immune cells in their vicinity, but a study led by researchers at Weill Cornell Medicine and NewYork-Presbyterian has uncovered a new way to counter this immunosuppressive effect.

20 Sep 2021