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UofL receives DoD funding to develop a nasal spray for preventing COVID-19

The University of Louisville has received funding from the U.S. Department of Defense (DoD) to develop a nasal spray to prevent serious viral respiratory infections such as COVID-19 using Q-Griffithsin, a drug compound developed and co-owned by UofL.

9 Dec 2020

WHO highlights leading causes of mortality and morbidity worldwide from 2000 to 2019

Noncommunicable diseases now make up 7 of the world's top 10 causes of death, according to WHO's 2019 Global Health Estimates, published today.

9 Dec 2020

HIV/AIDS testing and treatment can be adapted to achieve similar interventions to mitigate COVID-19

A research project is exploring whether interventions that have been effective at engaging high-risk populations in HIV/AIDS testing and treatment can be adapted to achieve similar effects in mitigating COVID-19.

9 Dec 2020

Scientists identify two drug candidates that counteract deficiencies caused by lack of MECP2 gene

Most autism spectrum disorders have a complex, multifactorial genetic component, making it difficult to find specific treatments. Rett syndrome is an exception.

9 Dec 2020

People with Bartonella infection exhibit neuropsychiatric symptoms, skin lesions

Bartonella bacteria are increasingly recognized as an emerging infectious disease threat. A new study by North Carolina State University researchers has found additional instances of Bartonella infection in humans who exhibited neuropsychiatric symptoms, a subset of whom also had skin lesions.

8 Dec 2020

Clinical investigators present abstracts on hematological malignancies at ASH Annual Meeting and Exposition

Clinical investigators from Hackensack Meridian Health John Theurer Cancer Center (JTCC), a member of the Georgetown Lombardi Comprehensive Cancer Center consortium, are to present updates on treatment advances in multiple myeloma (MM), mantle cell lymphoma (MCL), and other types of B-cell lymphoma (BCL) as well as leukemia at the 62nd American Society of Hematology (ASH) Annual Meeting and Exposition, to be held virtually from December 5-8, 2020.

7 Dec 2020

CRISPR-based test could provide rapid, low-cost testing to help control COVID-19 spread

Imagine swabbing your nostrils, putting the swab in a device, and getting a read-out on your phone in 15 to 30 minutes that tells you if you are infected with the COVID-19 virus.

5 Dec 2020

The vaginal microbiome may impact the efficacy of HIV prevention therapy

A new study has revealed that vaginal microbial communities are linked with an increased risk of HIV acquisition and may also impact the efficacy of PrEP.

3 Dec 2020

Despite new CDC guidance, opioid prescription rates have not declined

Research from Saint Louis University finds that among patients at risk for opioid misuse, the odds of receiving a schedule II opioid for non-cancer pain were similar to those not at risk, despite new prescribing guidelines from the Centers for Disease Control (CDC).

2 Dec 2020

Global solidarity, resilient services to reduce TB deaths among people living with HIV

The theme of this year's World AIDS Day is "Global solidarity, resilient services". At the 2016 UN High-level Meeting on ending AIDS, member states committed to a 75% reduction of TB deaths among people living with HIV by 2020, compared with 2010.

2 Dec 2020

Pharmacophore model helps find key protease inhibitor responsible for COVID-19

A team of San Diego Supercomputer Center (SDSC) researchers recently created a pharmacophore model and conducted data mining of the database of drugs approved by the U.S. Federal Drug Administration (FDA) to find potential inhibitors of papain-like protease of SARS-CoV2, one of the main viral proteins responsible for COVID-19.

2 Dec 2020

New research project to develop and test novel intervention for individuals with HIV/AIDS

Tulsa CARES is partnering with researchers at the Hudson College of Public Health at the University of Oklahoma Health Sciences Center and the OU-TU School of Community Medicine at the University of Oklahoma to develop and test a novel "food as medicine" intervention for individuals affected by HIV/AIDS.

2 Dec 2020

HIV 'wonder drug' may not be as effective as hoped in sub-Saharan Africa, study suggests

Dolutegravir, the current first-line treatment for HIV, may not be as effective as hoped in sub-Saharan Africa, suggests new research published on World AIDS Day. The study finds that this so-called 'wonder drug' may be less effective in patients resistant to older drugs.

1 Dec 2020

Potential SARS-CoV-2 antiviral: Ionophore X-206 found to inhibit viral replication in cell cultures

In a study published in the journal Antiviral Research, researchers from Aarhus University, Denmark, report on their tests on different polyether ionophores to inhibit SARS-CoV-2 in vitro.

1 Dec 2020

Where COVID is on the menu: Failed contact tracing leaves diners in the dark

COVID-19 outbreaks have affected restaurants throughout Los Angeles County, from a Panda Express in Sun Valley to the University of California's Bruin Cafe. If you live in Los Angeles, you can access health department reports about these outbreaks online.

1 Dec 2020

Chinese woman still sheds SARS-CoV-2 over four months post-infection

A new study by Chinese scientists explore an unusual case of extended viral shedding in a 68-year-old woman up to four months post-infection.

1 Dec 2020

SEAR implemented measures for successful continuation of essential HIV services during COVID 19

The COVID-19 pandemic was predicted to and has had a major impact on the essential HIV health services in the South East Asia Region (SEAR), putting at risk the benefits accrued over the last two decades. Apart from the risks posed by the virus to the individual health of people living with HIV (PLHIV), COVID-19 has disrupted essential services causing considerable delays in the delivery of medicines and other health commodities.

1 Dec 2020

Researchers successfully edit SIV virus from genomes of non-human primates

Taking a major step forward in HIV research, scientists at the Lewis Katz School of Medicine at Temple University have successfully edited SIV - a virus closely related to HIV, the cause of AIDS - from the genomes of non-human primates.

1 Dec 2020

New method could help determine the most appropriate treatment for HIV patients

A team co-led by a scientist at the University of California, Riverside, has developed a method to study how HIV mutates to escape the immune system in multiple individuals, which could inform HIV vaccine design.

30 Nov 2020

Researchers reveal how SARS-CoV-2 reaches the brain

Using post-mortem tissue samples, a team of researchers from Charité - Universitätsmedizin Berlin have studied the mechanisms by which the novel coronavirus can reach the brains of patients with COVID-19, and how the immune system responds to the virus once it does.

30 Nov 2020

HIV News and Research

UofL receives DoD funding to develop a nasal spray for preventing COVID-19

WHO highlights leading causes of mortality and morbidity worldwide from 2000 to 2019

HIV/AIDS testing and treatment can be adapted to achieve similar interventions to mitigate COVID-19

Scientists identify two drug candidates that counteract deficiencies caused by lack of MECP2 gene

People with Bartonella infection exhibit neuropsychiatric symptoms, skin lesions

Clinical investigators present abstracts on hematological malignancies at ASH Annual Meeting and Exposition

CRISPR-based test could provide rapid, low-cost testing to help control COVID-19 spread

The vaginal microbiome may impact the efficacy of HIV prevention therapy

Despite new CDC guidance, opioid prescription rates have not declined

Global solidarity, resilient services to reduce TB deaths among people living with HIV

Pharmacophore model helps find key protease inhibitor responsible for COVID-19

New research project to develop and test novel intervention for individuals with HIV/AIDS

HIV 'wonder drug' may not be as effective as hoped in sub-Saharan Africa, study suggests

Potential SARS-CoV-2 antiviral: Ionophore X-206 found to inhibit viral replication in cell cultures

Where COVID is on the menu: Failed contact tracing leaves diners in the dark

Chinese woman still sheds SARS-CoV-2 over four months post-infection

SEAR implemented measures for successful continuation of essential HIV services during COVID 19

Researchers successfully edit SIV virus from genomes of non-human primates

New method could help determine the most appropriate treatment for HIV patients

Researchers reveal how SARS-CoV-2 reaches the brain

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