Lungs News and Research

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Attenuated virulence and protective immunity in SARS-CoV-2 with a mutation in the S1/S2 cleavage site

A new study published in mBio investigates the impact of the furin cleavage site on viral growth and pathogenesis.

31 Aug 2021

Telemedicine appointments reduce risk of further illness in children with medical complexity

Telemedicine appointments combined with in-person visits significantly reduced the risk of further illness for children with medically complex cases, according to results of a new study by researchers with The University of Texas Health Science Center at Houston.

31 Aug 2021

Researchers develop adult lung organoids that represent all cell types

Since the COVID-19 pandemic reached the United States in early 2020, scientists have struggled to find laboratory models of SARS-CoV-2 infection, the respiratory virus that causes COVID-19. Animal models fell short; attempts to grow adult human lungs have historically failed because not all of the cell types survived.

31 Aug 2021

Coronavirus buildup in the lungs is likely behind high mortality rates

A buildup of coronavirus in the lungs is likely behind the steep mortality rates seen in the pandemic, a new study finds.

31 Aug 2021

Will mRNA vaccine boosters be required for SARS-CoV-2 variants?

A new study shows that the highly effective mRNA Moderna vaccine designed against the original SARS-CoV-2 strain may lose some efficacy as new variants arise.

30 Aug 2021

Researchers analyze dynamic changes in chest CT images over 167 days in 11 COVID-19 patients

Announcing a new article publication for Zoonoses journal. In this article the authors Jianqin Liang, Guizeng Liu, Shuzhuang Yu, Yang Yang, Yanchun Li, Hongli Tian, Zhe Chen and Wenping Gong The Eighth Medical Center of PLA General Hospital, Beijing, China and Nanpi County People's Hospital, Hebei, China discuss dynamic changes in chest CT images over 167 days in 11 patients with COVID-19.

28 Aug 2021

PETA scientists come up with state-of-the-art tools to implement animal-free research

This week marks the 11th World Congress on Alternatives and Animal Use in the Life Sciences, and the thousands of scientists attending this year's virtual conference will hear from PETA scientists on matters ranging from scientific and ethical concerns regarding inflicting permanent brain damage on primates to toxicity testing in rabbits.

28 Aug 2021

Study: One half of hospitalized COVID-19 patients experience persistent symptoms after one year

Most symptoms of COVID-19 in hospitalized patients are resolved within 12 months, however, around one half still experience at least one persistent symptom, a study of 1,276 patients from Wuhan, China, published in The Lancet, has found.

27 Aug 2021

Fine particle pollution doubles the risk of Alzheimer's disease in Black women

Fine particle pollution may be one reason why Black women have double the risk of developing Alzheimer's than white women, suggests new research from the Keck School of Medicine of USC.

27 Aug 2021

Pregnant women with COVID-19 are more susceptible to pre-eclampsia

A review of the scientific literature published by Brazilian researchers shows that pregnant women infected by the novel coronavirus run a higher risk of developing pre-eclampsia, a pregnancy complication characterized by persistent high blood pressure, usually in the second half of pregnancy or shortly after delivery.

26 Aug 2021

Researchers find clues to how lung damage develops in the aftermath of a respiratory infection

The deadliest time in a viral respiratory illness sometimes is actually after the virus is cleared from the body. Destructive processes that are set in motion during an infection crest in the weeks after the virus is defeated, leading to organ damage that can cause chronic illness or even death.

24 Aug 2021

UC San Diego Health performed region’s first double lung transplant for a COVID-19 patient

On a July afternoon, Federico Gomez Gil, 56, is dressed in a short-sleeved, collared shirt, sweatpants and a baseball cap. He sits in a chair in a hospital room, surrounded by his wife and two daughters. Given the past five months, this is the moment of a lifetime — a new lifetime.

24 Aug 2021

Peptoids could one day cure or prevent herpes, COVID-19

In addition to antibodies and white blood cells, the immune system deploys peptides to fight viruses and other pathogens.

24 Aug 2021

Antiviral strategy using synthetic peptoid has promising implications for fighting infection

Scientists have manufactured a synthetic form of peptide to combat viral infections, with tests already conducted on HSV-1 as well as SARS-CoV-2.

24 Aug 2021

Researchers develop brain organoids that show neural activity similar to living human brains

Researchers at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have developed brain organoids -; 3D, brain-like structures grown from human stem cells -; that show organized waves of activity similar to those found in living human brains.

24 Aug 2021

Study suggests a novel therapeutic target to reverse lung fibrosis

Researchers have reversed lung fibrosis in a mouse model of idiopathic pulmonary fibrosis, or IPF, as reported in a study published in the journal Cell Death and Differentiation.

24 Aug 2021

Study: Awake prone positioning can reduce the need for mechanical ventilation in COVID-19 patients

A six country clinical study of more than 1,100 hospitalized COVID-19 patients who required high-flow nasal cannula oxygen therapy suggests that prone positioning (rotating patients with severe breathing issues so they are face down) soon after admission can significantly reduce the need for mechanical ventilation.

23 Aug 2021

Exposure to wildfire smoke during pregnancy raises risk for preterm birth

Exposure to wildfire smoke during pregnancy increases the risk that a baby will be born too early, a new Stanford University study suggests.

23 Aug 2021

Research finds potential overuse of antibiotics in patients with severe SARS-CoV-2 pneumonia

Only 21 percent of patients with severe pneumonia caused by SARS-CoV-2 (the virus that causes COVID-19) have a documented bacterial superinfection at the time of intubation, resulting in potential overuse of antibiotics, according to new research published online in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine.

20 Aug 2021

HMGA1 plays role in gastric cancer cell proliferation and metastasis

Aging-US published "HMGA1 promotes gastric cancer growth and metastasis by transactivating SUZ12 and CCDC43 expression" which reported that HMGA1 is overexpressed in GC cells and the high expression of HMGA1 was correlated with worse survival in GC patients using a bioinformatics assay.

19 Aug 2021

Lungs News and Research

Attenuated virulence and protective immunity in SARS-CoV-2 with a mutation in the S1/S2 cleavage site

Telemedicine appointments reduce risk of further illness in children with medical complexity

Researchers develop adult lung organoids that represent all cell types

Coronavirus buildup in the lungs is likely behind high mortality rates

Will mRNA vaccine boosters be required for SARS-CoV-2 variants?

Researchers analyze dynamic changes in chest CT images over 167 days in 11 COVID-19 patients

PETA scientists come up with state-of-the-art tools to implement animal-free research

Study: One half of hospitalized COVID-19 patients experience persistent symptoms after one year

Fine particle pollution doubles the risk of Alzheimer's disease in Black women

Pregnant women with COVID-19 are more susceptible to pre-eclampsia

Researchers find clues to how lung damage develops in the aftermath of a respiratory infection

UC San Diego Health performed region’s first double lung transplant for a COVID-19 patient

Peptoids could one day cure or prevent herpes, COVID-19

Antiviral strategy using synthetic peptoid has promising implications for fighting infection

Researchers develop brain organoids that show neural activity similar to living human brains

Study suggests a novel therapeutic target to reverse lung fibrosis

Study: Awake prone positioning can reduce the need for mechanical ventilation in COVID-19 patients

Exposure to wildfire smoke during pregnancy raises risk for preterm birth

Research finds potential overuse of antibiotics in patients with severe SARS-CoV-2 pneumonia

HMGA1 plays role in gastric cancer cell proliferation and metastasis

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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