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New study sheds light on role of type II collagen in rheumatoid arthritis

Rheumatoid arthritis (RA) is an autoimmune disease which gradually erodes cartilage and bone and is characterised by chronic inflammation of the joints.

6 Dec 2005

Fibroblast research could lead to alternatives to implanted electronic pacemakers

In guinea pig experiments, Johns Hopkins scientists fused common connective tissue cells taken from lungs with heart muscle cells to create a safe and effective biological pacemaker whose cells can fire on their own and naturally regulate the muscle's rhythmic beat.

5 Dec 2005

Alagebrium may prevent arterial aging in patients with systolic hypertension

A compound called alagebrium, which is very similar to another used in anti-wrinkle creams, may be useful in reducing the deleterious effects of arterial aging in the majority of elderly Americans with systolic hypertension, a new study from researchers at Johns Hopkins shows.

5 Dec 2005

Findings may help in development of new anti-inflammatory compounds

Virginia Commonwealth University researchers studying the enzyme that triggers inflammation have found that it may be a target for a new class of anti-inflammatory drugs to treat arthritis, asthma, multiple sclerosis, lung and colon cancers and Alzheimer's disease.

2 Dec 2005

Significant relationships between household endotoxin and diagnosed asthma

Exposure to household endotoxin levels poses a significant risk for asthma, according to the first nationwide sampling of house dust.

2 Dec 2005

Drinking lots of coffee and tea can reduce the risk of chronic liver disease

A study published in the American Gastroenterological Association (AGA) journal Gastroenterology found that people at high risk for liver injury may be able to reduce their risk for developing chronic liver disease significantly by drinking more than two cups of coffee or tea daily.

2 Dec 2005

Mycophenolate mofetil helps treat lupus patients

Treating lupus patients suffering from kidney inflammation with a medicine known as mycophenolate mofetil may be more effective in inducing remission than treating them with the standard regimen of intravenous cyclophosphamide (Cytoxan), a new clinical trial indicates.

2 Dec 2005

Cellular and molecular mechanisms that accelerate the development and progression of atherosclerosis

A McMaster University study on atherosclerosis will be featured on the cover of the December issue of the high impact American Heart Association scientific journal, Arteriosclerosis, Thrombosis and Vascular Biology.

2 Dec 2005

Risk of severe asthma episodes predicted from fluctuation analysis of airway function

A startling new study published in the science journal Nature this week (Nature Vol 438, issue 7068, pp 667-670) reveals that inhalers used by asthmatics for symptomatic relief of their condition might actually increase the likelihood of an acute attack.

30 Nov 2005

Study finds common pollutants linked to fetal growth retardation

Babies born to women exposed to high ozone levels during pregnancy are at heightened risk for being significantly underweight, according to researchers at the Keck School of Medicine of the University of Southern California.

26 Nov 2005

Tuberculosis research

It is estimated that two billion people--or one-third of the world's population--are chronically infected without active symptoms. Nine million new cases of active disease are diagnosed annually, resulting in two million deaths.

26 Nov 2005

Stress shown to raise bad cholesterol levels

British scientists have found that cholesterol levels in healthy adults can be raised by stress.

24 Nov 2005

New drug CellCept far more effective in treating kidney problems in lupus patients

A new study has shown that the drug CellCept is just as good at fighting kidney complications from the debilitating disease lupus with far fewer side effects than standard treatment using the cancer drug Cytoxan.

24 Nov 2005

Valproic acid (Depakote) may help treat lupus

A common anti-seizure drug may be effective against certain conditions associated with lupus, according to animal research at Wake Forest University School of Medicine.

20 Nov 2005

Allergists help manage asthma better

Compared to patients receiving care from primary care physicians, asthma patients who are under the care of an allergist report fewer asthma control problems and less sever asthma symptoms, according to new research in the December 2005 Journal of Allergy & Clinical Immunology (JACI).

20 Nov 2005

First nationwide study of pregnancy outcomes in women with rheumatic disease

The first nationwide study of pregnancy outcomes in women with rheumatic disease confirms that they experience greater pregnancy risks and longer hospital stays than the average pregnant woman.

20 Nov 2005

Trichostatin A may fight lupus and atherosclerosis simultaneously

People with lupus are prone to premature accelerated atherosclerosis. Now scientists at Wake Forest University School of Medicine think they have a way to prevent or decrease this atherosclerosis and prevent heart attacks.

16 Nov 2005

Lack of aggressive treatment for clogged leg blood vessels means missed heart attack prevention opportunity

Despite the fact that clogged arteries in the legs usually mean clogged arteries near the heart, doctors often fail to give heart-protecting drugs to people with severe leg blood vessel blockages, a new University of Michigan-led study finds.

15 Nov 2005

Edifoligide no better than placebo for clogged veins

A new drug, edifoligide, designed to prevent the clogging of veins used in coronary bypass surgery was no more effective than a placebo, according to the results of a Phase III clinical trial led by researchers at Duke Clinical Research Institute (DCRI).

14 Nov 2005

New respiratory synctial virus treatment for at-risk infants under study

A new, enhanced-potency onoclonal antibody designed to keep the sniffles from turning into a devasting illness in at-risk babies is under study at the Medical College of Georgia Children's Medical Center.

14 Nov 2005