Insulin News and Research

RSS

Insulin is a hormone that is needed to convert glucose, starches and other food into energy needed for daily life. Insulin allows cells to use glucose for fuel and is secreted by beta cells in the islets of Langerhans. The release of insulin from the pancreas is stimulated by increased blood glucose, vagal nerve stimulation, and other factors. Insulin is obtained from various animals and available in a variety of preparations. Commercial insulin preparations differ in a number of ways, including differences in the animal species from which they are obtained; their purity, concentration, and solubility; and the time of onset and duration of their biologic action. An oral hypoglycemic agent is not a form of insulin therapy.

Glucagon resistance: A new biological concept in the fight against diabetes

Researchers from the University of Copenhagen are introducing a new biological concept in the fight against diabetes: glucagon resistance.

17 Sep 2020

A ferry protein in the pancreas safeguards beta-cells from high-fat diet induced stress

Every time we eat, the glucose level in our body goes up. This spurs our pancreatic machinery into action and through intricate physiological mechanisms, appropriate amounts of insulin are produced, our blood glucose levels are controlled, and we remain healthy.

16 Sep 2020

NTU-incubated start-up plans clinical trial of new slow-release pill for Parkinson’s disease

Materials scientists from Nanyang Technological University, Singapore (NTU Singapore) have developed a new pill which uses the stomach as a drug reservoir and delivers medicines slowly over time to patients with Parkinson's disease (PD).

16 Sep 2020

Enzyme insight could lead to new treatment approach for diabetic patients

Research led by the Centenary Institute has discovered that the lack of an enzyme in the liver called sphingosine kinase 2 results in pronounced insulin resistance and glucose intolerance, both symptoms of early stage type 2 diabetes.

15 Sep 2020

Research provides insight into how muscles and fat tissue communicate to improve fitness

Why does exercise training make you more fit? It's well established that exercising enhances insulin sensitivity and improves our metabolism that, in turn, increases exercise performance. But the biological mechanisms underlying this adaptation are not fully understood.

14 Sep 2020

Heat and gut microbiota promote stronger bones

Osteoporosis, a bone disease linked to ageing, is characterized by a loss of bone density, micro-architectural deterioration of the bones and an increased risk of fractures.

11 Sep 2020

Portable, low-field MRI device can be safely used at patient bedside, shows study

A portable, low-field magnetic resonance imaging (MRI) device can be safely used at bedside in complex clinical care settings to evaluate critically-ill patients for suspected stroke, traumatic brain injury (TBI), or other neurological problems, results of a proof-of-concept study show.

11 Sep 2020

Researchers investigate the effects of endurance training on cellular respiration

In obese individuals, endurance exercise improves fitness and increases the number of mitochondria * and cellular respiration in skeletal muscles.

10 Sep 2020

Researchers identify proinflammatory lipids that precede onset of Type 1 diabetes in mouse model, children

Type 1 diabetes, or T1D, is an autoimmune disease in which the body's immune cells -; led by inflammatory macrophages -; attack and destroy the beta cells of the pancreas that produce insulin.

10 Sep 2020

An ingestible capsule for sampling of gut microbiota and biomarkers

Gut microbes affect human health, but there is still much to learn, in part because they're not easy to collect.

9 Sep 2020

Obamacare co-ops down from 23 to final ‘3 little miracles’

New Mexico Health Connections' decision to close at year's end will leave just three of the 23 nonprofit health insurance co-ops that sprang from the Affordable Care Act.

9 Sep 2020

Blanket approach to prescribing medication during pregnancy may put low birth weight babies at risk

New research led by the University of South Australia shows that a blanket approach to prescribing medication during pregnancy may put low birth weight babies at risk for the rest of their lives.

8 Sep 2020

Probiotics may help manage obesity in younger population

Probiotics may help children and adolescents with obesity lose weight when taken alongside a calorie-controlled diet, according to a study being presented at e-ECE 2020.

7 Sep 2020

Researchers develop novel model to study factors that cause type 2 diabetes

Using cells taken from patients with type 2 diabetes and new techniques to convert them into specialized precursors of muscle cells, researchers have developed a novel 'disease-in-a-dish' model to study the basic molecular factors that lead to the development of type 2 diabetes.

4 Sep 2020

New intervention to help improve outcomes for adolescents with Type 1 diabetes

Adolescence is a difficult period of development, made more complex for those with Type 1 diabetes mellitus (T1DM).

3 Sep 2020

Study shows link between lipid metabolism and onset of psychosis

Changes in blood lipids give an early warning for the development of psychosis in individuals who are at risk. Weight gain displays the same connection. This is shown in a new study at örebro University.

2 Sep 2020

ACE2/TMPRSS2 not expressed in pancreatic islet endocrine cells

A new study by researchers at the Vanderbilt University Medical Center and the University of Pennsylvania Perelman School of Medicine and published on the preprint server bioRxiv* in August 2020 reports that both key enzymes that are required for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) entry into the human host cell are lacking in the beta cells of the pancreatic islet. This rules out the direct injury hypothesis for impaired glucose control in patients with COVID-19 disease.

1 Sep 2020

Negligible ACE2 expression in human beta-cells

Now, a new study published on the preprint server bioRxiv reports that even though the fatality rate is significantly higher in diabetics, there is no evidence that this is due to direct viral infection of pancreatic beta cells, which produce the key hormone in glucose homeostasis, namely insulin.

1 Sep 2020

Brain estrogen critical for astrocyte activation and neuroprotection

When the brain isn't getting enough oxygen, estrogen produced by neurons in both males and females hyperactivates another brain cell type called astrocytes to step up their usual support and protect brain function.

1 Sep 2020

New microgel drug delivery method could improve effectiveness of pancreatic islet transplants

Pancreatic islet transplants, which revive insulin production to treat type 1 diabetes, only last an average of three years.

31 Aug 2020

Insulin News and Research

Further Reading

Glucagon resistance: A new biological concept in the fight against diabetes

A ferry protein in the pancreas safeguards beta-cells from high-fat diet induced stress

NTU-incubated start-up plans clinical trial of new slow-release pill for Parkinson’s disease

Enzyme insight could lead to new treatment approach for diabetic patients

Research provides insight into how muscles and fat tissue communicate to improve fitness

Heat and gut microbiota promote stronger bones

Portable, low-field MRI device can be safely used at patient bedside, shows study

Researchers investigate the effects of endurance training on cellular respiration

Researchers identify proinflammatory lipids that precede onset of Type 1 diabetes in mouse model, children

An ingestible capsule for sampling of gut microbiota and biomarkers

Obamacare co-ops down from 23 to final ‘3 little miracles’

Blanket approach to prescribing medication during pregnancy may put low birth weight babies at risk

Probiotics may help manage obesity in younger population

Researchers develop novel model to study factors that cause type 2 diabetes

New intervention to help improve outcomes for adolescents with Type 1 diabetes

Study shows link between lipid metabolism and onset of psychosis

ACE2/TMPRSS2 not expressed in pancreatic islet endocrine cells

Negligible ACE2 expression in human beta-cells

Brain estrogen critical for astrocyte activation and neuroprotection

New microgel drug delivery method could improve effectiveness of pancreatic islet transplants

Shaping the Future of Neuroscience: A Conversation with Atlas Antibodies on the MolBoolean™ and the Impact of SfN 2024

How the Arts Reshape Brain Function: Susan Magsamen on the Future of Neuroaesthetics

Inside the Alzheimer's Association: Dr. Heather Snyder on Driving Research and Collaboration

Latest News