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Next-gen intranasal vaccine takes on measles, mumps, and multiple COVID-19 variants in one shot

Researchers developed an intranasal trivalent measles-mumps-SARS-CoV-2 vaccine that provides robust protection against multiple coronavirus variants. Leveraging the established measles-mumps-rubella platform, this vaccine demonstrates broad and adaptable immune responses, especially against Delta and Omicron variants.

8 Oct 2023

Pre-existing CMV immunity protects mothers and babies from transmission and birth defects

Researchers at Tulane University have shown for the first time that mothers are much less likely to transmit a common virus known to cause miscarriages and birth defects if they are exposed to the virus prior to becoming pregnant.

6 Oct 2023

Could infants' robust immune responses reshape future vaccination strategies?

Utilizing next-gen sequencing techniques, researchers analyzed infants' immune responses to infections, uncovering a predominant innate immune activation unlike adults and older children. This insight could steer child vaccination research and pediatric infection management strategies, potentially revolutionizing infant healthcare.

3 Oct 2023

Ginger shows promise as a natural defense against autoimmune diseases

Comprehensive study reveals that whole ginger extracts have a significant impact on inhibiting neutrophil hyperactivity, a key factor in autoimmune diseases like APS and lupus. Consuming ginger for just a week showed promising results in both animal models and human trials, positioning it as a natural and affordable treatment option for a range of autoimmune disorders.

2 Oct 2023

Zoonotic spillover safeguarding: computationally designed antigen targets range of coronaviruses

Researchers used an interdisciplinary approach incorporating phylogenetics, 3D protein modeling, and plasmid design to identify and computationally design an antigen representing the core of most currently known sarbecoviruses.

27 Sep 2023

Arrayed CRISPR Screening for Revolutionizing Target Discovery

In this interview conducted at SLAS EU 2023 in Brussels, Belgium, we spoke to Ulrike Kuenzel, Associate Director in the Functional Genomics department at AstraZeneca about the application of arrayed CRISPR screening for target identification and more.

From Society for Laboratory Automation and Screening (SLAS) 27 Sep 2023

One gene variant could be a shield against severe COVID-19 lung damage

Researchers identify a specific genetic variant, rs2204985, linked to less severe lung involvement and a stronger immune response in COVID-19 patients with severe pneumonia. The study suggests that understanding this genetic marker could help identify high-risk individuals and enhance strategies for prevention and treatment.

25 Sep 2023

Researchers identify a rare cause of male infertility and discover a potential cure

Researchers investigated the genetic underpinning of asthenozoospermia, the leading cause of male fertility.

18 Sep 2023

Single-cell screening of cerebral organoids to identify developmental defects in autism

Researchers develop CRISPR-human organoids-single-cell RNA sequencing system to identify developmental brain defects in autism.

18 Sep 2023

Wireless molecular-electrical communications for tumor-cell-induced apoptosis

Researchers utilize electricity generated by wireless-induced redox interactions at bio-nanoantennae to cause apoptosis in cancerous cells.

18 Sep 2023

Dormant HIV reservoirs can spontaneously produce RNA and proteins, study finds

HIV anti-retroviral therapy is considered a treatment and not a cure because patients usually carry a reservoir of HIV-infected cells that can re-emerge if treatment stops.

13 Sep 2023

How COVID-19 targets the pancreas revealed

The study uncovers the role of the PLAC8 protein in making the human pancreas vulnerable to SARS-CoV-2 infection, leading to pancreatic injury and complications in severe COVID-19 cases. The findings open up new avenues for understanding how the virus affects multiple organ systems and offer a potential target for future treatments.

12 Sep 2023

New class of iron-targeting compounds found to hamper proliferation of cancer cells

Researchers at the University of Arizona Cancer Center discovered a new class of iron-targeting compounds that hamper the proliferation of cultured malignant cells in a laboratory setting.

12 Sep 2023

Herring roe oil's potential in psoriasis treatment

Researchers investigated the use of herring row oil to treat psoriasis, a non-communicable skin disease.

12 Sep 2023

Early viral exposure in mice weakens vaccine response, raising questions for human studies

Researchers at Washington University have demonstrated that early life exposure to multiple viruses in house mice dampens the immune response to SARS-CoV-2 vaccinations later in life. The study raises concerns about the applicability of common mouse models in immunological research, suggesting that prior pathogen exposure could be a significant variable in predicting vaccine efficacy.

5 Sep 2023

Bio-Rad enhances flow cytometry capabilities for veterinary immunology research with new StarBright Dyes

Bio-Rad Laboratories, Inc., a global leader in life science research and clinical diagnostic products, today announced the launch of the 29th StarBright Dye, StarBright Red 670, and an expansion of its current range with 29 additional highly validated antibodies conjugated to StarBright Blue 700 and StarBright Violet 610 Dyes.

From Bio-Rad Laboratories 30 Aug 2023

Study suggests whole egg consumption has benefits over egg white consumption in young, healthy adults

Researchers investigated the impacts of different egg-based diets on healthy young individuals' immune, hematologic, and metabolic clinical profiles.

30 Aug 2023

Unlocking tumor immune evasion: IL1RL1+ Treg cells and CAFs collaborate for immunotherapy resistance

Researchers demonstrated that the crosstalk between IL1RL1+ regulatory T-cells (Treg) and cancer-associated fibroblasts (CAFs) drives the tissue repairing.

30 Aug 2023

Innovative insights into effects of hematopoietic changes on colon cancer, unveiling therapeutic avenues

Researchers investigated whether bone marrow-derived cells contribute to colitis-associated colon cancer.

29 Aug 2023

Study unveils previously unknown urinary biomarkers, revolutionizing early detection and treatment of viral infections like COVID-19

This recent study identifies new urinary biomarkers for detecting acute COVID-19 using spectroscopic analysis. The findings reveal that these biomarkers could offer valuable tools for early diagnosis, understanding the severity of the disease, and possibly contribute to endogenous immunological defense mechanisms against SARS-CoV-2.

29 Aug 2023

Cytometry News and Research

Next-gen intranasal vaccine takes on measles, mumps, and multiple COVID-19 variants in one shot

Pre-existing CMV immunity protects mothers and babies from transmission and birth defects

Could infants' robust immune responses reshape future vaccination strategies?

Ginger shows promise as a natural defense against autoimmune diseases

Zoonotic spillover safeguarding: computationally designed antigen targets range of coronaviruses

Arrayed CRISPR Screening for Revolutionizing Target Discovery

One gene variant could be a shield against severe COVID-19 lung damage

Researchers identify a rare cause of male infertility and discover a potential cure

Single-cell screening of cerebral organoids to identify developmental defects in autism

Wireless molecular-electrical communications for tumor-cell-induced apoptosis

Dormant HIV reservoirs can spontaneously produce RNA and proteins, study finds

How COVID-19 targets the pancreas revealed

New class of iron-targeting compounds found to hamper proliferation of cancer cells

Herring roe oil's potential in psoriasis treatment

Early viral exposure in mice weakens vaccine response, raising questions for human studies

Bio-Rad enhances flow cytometry capabilities for veterinary immunology research with new StarBright Dyes

Study suggests whole egg consumption has benefits over egg white consumption in young, healthy adults

Unlocking tumor immune evasion: IL1RL1+ Treg cells and CAFs collaborate for immunotherapy resistance

Innovative insights into effects of hematopoietic changes on colon cancer, unveiling therapeutic avenues

Study unveils previously unknown urinary biomarkers, revolutionizing early detection and treatment of viral infections like COVID-19

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Expanding research and clinical options for children with cancer

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