Drugs News and Research

RSS

Nuclera eProtein Discovery system installed at leading academic institutes

Novel platform automates and accelerates protein production, enabling scale-up to mg amount in less than 48 hours.

From Nuclera 2 May 2024

High testosterone levels in older men associated with greater risk of atrial fibrillation

Researchers investigated whether higher endogenous testosterone levels increase atrial fibrillation (AF) risk among healthy older males.

2 May 2024

New drug candidate reverses obesity in mice by transforming liver metabolism

A mitochondrial transcription inhibitor (IMT) shifted metabolism in high-fat diet mice toward fatty acid oxidation, leading to weight loss, reduced liver fat, and improved glucose tolerance.

1 May 2024

Study uncovers molecular mechanism linking nonsense-mediated RNA decay to microcephaly

Nonsense-mediated RNA decay, or NMD, is an evolutionarily conserved molecular mechanism in which potentially defective messenger RNAs, or mRNAs (genetic material that instructs the body on how to make proteins), are degraded.

1 May 2024

Psilocybin found to be more effective than controls for treating depression symptoms

Psilocybin - the active ingredient in "magic" mushrooms - is a more effective treatment for symptoms of depression than controls, providing further support for its potential as an antidepressant, suggests a study published by The BMJ today.

1 May 2024

Cancer-like cells found in clogged arteries aggravate atherosclerosis

Columbia University researchers have found cells inside clogged arteries share similarities with cancer and aggravate atherosclerosis, raising the possibility that anticancer drugs could be used to treat atherosclerosis and prevent heart attacks.

1 May 2024

Study investigates senescent phenotypes of human corneal endothelial cells upon UV-A exposure

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 8, entitled, "Senescent characteristics of human corneal endothelial cells upon ultraviolet-A exposure."

30 Apr 2024

New monoclonal antibody vaccine slashes malaria risk in children

A recent study demonstrates that the monoclonal antibody-based vaccine L9LS is safe for children aged 6 to 10 and significantly reduces the risk of malaria infection and clinical symptoms by 70% and 77%, respectively.

30 Apr 2024

Gut bacteria and urinary infections linked, offering new angles for treatment

A study in eClinicalMedicine explores the relationship between gut microbiota, urinary tract colonization, and recurrent urinary tract infections (rUTI), suggesting the cross-habitation of uropathogenic E. coli as a significant mechanism in rUTI recurrence.

30 Apr 2024

New approach to inhibit strep’s DNA-cleaving enzymes

An entirely new approach to inhibiting DNA-cleaving enzymes works through the aggregation of an otherwise non-toxic molecule.

30 Apr 2024

Specific class of drugs can reverse diet-induced obesity, fatty liver and diabetes in mice

Researchers at Karolinska Institutet may have found a new way to treat obesity and related disorders by targeting the cells' powerhouses, the mitochondria.

30 Apr 2024

Fentanyl inhalation linked to irreversible brain damage

Inhaling the synthetic opioid fentanyl may cause potentially irreversible brain damage (toxic leukoencephalopathy), warn doctors in the journal BMJ Case Reports, after treating a middle aged man found unresponsive in his hotel room after snorting the drug.

29 Apr 2024

Exhaled breath may be a promising avenue for antibiotic monitoring

Exhaled breath may be very promising alternative to blood for the therapeutic monitoring of antibiotics, the ESCMID Global Congress (formerly ECCMID) in Barcelona, Spain (27-30 April) will hear.

29 Apr 2024

New Kaposi sarcoma mouse model could be key to drug development

Researchers at UNC Lineberger Comprehensive Cancer Center, after decades of research efforts, have developed a mouse model of Kaposi sarcoma that could be key to the development of new drugs to treat the disease.

29 Apr 2024

Study reveals brown fat's built-in mechanism and potential obesity treatment

Brown fat, also known as brown adipose tissue (BAT), is a type of fat in our bodies that's different from the white fat around our belly and thighs that we are more familiar with.

29 Apr 2024

Ancient grains show promise for type 2 diabetes

A meta-analysis in the journal Nutrition, Metabolism and Cardiovascular Diseases finds that ancient grains like oats, brown rice, and millet may improve lipid profiles in type 2 diabetes patients, but variations in study designs call for further research to confirm these benefits.

29 Apr 2024

Parkinson’s UK invests £2.1 million in Neumora Therapeutics for preclinical testing of new Parkinson’s drug

Parkinson’s UK is investing £2.1million to support Neumora Therapeutics to carry out preclinical testing of NMRA-NLRP3, a NLRP3 inhibitor with the potential to reduce inflammation and protect brain cells in Parkinson’s. NLRP3 is a protein that plays a role in regulating a number of inflammatory processes that are believed to contribute to the damage to brain cells that underlies Parkinson’s.

27 Apr 2024