Genomics News and Research

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Genomics is the study of the complete genetic material, including genes and their functions, of an organism.

NIH funds $12.5 million initiative to create the world's first integrated pancreas knowledgebase

Leading investigators in diabetes, pancreas and islet biology, and computational biology have received $12.5 million in two five-year awards from the National Institutes of Health to create the world's first, integrated knowledgebase of human-derived tissue- and cellular-level pancreatic information to support innovative, collaborative and reproducible research.

25 Mar 2024

Scientists shed light on key immune regulators involved in Alzheimer’s and other disorders of lipid-rich tissues

Using novel genetic and genomic tools, researchers at the Icahn School of Medicine at Mount Sinai have shed light on the role of immune cells called macrophages in lipid-rich tissues like the brain, advancing our understanding of Alzheimer's and other diseases.

21 Mar 2024

Study reveals cellular dynamics of multiple sclerosis lesions

Using advanced methodology, scientists in Sweden were able to reveal at the cellular level how lesions in multiple sclerosis develop.

20 Mar 2024

Genetic test can identify how patients with triple negative early-stage breast cancer will respond to immunotherapy

Researchers have developed a genetic test that can identify how patients with triple negative early-stage breast cancer will respond to immunotherapy drugs.

20 Mar 2024

NUS study reveals key mechanisms behind drug resistance in relapsed acute myeloid leukemia

Scientists from the National University of Singapore (NUS) have discovered that the evasion of apoptosis is a key driver of drug resistance in patients with relapsed acute myeloid leukaemia (AML), a type of aggressive blood cancer.

19 Mar 2024

Severity of current SARS-CoV-2 variants is not linked to the number of mutations

New research from UNC Charlotte's Center for Computational Intelligence to Predict Health and Environmental Risks (CIPHER) has found that the two most prevalent strains of the virus that cause COVID-19, SARS-CoV-2 variants BA.2.86 and JN.1, are not significantly better than their predecessor Omicron at evading immune responses and causing infections despite having a high number of mutations compared to previous variants.

19 Mar 2024

Study uncovers how APOBEC enzymes drive cancer mutations

A research team led by the University of California, Irvine has discovered the key role that the APOBEC3A and APOBEC3B enzymes play in driving cancer mutations by modifying the DNA in tumor genomes, offering potential new targets for intervention strategies.

18 Mar 2024

CHOP study uncovers metabolic key to faster immune response

Researchers from Children's Hospital of Philadelphia identified a key metabolite in cells that helps direct immune responses and explains at a single cell level why immune cells that most efficiently recognize pathogens, vaccines, or diseased cells grow and divide faster than other cells.

15 Mar 2024

Understanding the genetic and cellular impact of smoking

It's no secret that smoking is extremely detrimental to health. Tobacco smoke contains thousands of chemicals, including carcinogens, increasing the risk of cancer, cardiovascular and respiratory diseases.

14 Mar 2024

Rapid, easy-to-use diagnostic test could save more lives from melioidosis

Globally, more than half of patients die after infection with the neglected tropical disease, melioidosis, often before they are diagnosed.

13 Mar 2024

Unveiling mechanisms of relapse in small cell lung cancer under therapy

Small cell lung cancer (SCLC) is a highly aggressive tumor of the lung that occurs especially in heavy smokers.

13 Mar 2024

Ricoh and ERS Genomics enter into CRISPR/Cas9 license agreement

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From ERS Genomics 13 Mar 2024

New custom-designed proteins can efficiently reach intramembrane targets

Hitting targets embedded within the cell membrane has long been difficult for drug developers due to the membrane's challenging biochemical properties. Now, Scripps Research chemists have demonstrated new custom-designed proteins that can efficiently reach these "intramembrane" targets.

13 Mar 2024

Tracing Monkeypox virus: Leveraging ancient orangutan DNA to investigate the 1965 Rotterdam Zoo outbreak

Ancient DNA analysis of museum-preserved orangutan teeth reveals the cause of the 1965 zoo outbreak in the Netherlands as monkeypox virus (MPXV) infections, demonstrating the power of museomic techniques in tracing historic viral transmissions.

12 Mar 2024

Protein Kdm1a plays a crucial role in preserving neuronal identity, study shows

Epigenetic processes allow different cell types to emerge from a single genome. Throughout development, cells differentiate and acquire distinct characteristics by expressing the same genome in different ways.

12 Mar 2024

Molecular Rosetta stone provides previously unknown insight into gut microbiome communication

Researchers from Skaggs School of Pharmacy and Pharmaceutical Sciences at the University of California San Diego have uncovered thousands of previously unknown bile acids, a type of molecule used by our gut microbiome to communicate with the rest of the body.

12 Mar 2024

Mount Sinai's new department will connect medical care with public health

The Icahn School of Medicine at Mount Sinai, fulfilling its commitment to connecting medical care with public health, today established a new Department of Public Health under the visionary leadership of Rosalind J. Wright, MD, MPH, the Horace W. Goldsmith Professor in Children's Health Research at Icahn Mount Sinai.

12 Mar 2024

Groundbreaking study unveils sex-specific genetic influences on blood pressure

Genetic heterogeneity of blood pressure (BP) effects between sexes.

12 Mar 2024

Scientists find answers about cardiovascular diseases by probing the cellular "glue"

University of Virginia School of Medicine scientists have found important answers about strokes, heart attacks and cardiovascular diseases by probing the biological glue our bodies create to protect us from those deadly dangers.

11 Mar 2024

Scripps Research tests wearable devices as relief for long COVID symptoms

Scientists at the Scripps Research Digital Trials Center have partnered with the health technology company CareEvolution to launch a remote study that will investigate whether wrist-worn devices, such as activity trackers and smartwatches, can help people with long COVID manage and reduce the severity of their symptoms.

11 Mar 2024

Genomics News and Research

Further Reading

NIH funds $12.5 million initiative to create the world's first integrated pancreas knowledgebase

Scientists shed light on key immune regulators involved in Alzheimer’s and other disorders of lipid-rich tissues

Study reveals cellular dynamics of multiple sclerosis lesions

Genetic test can identify how patients with triple negative early-stage breast cancer will respond to immunotherapy

NUS study reveals key mechanisms behind drug resistance in relapsed acute myeloid leukemia

Severity of current SARS-CoV-2 variants is not linked to the number of mutations

Study uncovers how APOBEC enzymes drive cancer mutations

CHOP study uncovers metabolic key to faster immune response

Understanding the genetic and cellular impact of smoking

Rapid, easy-to-use diagnostic test could save more lives from melioidosis

Unveiling mechanisms of relapse in small cell lung cancer under therapy

Ricoh and ERS Genomics enter into CRISPR/Cas9 license agreement

New custom-designed proteins can efficiently reach intramembrane targets

Tracing Monkeypox virus: Leveraging ancient orangutan DNA to investigate the 1965 Rotterdam Zoo outbreak

Protein Kdm1a plays a crucial role in preserving neuronal identity, study shows

Molecular Rosetta stone provides previously unknown insight into gut microbiome communication

Mount Sinai's new department will connect medical care with public health

Groundbreaking study unveils sex-specific genetic influences on blood pressure

Scientists find answers about cardiovascular diseases by probing the cellular "glue"

Scripps Research tests wearable devices as relief for long COVID symptoms

Sequencing & Genomics: Elevating Science and Healthcare eBook

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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