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Rutgers scientists create CRISPR-edited mice to study the neurobiology of Tourette disorder

In research that may be a step forward toward finding personalized treatments for Tourette disorder, scientists at Rutgers University–New Brunswick have bred mice that exhibit some of the same behaviors and brain abnormalities seen in humans with the disorder.

6 May 2024

Mindfulness training reduces dropout rates and relapses in opioid addiction treatment

Supplementing standard opioid addiction treatment with Mindfulness Oriented Recovery Enhancement (MORE) -; an intervention that incorporates mindfulness training, savoring skills, and cognitive reappraisal -; cuts program dropout rates by 59 percent and relapses by 42 percent, according to Rutgers-led research.

6 May 2024

CRISPR gene editing shows promise for treating individuals with a form of inherited blindness

Results from a groundbreaking clinical trial of CRISPR gene editing in 14 individuals with a form of inherited blindness show that the treatment is safe and led to measurable improvements in 11 of the participants treated.

6 May 2024

Plant-based medication may be an effective therapy to help people quit vaping

Eleven million U.S. adults use e-cigarettes to vape nicotine, and about half of them say that they want to stop, but many have trouble doing so because nicotine is an addictive drug.

6 May 2024

Durable lymph-node expansion improves vaccine responses against tumors

Each one of us has around 600 lymph nodes (LNs) – small, bean-shaped organs that house various types of blood cells and filter lymph fluid – scattered throughout our bodies.

6 May 2024

Key transport systems fuel rapid E. coli growth in UTIs

Through a quirk of anatomy, women are especially prone to urinary tract infections, with almost half dealing with one at some point in their lives.

3 May 2024

Researchers highlight critical need for more effective treatments for women with bacterial vaginosis

Bacterial Vaginosis (BV) affects about one-quarter of reproductive-age women and is linked to adverse health outcomes, such as increased HIV risk.

2 May 2024

Glycoengineered stem cells enhance brain recovery after cardiac arrest, study finds

Researchers at the University of Maryland School of Medicine have identified an innovation in stem cell therapy to regenerate neural cells in the brain after cardiac arrest in an animal model.

2 May 2024

Rapamycin shows promise in slowing Alzheimer's disease progression linked to seizures

Protein imbalances that increase brain cell excitability may explain why individuals with Alzheimer's disease (AD) who also experience seizures demonstrate more rapid cognitive decline than those who do not experience seizures.

2 May 2024

New brain connectivity maps offer insights into human consciousness

In a paper titled, "Multimodal MRI reveals brainstem connections that sustain wakefulness in human consciousness," published today in Science Translational Medicine, a group of researchers at Massachusetts General Hospital, a founding member of the Mass General Brigham healthcare system, and Boston Children's Hospital, created a connectivity map of a brain network that they propose is critical to human consciousness.

2 May 2024

Study uncovers molecular mechanism linking nonsense-mediated RNA decay to microcephaly

Nonsense-mediated RNA decay, or NMD, is an evolutionarily conserved molecular mechanism in which potentially defective messenger RNAs, or mRNAs (genetic material that instructs the body on how to make proteins), are degraded.

1 May 2024

Machine learning tool can speed the diagnosis of undiagnosed patients with rare immune disorders

Researchers say a machine learning tool can identify many patients with rare, undiagnosed diseases years earlier, potentially improving outcomes and reducing cost and morbidity. The findings, led by researchers at UCLA Health, are described in Science Translational Medicine.

1 May 2024

Genes affecting worm behavior found to be relevant to neurological disease in humans

As an undergraduate student in The University of Texas at Arlington's Honors College, Hannah Selvarathinam knew she wanted to conduct research. Near the end of her first year at UTA, the Keller native reached out to the lab of biology Assistant Professor Piya Ghose.

30 Apr 2024

Progression of subtle CT abnormalities in smokers predicts acute respiratory disease

Smokers who have small abnormalities on their CT scans that grow over time have a greater likelihood of experiencing acute respiratory disease events, according to a new study published today in Radiology, a journal of the Radiological Society of North America.

30 Apr 2024

Study reveals genetic divergence and drug resistance mechanisms in two critical superbugs

Infectious diseases caused by pathogenic strains of bacteria are a global cause of morbidity and mortality. Hospital-acquired infections caused by Klebsiella pneumonia and Pseudomonas aeruginosa were found vulnerable during the COVID-19 pandemic.

29 Apr 2024

Genetic associations of key genes in breast cancer pathogenesis

Breast cancer remains a significant global health concern, warranting further exploration into its genetic basis and potential therapeutic targets.

29 Apr 2024

Benefits and challenges of integrating nursing home residents into clinical trials

Clinical trials are constantly being designed and study participants enrolled to determine if medical treatments and therapies are safe and effective.

29 Apr 2024

Study shows link between air pollution, stress, and heart health risk

A study in more than 3,000 US counties, with 315 million residents, has suggested that air pollution is linked with stress and depression, putting under-65-year-olds at increased risk of dying from cardiovascular disease.

26 Apr 2024

Study suggests a common brain network exists between heart rate deceleration and depression

A new study by researchers at Brigham and Women's Hospital, a founding member of the Mass General Brigham healthcare system, suggests a common brain network exists between heart rate deceleration and depression.

26 Apr 2024

Research reveals mortality disparities among sexual minority women

Compared to heterosexual women, bisexual women died 37% sooner and lesbian women 20% sooner, according to results from one of the largest studies to examine sexual orientation-related inequities in mortality and the first to differentiate between lesbians and bisexual women.

25 Apr 2024

Medical School News and Research

Rutgers scientists create CRISPR-edited mice to study the neurobiology of Tourette disorder

Mindfulness training reduces dropout rates and relapses in opioid addiction treatment

CRISPR gene editing shows promise for treating individuals with a form of inherited blindness

Plant-based medication may be an effective therapy to help people quit vaping

Durable lymph-node expansion improves vaccine responses against tumors

Key transport systems fuel rapid E. coli growth in UTIs

Researchers highlight critical need for more effective treatments for women with bacterial vaginosis

Glycoengineered stem cells enhance brain recovery after cardiac arrest, study finds

Rapamycin shows promise in slowing Alzheimer's disease progression linked to seizures

New brain connectivity maps offer insights into human consciousness

Study uncovers molecular mechanism linking nonsense-mediated RNA decay to microcephaly

Machine learning tool can speed the diagnosis of undiagnosed patients with rare immune disorders

Genes affecting worm behavior found to be relevant to neurological disease in humans

Progression of subtle CT abnormalities in smokers predicts acute respiratory disease

Study reveals genetic divergence and drug resistance mechanisms in two critical superbugs

Genetic associations of key genes in breast cancer pathogenesis

Benefits and challenges of integrating nursing home residents into clinical trials

Study shows link between air pollution, stress, and heart health risk

Study suggests a common brain network exists between heart rate deceleration and depression

Research reveals mortality disparities among sexual minority women

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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